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dapsone and Acute Liver Injury, Drug-Induced

dapsone has been researched along with Acute Liver Injury, Drug-Induced in 47 studies

Research Excerpts

ExcerptRelevanceReference
"During treatment of multibacillary leprosy with the combination rifampin (RMP) 600 mg, ethionamide (ETH) 500 mg, and either dapsone (DDS) or clofazimine (CLO) 100 mg, hepatotoxicity was observed in 4."9.05Hepatotoxicity of the combination of rifampin-ethionamide in the treatment of multibacillary leprosy. ( Bourland, J; Davies, EM; Feracci, C; Grillone, S; Janssens, L; Pattyn, SR; Saylan, T, 1984)
"Dapsone hypersensitivity syndrome (DHS) is a potentially life-threatening adverse drug reaction consisting of fever, hepatitis, exfoliative dermatitis, lymphadenopathy and hemolytic anemia."7.75Dapsone hypersensitivity syndrome in non-leprosy patients: a retrospective study of its incidence in a tertiary referral center in Taiwan. ( Chu, CY; Sheen, YS; Tsai, TF; Wang, SH, 2009)
"A 34-year-old woman with HIV infection and no other opportunistic infections presented a classic sulfone syndrome, manifested by fever, rash, hemolytic anemia, and fulminant hepatitis due to dapsone hypersensitive reaction, with a fatal outcome."7.69Dapsone therapy causing sulfone syndrome and lethal hepatic failure in an HIV-infected patient. ( Baffoe-Bonnie, H; Chalasani, P; Jurado, RL, 1994)
"Side-effects of leprosy treatment with dapsone are said to be uncommon, with drug allergy occurring in only one of every several hundred patients treated with dapsone."7.68Dapsone syndrome in Vanuatu: a high incidence during multidrug treatment (MDT) of leprosy. ( Ala, J; Hall, JJ; Reeve, PA, 1992)
"A 13% incidence of hepatitis was observed among 54 cases of multibacillary leprosy treated daily with the three-drug combination of dapsone, rifampin, and a thioamide (ethionamide or prothionamide)."7.66Hepatitis in leprosy patients treated by a daily combination of dapsone, rifampin, and a thioamide. ( Cartel, JL; Grosset, JH; Guelpa-Lauras, CC; Millan, J, 1983)
"In patients with AIDS, oral therapy with trimethoprim-sulfamethoxazole and with trimethoprim-dapsone are equally effective for mild-to-moderate first episodes of P."6.67Oral therapy for Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. A controlled trial of trimethoprim-sulfamethoxazole versus trimethoprim-dapsone. ( Benowitz, N; Hopewell, PC; Lee, B; Leoung, G; Medina, I; Mills, J; Modin, G; Wofsy, CB, 1990)
"Dapsone therapy was initiated on day +28 at a dose of 100 mg/day for PCP prophylaxis secondary to the patient's history of a sulfonamide allergy."5.33The sulfone syndrome secondary to dapsone prophylaxis in a patient undergoing unrelated hematopoietic stem cell transplantation. ( Abidi, MH; Ibrahim, RB; Kozlowski, JR; Peres, E, 2006)
"During treatment of multibacillary leprosy with the combination rifampin (RMP) 600 mg, ethionamide (ETH) 500 mg, and either dapsone (DDS) or clofazimine (CLO) 100 mg, hepatotoxicity was observed in 4."5.05Hepatotoxicity of the combination of rifampin-ethionamide in the treatment of multibacillary leprosy. ( Bourland, J; Davies, EM; Feracci, C; Grillone, S; Janssens, L; Pattyn, SR; Saylan, T, 1984)
"Dapsone hypersensitivity syndrome (DHS) is a potentially life-threatening adverse drug reaction consisting of fever, hepatitis, exfoliative dermatitis, lymphadenopathy and hemolytic anemia."3.75Dapsone hypersensitivity syndrome in non-leprosy patients: a retrospective study of its incidence in a tertiary referral center in Taiwan. ( Chu, CY; Sheen, YS; Tsai, TF; Wang, SH, 2009)
"An elderly patient with borderline tuberculoid Hansen's disease (leprosy) developed the diaminodiphenylsulphone syndrome after approximately 8 weeks of multi-drug therapy comprising dapsone and rifampicin."3.69A fatal case of drug-induced multi-organ damage in a patient with Hansen's disease: dapsone syndrome or rifampicin toxicity? ( Lau, G, 1995)
