Page last updated: 2024-10-25

dapsone and Borderline Lepromatous

dapsone has been researched along with Borderline Lepromatous in 17 studies

Research Excerpts

ExcerptRelevanceReference
"The World Health Organization (WHO) recommends multidrug therapy (MDT) with rifampicin, dapsone, and clofazimine for treating leprosy, which is based on very low-quality evidence."5.41Seventy years of evidence on the efficacy and safety of drugs for treating leprosy: a network meta-analysis. ( Bao, F; Chen, J; Dong, Y; Fan, Y; Gao, L; Ji, Z; Kong, J; Li, B; Liu, A; Liu, M; Luo, S; Ma, W; Peng, L; Song, J; Wu, X; Yang, J, 2023)
"In this study, the authors compare plasma dapsone trough levels of multibacillary leprosy subjects stratified by body mass index (BMI) to evaluate if obesity plays a significant role on drug levels."3.80Dapsone and body mass index in subjects with multibacillary leprosy. ( Araujo, EC; Brasil, LM; Dias, RM; Ferreira, MV; Moura, FM; Vieira, JL, 2014)
"This study sought to verify the correlation between leprosy types and the adverse effects of treatment drugs."2.77Brazilian clinical trial of uniform multidrug therapy for leprosy patients: the correlation between clinical disease types and adverse effects. ( Almeida, PC; Bührer-Sékula, S; Cruz, R; Gonçalves, Hde S; Moraes, ME; Penna, GO; Pontes, MA, 2012)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (5.88)29.6817
2010's14 (82.35)24.3611
2020's2 (11.76)2.80

Authors

AuthorsStudies
Chew, R1
Woods, ML1
Yang, J1
Kong, J1
Li, B1
Ji, Z1
Liu, A1
Chen, J1
Liu, M1
Fan, Y1
Peng, L1
Song, J1
Wu, X1
Gao, L1
Ma, W1
Dong, Y1
Luo, S1
Bao, F1
Penna, GO2
Bührer-Sékula, S2
Kerr, LRS1
Stefani, MMA1
Rodrigues, LC1
de Araújo, MG1
Ramos, AMC1
de Andrade, ARC1
Costa, MB1
Rosa, PS1
Gonçalves, HS1
Cruz, R2
Barreto, ML1
Pontes, MAA1
Penna, MLF1
Pawar, M1
Zawar, V1
Kumavat, S1
Daga, S1
Craig, J1
MacRae, C1
Melvin, RG1
Boggild, AK1
Weberschock, T1
Göttig, S1
Moura, FM1
Dias, RM1
Araujo, EC1
Brasil, LM1
Ferreira, MV1
Vieira, JL1
El Morabite, K1
Tbatou, F1
Ait Ourhroui, M1
Senouci, K1
Hassam, B1
Guerrero, MI1
Colorado, CL1
Torres, JF1
León, CI1
Shen, J1
Yan, L1
Yu, M1
Li, J1
Yu, X1
Zhang, G1
Ozturk, Z1
Tatliparmak, A1
Becker, L1
Kowalewski, C1
Martin, JM1
Hall, JM1
Torske, KR1
Kahn, MA1
Moreland, AA1
Moschella, SL1
Maghanoy, A1
Mallari, I1
Balagon, M2
Saunderson, P1
Ravanes, JM1
Cellona, RV1
Abalos, RM1
Walsh, GP1
Walsh, DS1
Gonçalves, Hde S1
Pontes, MA1
Almeida, PC1
Moraes, ME1
Cunha, Mda G1
Virmond, M1
Schettini, AP1
Cruz, RC1
Ura, S1
Ghuidella, C1
Viana, Fdos R1
Avelleira, JC1
Campos, AA1
Filho, B1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Independent Study to Establish the Efficacy of the Six Doses Uniform MDT Regimen (U-MDT) for Leprosy Patients[NCT00669643]Phase 4859 participants (Actual)Interventional2007-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for dapsone and Borderline Lepromatous

ArticleYear
Seventy years of evidence on the efficacy and safety of drugs for treating leprosy: a network meta-analysis.
    The Journal of infection, 2023, Volume: 86, Issue:4

    Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Humans; Leprostatic Agents; Leprosy; Leprosy, Multi

2023
Leprosy treatment during pregnancy and breastfeeding: A case report and brief review of literature.
    Dermatologic therapy, 2017, Volume: 30, Issue:1

    Topics: Adult; Breast Feeding; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Leprostatic

2017

Trials

4 trials available for dapsone and Borderline Lepromatous

ArticleYear
Uniform multidrug therapy for leprosy patients in Brazil (U-MDT/CT-BR): Results of an open label, randomized and controlled clinical trial, among multibacillary patients.
    PLoS neglected tropical diseases, 2017, Volume: 11, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brazil; Child; Child, Preschool; Clofazimine; Dapsone; D

