dapsone and Cerebral Infarction, Middle Cerebral Artery studies

dapsone and Cerebral Infarction, Middle Cerebral Artery

Research Excerpts

Excerpt	Relevance	Reference
"Male adult Wistar rats were subjected to middle cerebral artery occlusion (MCAO) for 90 min followed by 24 h of ischemic reperfusion (I/R)."	1.56	Dapsone prolong delayed excitotoxic neuronal cell death by interacting with proapoptotic/survival signaling proteins. ( Gakare, S; Kumar, R; Mahale, A; Prakash, A; Sarode, LP; Ugale, RR, 2020)
"Dapsone-treated animals showed a reduction of 93% (9."	1.32	Neuroprotective effect of dapsone in an occlusive model of focal ischemia in rats. ( Nader-Kawachi, J; Nava-Ruiz, C; Ríos, C; Rodriguez-Payán, AJ, 2004)

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	1 (50.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

1 (50.00)

29.6817

2010's

0 (0.00)

24.3611

2020's

1 (50.00)

2.80

Authors

Authors	Studies
Mahale, A	1
Kumar, R	1
Sarode, LP	1
Gakare, S	1
Prakash, A	1
Ugale, RR	1
Ríos, C	1
Nader-Kawachi, J	1
Rodriguez-Payán, AJ	1
Nava-Ruiz, C	1

Studies

Mahale, A

Kumar, R

Sarode, LP

Gakare, S

Prakash, A

Ugale, RR

Ríos, C

Nader-Kawachi, J

Rodriguez-Payán, AJ

Nava-Ruiz, C

Clinical Trials (1)

Trial Overview

Trial	Phase	Enrollment	Study Type	Start Date	Status
Neuroprotective Effect of Dapsone in Patients With Aneurysmal Subarachnoid Hemorrhage: Prospective, Randomized, Double-Blinded, Placebo-Controlled, Clinical Trial[NCT05131295]	Phase 3	49 participants (Actual)	Interventional	2007-09-05	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial

Phase

Enrollment

Study Type

Start Date

Status

Neuroprotective Effect of Dapsone in Patients With Aneurysmal Subarachnoid Hemorrhage: Prospective, Randomized, Double-Blinded, Placebo-Controlled, Clinical Trial[NCT05131295]

Phase 3

49 participants (Actual)

Interventional

2007-09-05

Completed

[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

2 other studies available for dapsone and Cerebral Infarction, Middle Cerebral Artery

Article	Year
Dapsone prolong delayed excitotoxic neuronal cell death by interacting with proapoptotic/survival signaling proteins. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2020, Volume: 29, Issue:8 Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Brain; Cells, Cultured; Dapsone; Disease Models,	2020
Neuroprotective effect of dapsone in an occlusive model of focal ischemia in rats. Brain research, 2004, Mar-05, Volume: 999, Issue:2 Topics: Animals; Brain Infarction; Brain Ischemia; Dapsone; Disease Models, Animal; Dose-Response Relationsh	2004

Article

Year

Dapsone prolong delayed excitotoxic neuronal cell death by interacting with proapoptotic/survival signaling proteins.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2020, Volume: 29, Issue:8

Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Brain; Cells, Cultured; Dapsone; Disease Models,

2020

Neuroprotective effect of dapsone in an occlusive model of focal ischemia in rats.

Brain research, 2004, Mar-05, Volume: 999, Issue:2

Topics: Animals; Brain Infarction; Brain Ischemia; Dapsone; Disease Models, Animal; Dose-Response Relationsh

2004