"A male patient who was being treated with oral prednisone for erosive mucocutaneous pemphigus lesions developed fever, jaundice, a rash, and anemia within 2 wk of starting dapsone therapy."3.69Sulfone syndrome in a patient receiving steroids for pemphigus. ( Barnard, GF; Dagher, RK; Scharf, MJ, 1994)
"A 34-year-old woman with HIV infection and no other opportunistic infections presented a classic sulfone syndrome, manifested by fever, rash, hemolytic anemia, and fulminant hepatitis due to dapsone hypersensitive reaction, with a fatal outcome."3.69Dapsone therapy causing sulfone syndrome and lethal hepatic failure in an HIV-infected patient. ( Baffoe-Bonnie, H; Chalasani, P; Jurado, RL, 1994)
"Side-effects of leprosy treatment with dapsone are said to be uncommon, with drug allergy occurring in only one of every several hundred patients treated with dapsone."3.68Dapsone syndrome in Vanuatu: a high incidence during multidrug treatment (MDT) of leprosy. ( Ala, J; Hall, JJ; Reeve, PA, 1992)
"A patient being treated with dapsone developed a hypersensitivity reaction with typical features of the "sulfone syndrome," including fever, malalse, and hepatitis."3.67Liver involvement in the sulfone syndrome. ( Cattau, EL; Johnson, DA; Kuritsky, JN; Zimmerman, HJ, 1986)
"Exfoliative dermatitis associated with hepatitis has been reported in leprosy patients taking dapsone in daily dosage of 200 mg daily or more previously."3.66Sulphone induced exfoliative dermatitis and hepatitis. ( Garg, BR; Lal, S, 1980)
"A 13% incidence of hepatitis was observed among 54 cases of multibacillary leprosy treated daily with the three-drug combination of dapsone, rifampin, and a thioamide (ethionamide or prothionamide)."3.66Hepatitis in leprosy patients treated by a daily combination of dapsone, rifampin, and a thioamide. ( Cartel, JL; Grosset, JH; Guelpa-Lauras, CC; Millan, J, 1983)
"In patients with AIDS, oral therapy with trimethoprim-sulfamethoxazole and with trimethoprim-dapsone are equally effective for mild-to-moderate first episodes of P."2.67Oral therapy for Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. A controlled trial of trimethoprim-sulfamethoxazole versus trimethoprim-dapsone. ( Benowitz, N; Hopewell, PC; Lee, B; Leoung, G; Medina, I; Mills, J; Modin, G; Wofsy, CB, 1990)
"Drugs producing acute liver failure (ALF) are uncommon and vary geographically."1.48Drug-induced acute liver failure in children and adults: Results of a single-centre study of 128 patients. ( Devarbhavi, H; Ganga, D; Joseph, T; Patil, M; Reddy, VV; Singh, R, 2018)
"Dapsone is a sulfone-type drug used widely for different infectious, immune, and hypersensitivity disorders as an antibacterial treatment alone or in combination for leprosy and sometimes for infected skin lesions."1.40Fulminant hepatitis linked to dapsone hypersensitivity syndrome requiring urgent living donor liver transplantation: a case report. ( Choi, YR; Garcia, A; Hong, G; Kang, EK; Kang, HJ; Kim, JG; Lee, JM; Lee, KB; Lee, KW; Park, JD; Suh, KS; Suh, SW; Yi, NJ; You, T, 2014)
" An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification of potential toxic effects early in the drug development process and aid in avoiding such problems."1.36Developing structure-activity relationships for the prediction of hepatotoxicity. ( Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ, 2010)
"Dapsone therapy was initiated on day +28 at a dose of 100 mg/day for PCP prophylaxis secondary to the patient's history of a sulfonamide allergy."1.33The sulfone syndrome secondary to dapsone prophylaxis in a patient undergoing unrelated hematopoietic stem cell transplantation. ( Abidi, MH; Ibrahim, RB; Kozlowski, JR; Peres, E, 2006)
" Once the patient's liver function normalized, prednisone dosage was reduced by 5 mg weekly."1.29Dapsone hypersensitivity syndrome. ( Prussick, R; Shear, NH, 1996)
" Dosage data indicated that fatalities had taken higher doses and continued prophylaxis after onset of symptoms."1.28Serious adverse drug reactions to pyrimethamine-sulphadoxine, pyrimethamine-dapsone and to amodiaquine in Britain. ( Phillips-Howard, PA; West, LJ, 1990)

