Page last updated: 2024-10-25

dapsone and Aging

dapsone has been researched along with Aging in 7 studies

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"A 13% incidence of hepatitis was observed among 54 cases of multibacillary leprosy treated daily with the three-drug combination of dapsone, rifampin, and a thioamide (ethionamide or prothionamide)."7.66Hepatitis in leprosy patients treated by a daily combination of dapsone, rifampin, and a thioamide. ( Cartel, JL; Grosset, JH; Guelpa-Lauras, CC; Millan, J, 1983)
"A 13% incidence of hepatitis was observed among 54 cases of multibacillary leprosy treated daily with the three-drug combination of dapsone, rifampin, and a thioamide (ethionamide or prothionamide)."3.66Hepatitis in leprosy patients treated by a daily combination of dapsone, rifampin, and a thioamide. ( Cartel, JL; Grosset, JH; Guelpa-Lauras, CC; Millan, J, 1983)
" However, the suggested dosage regimen is based upon clinical experience with children with leprosy and dermatitis herpetiformis rather than pharmacokinetic and pharmacodynamic data obtained from the target patient population."2.68Pharmacokinetics of dapsone in human immunodeficiency virus-infected children. ( Bassetti, D; Casazza, R; Cruciani, M; Gatti, G; Loy, A; Miletich, F, 1995)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhang, T1
Tian, X1
Wang, Q1
Tong, Y1
Wang, H1
Li, Z1
Li, L1
Zhou, T1
Zhan, R1
Zhao, L1
Sun, Y1
Fan, D1
Lu, L1
Zhang, J1
Jin, Y1
Xiao, W1
Guo, X1
Chui, D1
Lee, YI1
Kang, H1
Ha, YW1
Chang, KY1
Cho, SC2
Song, SO1
Kim, H1
Jo, A1
Khang, R1
Choi, JY1
Lee, Y1
Park, SC2
Shin, JH1
Park, MC1
Keam, B1
Choi, JM1
Cho, Y1
Hyun, S1
Lee, J1
O'Connell, MB1
Frye, RF1
Matzke, GR1
St Peter, JV1
Willhite, LA1
Welch, MR1
Kowal, P1
LaValleur, J1
Cartel, JL1
Millan, J1
Guelpa-Lauras, CC1
Grosset, JH1
Gatti, G1
Loy, A1
Casazza, R1
Miletich, F1
Cruciani, M1
Bassetti, D1
Philip, PA1
Gayed, SL1
Rogers, HJ1
Crome, P1

Trials

2 trials available for dapsone and Aging

ArticleYear
Effect of conjugated equine estrogens on oxidative metabolism in middle-aged and elderly postmenopausal women.
    Journal of clinical pharmacology, 2006, Volume: 46, Issue:11

    Topics: Aged; Aging; Aryl Hydrocarbon Hydroxylases; Arylamine N-Acetyltransferase; Cytochrome P-450 CYP1A2;

2006
Pharmacokinetics of dapsone in human immunodeficiency virus-infected children.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:5

    Topics: Aging; Anti-Infective Agents; Child; Child, Preschool; Dapsone; Female; Half-Life; HIV Infections; H

1995

Other Studies

5 other studies available for dapsone and Aging

ArticleYear
Surgical stress induced depressive and anxiety like behavior are improved by dapsone via modulating NADPH oxidase level.
    Neuroscience letters, 2015, Jan-12, Volume: 585

    Topics: Aging; Animals; Antioxidants; Anxiety; Brain; Dapsone; Depression; Male; Mice, Inbred C57BL; NADPH O

2015
Diaminodiphenyl sulfone-induced parkin ameliorates age-dependent dopaminergic neuronal loss.
    Neurobiology of aging, 2016, Volume: 41

    Topics: Activating Transcription Factor 4; Aging; Animals; Anti-Inflammatory Agents; Brain; Cells, Cultured;

2016
DDS, 4,4'-diaminodiphenylsulfone, extends organismic lifespan.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Nov-09, Volume: 107, Issue:45

    Topics: Aging; Animals; Antioxidants; Caenorhabditis elegans; Cell Line; Dapsone; Longevity; Mitochondrial P

2010
Hepatitis in leprosy patients treated by a daily combination of dapsone, rifampin, and a thioamide.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1983, Volume: 51, Issue:4

    Topics: Adolescent; Adult; Aging; Amides; Chemical and Drug Induced Liver Injury; Dapsone; Drug Therapy, Com

1983
Influence of age, sex and body weight on the dapsone acetylation phenotype.
    British journal of clinical pharmacology, 1987, Volume: 23, Issue:6

    Topics: Acetylation; Adult; Aging; Body Weight; Dapsone; Female; Humans; Male; Phenotype; Sex Factors

1987