2017
Longitudinal ocular survey of 202 Filipino patients with multi-bacillary (MB) leprosy treated with 2 year WHO-multiple drug therapy.
    The Southeast Asian journal of tropical medicine and public health, 2011, Volume: 42, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Clofazimine; Dapsone; Drug Ther

2011
Brazilian clinical trial of uniform multidrug therapy for leprosy patients: the correlation between clinical disease types and adverse effects.
    Memorias do Instituto Oswaldo Cruz, 2012, Volume: 107 Suppl 1

    Topics: Adolescent; Adult; Aged; Child; Clofazimine; Dapsone; Drug Therapy, Combination; Humans; Leprostatic

2012
OFLOXACIN multicentre trial in MB leprosy FUAM-Manaus and ILSL-Bauru, Brazil.
    Leprosy review, 2012, Volume: 83, Issue:3

    Topics: Adolescent; Adult; Animals; Brazil; Clofazimine; Dapsone; Double-Blind Method; Drug Therapy, Combina

2012

Other Studies

11 other studies available for dapsone and Borderline Lepromatous

ArticleYear
Multibacillary Mid-Borderline Leprosy with Type 1 Lepra Reaction and Concurrent Latent Tuberculosis.
    The American journal of tropical medicine and hygiene, 2021, 10-25, Volume: 106, Issue:2

    Topics: Abattoirs; Anti-Inflammatory Agents; Antitubercular Agents; Clofazimine; Dapsone; Diagnosis, Differe

2021
Chronic, persistent angioedema and sinusitis-like presentation of multibacillary leprosy.
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2018, Volume: 16, Issue:4

    Topics: Adolescent; Angioedema; Biopsy; Chronic Disease; Clofazimine; Dapsone; Developing Countries; Diagnos

2018
Case Report: A Case of Type 1 Leprosy Reaction and Dapsone Hypersensitivity Syndrome Complicating the Clinical Course of Multibacillary Leprosy.
    The American journal of tropical medicine and hygiene, 2019, Volume: 100, Issue:5

    Topics: Dapsone; Drug Hypersensitivity; Drug Therapy, Combination; Female; Humans; Leprostatic Agents; Lepro

2019
A young man with livid facial nodules and a loss of eyebrows.
    The Lancet. Infectious diseases, 2013, Volume: 13, Issue:3

    Topics: Adult; Alopecia; Clofazimine; Dapsone; Eyebrows; Facial Dermatoses; Humans; Leprostatic Agents; Lepr

2013
Dapsone and body mass index in subjects with multibacillary leprosy.
    Therapeutic drug monitoring, 2014, Volume: 36, Issue:2

    Topics: Adult; Body Mass Index; Chromatography, High Pressure Liquid; Dapsone; Humans; Leprostatic Agents; L

2014
[Borderline lepromatous leprosy].
    Presse medicale (Paris, France : 1983), 2014, Volume: 43, Issue:6 Pt 1

    Topics: Adult; Biopsy; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Leprosy, Borderline;

2014
Is drug-resistant Mycobacterium leprae a real cause for concern?: First approach to molecular monitoring of multibacillary Colombian patients with and without previous leprosy treatment.
    Biomedica : revista del Instituto Nacional de Salud, 2014, Volume: 34 Suppl 1

    Topics: Adolescent; Adult; Bacterial Proteins; Biopsy; Child; Colombia; Dapsone; DNA, Bacterial; Drug Resist

2014
Six years' follow-up of multibacillary leprosy patients treated with uniform multi-drug therapy in China.
    International journal of dermatology, 2015, Volume: 54, Issue:3

    Topics: Adolescent; Adult; Aged; Child; China; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Foll

2015
Nonpruritic erythematous plaques.
    The Journal of family practice, 2009, Volume: 58, Issue:12

    Topics: Adult; Animals; Armadillos; Biopsy; Clofazimine; Dapsone; Diagnosis, Differential; Drug Therapy, Com

2009
Clinical-pathological conference: case 3.
    Head and neck pathology, 2010, Volume: 4, Issue:3

    Topics: Adult; Dapsone; Diagnosis, Differential; Drug Therapy, Combination; Humans; Immunologic Deficiency S

2010
Relapse study in smear positive multibacillary (MB) leprosy after 1 year WHO-multi-drug therapy (MDT) in Cebu, Philippines.
    Leprosy review, 2011, Volume: 82, Issue:1

    Topics: Adolescent; Adult; Aged; Child; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Lep

2011