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-199010 (21.28)18.7374
1990's15 (31.91)18.2507
2000's5 (10.64)29.6817
2010's15 (31.91)24.3611
2020's2 (4.26)2.80

Authors

AuthorsStudies
Fourches, D1
Barnes, JC1
Day, NC1
Bradley, P1
Reed, JZ1
Tropsha, A1
Greene, N1
Fisk, L1
Naven, RT1
Note, RR1
Patel, ML1
Pelletier, DJ1
Morgan, RE2
Trauner, M1
van Staden, CJ2
Lee, PH1
Ramachandran, B1
Eschenberg, M1
Afshari, CA2
Qualls, CW1
Lightfoot-Dunn, R1
Hamadeh, HK2
Ekins, S1
Williams, AJ1
Xu, JJ1
Dawson, S1
Stahl, S2
Paul, N1
Barber, J1
Kenna, JG2
Liu, Z1
Shi, Q1
Ding, D1
Kelly, R1
Fang, H1
Tong, W2
Sakatis, MZ1
Reese, MJ1
Harrell, AW1
Taylor, MA1
Baines, IA1
Chen, L1
Bloomer, JC1
Yang, EY1
Ellens, HM1
Ambroso, JL1
Lovatt, CA1
Ayrton, AD1
Clarke, SE1
Warner, DJ1
Chen, H1
Cantin, LD1
Walker, CL1
Noeske, T1
Chen, Y1
Kalyanaraman, N1
Kalanzi, J1
Dunn, RT1
Chen, M1
Suzuki, A1
Thakkar, S1
Yu, K1
Hu, C1
Ezhilarasan, D1
Devarbhavi, H2
Patil, M2
Menon, M1
Reddy, VV1
Singh, R1
Joseph, T1
Ganga, D1
Wonnaparhown, A1
Chung, C1
Shadix, S1
Patel, R1
Pandat, S1
Chinchilla, D1
Lindgren, B1
Falk, J1
Ohata, C1
Nakama, T1
Garcia, A1
Yi, NJ1
Lee, KB1
Lee, JM1
Choi, YR1
Suh, SW1
You, T1
Lee, KW1
Park, JD1
Kang, HJ1
Kim, JG1
Kang, EK1
Hong, G1
Suh, KS1
Schulkes, KJ1
Tervaert, JW1
Rijken, F1
Haas, LE1
Ranawaka, RR1
Mendis, S1
Weerakoon, HS1
Sheen, YS1
Chu, CY1
Wang, SH1
Tsai, TF1
JELLIFFE, DB1
Abidi, MH1
Kozlowski, JR1
Ibrahim, RB1
Peres, E1
Tang, H1
Min, G1
Ge, B1
Li, Y1
Liu, X1
Jiang, S1
Revuz, J1
Hornac, P1
Pattyn, SR1
Janssens, L1
Bourland, J1
Saylan, T1
Davies, EM1
Grillone, S1
Feracci, C1
Lal, S1
Garg, BR1
Tomecki, KJ1
Catalano, CJ1
Cartel, JL1
Millan, J1
Guelpa-Lauras, CC1
Grosset, JH1
Kromann, NP1
Vilhelmsen, R1
Stahl, D1
Dhamija, R1
Kumar, D1
Khurana, G1
Lau, G1
Risse, L1
Bernard, P1
Brosset, A1
Enginger, V1
Bedane, C1
Bonnetblanc, JM1
Puri, AS1
Gupta, R1
Ghoshal, UC1
Khan, E1
Aggarwal, R1
Naik, SR1
Barnard, GF1
Scharf, MJ1
Dagher, RK1
Chalasani, P1
Baffoe-Bonnie, H1
Jurado, RL1
Noble, A1
MacDonald, A1
Prussick, R1
Shear, NH1
Shuster, J1
Keiner, F1
Reeve, PA1
Ala, J1
Hall, JJ1
Lons, T1
Richardet, JP1
Machayekhi, JP1
Dalbergue, B1
Trinchet, JC1
Phillips-Howard, PA1
West, LJ1
Jayalakshmi, P1
Ting, HC1
Medina, I1
Mills, J1
Leoung, G1
Hopewell, PC1
Lee, B1
Modin, G1
Benowitz, N1
Wofsy, CB1
Lawrence, WA1
Olsen, HW1
Nickles, DJ1
Johnson, DA1
Cattau, EL1
Kuritsky, JN1
Zimmerman, HJ1

Reviews

4 reviews available for dapsone and Acute Liver Injury, Drug-Induced

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr

2016
Dapsone-induced hepatic complications: it's time to think beyond methemoglobinemia.
    Drug and chemical toxicology, 2021, Volume: 44, Issue:3

    Topics: Animals; Anti-Infective Agents; Chemical and Drug Induced Liver Injury; Dapsone; Dose-Response Relat

2021
[Side effects of treatment with sulfones].
    LARC medical, 1981, Volume: 1, Issue:3

    Topics: Adult; Agranulocytosis; Chemical and Drug Induced Liver Injury; Child; Dapsone; Drug Eruptions; Drug

1981
[Disulone hypersensitivity syndrome].
    Annales de dermatologie et de venereologie, 1994, Volume: 121, Issue:3

    Topics: Chemical and Drug Induced Liver Injury; Dapsone; Drug Hypersensitivity; Female; Fever; Humans; Middl

1994

Trials

3 trials available for dapsone and Acute Liver Injury, Drug-Induced

ArticleYear
Hepatotoxicity of the combination of rifampin-ethionamide in the treatment of multibacillary leprosy.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1984, Volume: 52, Issue:1

    Topics: Adolescent; Adult; Chemical and Drug Induced Liver Injury; Child; Clinical Trials as Topic; Clofazim

1984
Does isoniazid increase the hepatotoxicity of the combination prothionamide-dapsone? Isoprodian Study Group.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1992, Volume: 60, Issue:4

    Topics: Adolescent; Adult; Chemical and Drug Induced Liver Injury; Dapsone; Double-Blind Method; Drug Combin

1992
Oral therapy for Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. A controlled trial of trimethoprim-sulfamethoxazole versus trimethoprim-dapsone.
    The New England journal of medicine, 1990, Sep-20, Volume: 323, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Chemical and Drug Induced Liver Inj

1990

Other Studies

40 other studies available for dapsone and Acute Liver Injury, Drug-Induced

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship;

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters

2012
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily

2013
Association of human leukocyte antigen-B*13:01 with dapsone-induced liver injury.
    British journal of clinical pharmacology, 2022, Volume: 88, Issue:3

    Topics: Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Dapsone; HL

2022
Drug-induced acute liver failure in children and adults: Results of a single-centre study of 128 patients.
    Liver international : official journal of the International Association for the Study of the Liver, 2018, Volume: 38, Issue:7

    Topics: Adolescent; Adult; Anticonvulsants; Antitubercular Agents; Chemical and Drug Induced Liver Injury; C

2018
Liver injury, rash, and encephalopathy in a 23-year-old Asian man prescribed dapsone.
    The journal of allergy and clinical immunology. In practice, 2019, Volume: 7, Issue:3

    Topics: Adult; Anti-Infective Agents; Antiviral Agents; Brain Diseases; Chemical and Drug Induced Liver Inju

2019
Granuloma Faciale Treated Successfully with Colchicine.
    Acta dermato-venereologica, 2019, Jul-01, Volume: 99, Issue:9

    Topics: Chemical and Drug Induced Liver Injury; Colchicine; Dapsone; Dermatologic Agents; Drug Substitution;

2019
Fulminant hepatitis linked to dapsone hypersensitivity syndrome requiring urgent living donor liver transplantation: a case report.
    Pediatric transplantation, 2014, Volume: 18, Issue:7

    Topics: Adult; Chemical and Drug Induced Liver Injury; Child; Dapsone; Drug Hypersensitivity; Female; Humans

2014
Dapsone hypersensitivity syndrome not related to G6PD deficiency.
    BMJ case reports, 2015, Dec-18, Volume: 2015

    Topics: Anti-Infective Agents; Chemical and Drug Induced Liver Injury; Dapsone; Diagnosis, Differential; Dru

2015
Dapsone-induced haemolytic anaemia, hepatitis and agranulocytosis in a leprosy patient with normal glucose-6-phosphate-dehydrogenase activity.
    Leprosy review, 2008, Volume: 79, Issue:4

    Topics: Adult; Agranulocytosis; Anemia, Hemolytic; Chemical and Drug Induced Liver Injury; Dapsone; Glucosep

2008
Dapsone hypersensitivity syndrome in non-leprosy patients: a retrospective study of its incidence in a tertiary referral center in Taiwan.
    The Journal of dermatological treatment, 2009, Volume: 20, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Hemolytic; Chemical and Drug Induced Liver Injur

2009
French dapsone survey.
    Prescrire international, 2002, Volume: 11, Issue:62

    Topics: Chemical and Drug Induced Liver Injury; Dapsone; Drug Hypersensitivity; France; Health Care Surveys;

2002
Toxic hepatitis caused by diaminodiphenylsulphone.
    Lancet (London, England), 1951, Jun-23, Volume: 1, Issue:6669

    Topics: Chemical and Drug Induced Liver Injury; Dapsone; Hepatitis; Sulfones; Viral Vaccines

1951
The sulfone syndrome secondary to dapsone prophylaxis in a patient undergoing unrelated hematopoietic stem cell transplantation.
    Hematological oncology, 2006, Volume: 24, Issue:3

    Topics: Anemia, Hemolytic; Chemical and Drug Induced Liver Injury; Dapsone; Dermatitis, Exfoliative; Drug Hy

2006
Evaluation of protective effects of Chi-Zhi-Huang decoction on Phase I drug metabolism of liver injured rats by cocktail probe drugs.
    Journal of ethnopharmacology, 2008, May-22, Volume: 117, Issue:3

    Topics: Alanine Transaminase; Animals; Area Under Curve; Aspartate Aminotransferases; Bilirubin; Caffeine; C

2008
Sulphone induced exfoliative dermatitis and hepatitis.
    Leprosy in India, 1980, Volume: 52, Issue:2

    Topics: Adrenal Cortex Hormones; Adult; Chemical and Drug Induced Liver Injury; Dapsone; Dermatitis, Exfolia

1980
Dapsone hypersensitivity. The sulfone syndrome revisited.
    Archives of dermatology, 1981, Volume: 117, Issue:1

    Topics: Acne Vulgaris; Adolescent; Anemia, Hemolytic; Chemical and Drug Induced Liver Injury; Dapsone; Drug

1981
Hepatitis in leprosy patients treated by a daily combination of dapsone, rifampin, and a thioamide.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1983, Volume: 51, Issue:4

    Topics: Adolescent; Adult; Aging; Amides; Chemical and Drug Induced Liver Injury; Dapsone; Drug Therapy, Com

1983
The dapsone syndrome.
    Archives of dermatology, 1982, Volume: 118, Issue:7

    Topics: Adult; Chemical and Drug Induced Liver Injury; Dapsone; Drug Hypersensitivity; Female; Humans; Syndr

1982
Dapsone syndrome.
    Tropical doctor, 1995, Volume: 25, Issue:4

    Topics: Adult; Chemical and Drug Induced Liver Injury; Dapsone; Diagnosis, Differential; Drug Hypersensitivi

1995
A fatal case of drug-induced multi-organ damage in a patient with Hansen's disease: dapsone syndrome or rifampicin toxicity?
    Forensic science international, 1995, May-22, Volume: 73, Issue:2

    Topics: Acute Kidney Injury; Aged; Chemical and Drug Induced Liver Injury; Dapsone; Diagnosis, Differential;

1995
Hepatic injury in sulfone syndrome: hepatitis or cholestasis?
    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 1995, Volume: 14, Issue:1

    Topics: Adult; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Dapsone; Drug Hypersensiti

1995
Sulfone syndrome in a patient receiving steroids for pemphigus.
    The American journal of gastroenterology, 1994, Volume: 89, Issue:11

    Topics: Aged; Chemical and Drug Induced Liver Injury; Dapsone; Drug Hypersensitivity; Drug Therapy, Combinat

1994
Dapsone therapy causing sulfone syndrome and lethal hepatic failure in an HIV-infected patient.
    Southern medical journal, 1994, Volume: 87, Issue:11

    Topics: Adult; AIDS-Related Opportunistic Infections; Chemical and Drug Induced Liver Injury; Dapsone; Drug

1994
Drug-induced hepatotoxicity.
    The New England journal of medicine, 1996, Mar-28, Volume: 334, Issue:13

    Topics: Antimalarials; Chemical and Drug Induced Liver Injury; Dapsone; Drug Combinations; Drug Eruptions; H

1996
Dapsone hypersensitivity syndrome.
    Journal of the American Academy of Dermatology, 1996, Volume: 35, Issue:2 Pt 2

    Topics: Administration, Oral; Adult; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Chole

1996
Dapsone and liver failure.
    Nursing, 1998, Volume: 28, Issue:1

    Topics: Adult; Chemical and Drug Induced Liver Injury; Dapsone; Drug Monitoring; Humans; Liver Failure; Lupu

1998
[Toxic liver lesions caused by alcohol and chemicals].
    Die Medizinische Welt, 1978, Dec-22, Volume: 29, Issue:51-52

    Topics: Alcoholism; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Contraceptives, Oral, Hor

1978
Dapsone syndrome in Vanuatu: a high incidence during multidrug treatment (MDT) of leprosy.
    The Journal of tropical medicine and hygiene, 1992, Volume: 95, Issue:4

    Topics: Adolescent; Adult; Chemical and Drug Induced Liver Injury; Clofazimine; Dapsone; Drug Eruptions; Dru

1992
[Granulomatous hepatitis caused by dapsone].
    Gastroenterologie clinique et biologique, 1992, Volume: 16, Issue:3

    Topics: Adrenal Cortex Hormones; Aged; Chemical and Drug Induced Liver Injury; Dapsone; Drug Therapy, Combin

1992
Serious adverse drug reactions to pyrimethamine-sulphadoxine, pyrimethamine-dapsone and to amodiaquine in Britain.
    Journal of the Royal Society of Medicine, 1990, Volume: 83, Issue:2

    Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Chemical and Drug Induced Liver Injury; Child; Child,

1990
Dapsone-induced liver necrosis.
    Histopathology, 1990, Volume: 17, Issue:1

    Topics: Adult; Chemical and Drug Induced Liver Injury; Dapsone; Dermatitis, Seborrheic; Humans; Kidney; Male

1990
Dapsone hepatitis.
    Archives of internal medicine, 1987, Volume: 147, Issue:1

    Topics: Adult; Chemical and Drug Induced Liver Injury; Dapsone; Dermatitis Herpetiformis; Female; Humans

1987
Liver involvement in the sulfone syndrome.
    Archives of internal medicine, 1986, Volume: 146, Issue:5

    Topics: Chemical and Drug Induced Liver Injury; Dapsone; Drug Hypersensitivity; Female; Fever; Humans; Liver

1986