Page last updated: 2024-10-25

dapsone and AIDS-Related Opportunistic Infections

dapsone has been researched along with AIDS-Related Opportunistic Infections in 99 studies

AIDS-Related Opportunistic Infections: Opportunistic infections found in patients who test positive for human immunodeficiency virus (HIV). The most common include PNEUMOCYSTIS PNEUMONIA, Kaposi's sarcoma, cryptosporidiosis, herpes simplex, toxoplasmosis, cryptococcosis, and infections with Mycobacterium avium complex, Microsporidium, and Cytomegalovirus.

Research Excerpts

ExcerptRelevanceReference
"To evaluate combined prophylaxis for Pneumocystis carinii pneumonia (PCP) and toxoplasmic encephalitis, 533 patients with symptomatic human immunodeficiency virus infection and/or CD4 lymphocyte counts of < 200/microL were randomized to receive dapsone/pyrimethamine (200/75 mg once weekly) or aerosolized pentamidine (300 mg every 4 weeks)."9.08Once-weekly administration of dapsone/pyrimethamine vs. aerosolized pentamidine as combined prophylaxis for Pneumocystis carinii pneumonia and toxoplasmic encephalitis in human immunodeficiency virus-infected patients. ( Heald, A; Hirschel, B; Iten, A; Lazzarin, A; Oertle, D; Opravil, M; Pechère, M; Praz, G; Rüttimann, S; von Overbeck, J, 1995)
"A 34-year-old woman with HIV infection and no other opportunistic infections presented a classic sulfone syndrome, manifested by fever, rash, hemolytic anemia, and fulminant hepatitis due to dapsone hypersensitive reaction, with a fatal outcome."7.69Dapsone therapy causing sulfone syndrome and lethal hepatic failure in an HIV-infected patient. ( Baffoe-Bonnie, H; Chalasani, P; Jurado, RL, 1994)
"Dapsone was more effective in the primary prophylaxis of toxoplasmic encephalitis, with six toxoplasmic encephalitis events occurring among those receiving aerosolized pentamidine, compared to none among those taking dapsone (p = 0."6.67Randomized trial of dapsone and aerosolized pentamidine for the prophylaxis of Pneumocystis carinii pneumonia and toxoplasmic encephalitis. ( Barr, M; Carlo, C; Chanin, E; Gregory, G; Kiely, S; Martin, M; Thorn, M; Thornton, J; Torres, RA, 1993)
"To the best of our knowledge, acute generalised exanthematous pustulosis has not been reported as a reaction to dapsone in the setting of HIV."5.39Acute generalised exanthematous pustulosis induced by Pneumocystis jirovecii pneumonia prophylaxis with dapsone. ( Laws, P; Marsland, A; McQuillan, O; Vas, A, 2013)
"We report two cases of symptomatic hyperbilirubinemia attributed to atazanavir in conjunction with the Pneumocystis jirovecii pneumonia prophylaxis agent dapsone."5.38Symptomatic hyperbilirubinemia secondary to dapsone-induced hemolysis and atazanavir therapy. ( Blanton, LS; East, J, 2012)
"To evaluate combined prophylaxis for Pneumocystis carinii pneumonia (PCP) and toxoplasmic encephalitis, 533 patients with symptomatic human immunodeficiency virus infection and/or CD4 lymphocyte counts of < 200/microL were randomized to receive dapsone/pyrimethamine (200/75 mg once weekly) or aerosolized pentamidine (300 mg every 4 weeks)."5.08Once-weekly administration of dapsone/pyrimethamine vs. aerosolized pentamidine as combined prophylaxis for Pneumocystis carinii pneumonia and toxoplasmic encephalitis in human immunodeficiency virus-infected patients. ( Heald, A; Hirschel, B; Iten, A; Lazzarin, A; Oertle, D; Opravil, M; Pechère, M; Praz, G; Rüttimann, S; von Overbeck, J, 1995)
" For dapsone, among 100 patients given 100 mg daily instead of twice a week for 1 year (primary prophylaxis), seven fewer patients would develop P carinii pneumonia, but 17 more would have significant toxic reactions."4.79A meta-analysis of the relative efficacy and toxicity of Pneumocystis carinii prophylactic regimens. ( Cappelleri, JC; Ioannidis, JP; Lau, J; Sacks, HS; Skolnik, PR, 1996)
"In a meta-analysis, we examined the efficacy of aerosolized pentamidine, trimethoprim-sulfamethoxazole, and dapsone or dapsone/pyrimethamine for the prevention of Pneumocystis carinii pneumonia and toxoplasma encephalitis in patients with HIV infection."4.79Meta-analysis of prophylactic treatments against Pneumocystis carinii pneumonia and toxoplasma encephalitis in HIV-infected patients. ( Bucher, HC; Griffith, L; Guyatt, GH; Opravil, M, 1997)
"A 34-year-old woman with HIV infection and no other opportunistic infections presented a classic sulfone syndrome, manifested by fever, rash, hemolytic anemia, and fulminant hepatitis due to dapsone hypersensitive reaction, with a fatal outcome."3.69Dapsone therapy causing sulfone syndrome and lethal hepatic failure in an HIV-infected patient. ( Baffoe-Bonnie, H; Chalasani, P; Jurado, RL, 1994)
" Dapsone pharmacokinetic parameters were not associated with toxicity, but higher dapsone AUC was associated with decreased risk of PCP."2.70Population pharmacokinetics of dapsone in children with human immunodeficiency virus infection. ( Bonagura, VR; Capparelli, E; Cooper, E; Jacobus, D; Lindsey, J; McIntosh, K; Mirochnick, M; Mofenson, L; Nachman, S; Spector, SA; Sullivan, JL; Xu, J; Yogev, R, 2001)
"Dapsone is an alternative drug for Pneumocystis carinii pneumonia (PCP) prophylaxis in individuals intolerant to trimethoprim-sulfamethoxazole (T/S)."2.69Toxicity and efficacy of daily vs. weekly dapsone for prevention of Pneumocystis carinii pneumonia in children infected with human immunodeficiency virus. ACTG 179 Study Team. AIDS Clinical Trials Group. ( Bonagura, V; Cooper, E; Jacobus, D; Kovacs, A; Lindsey, J; McIntosh, K; McNamara, J; Mirochnick, M; Mofenson, L; Nachman, S; Sacks, H; Sleasman, J; Spector, SA; Sullivan, JL; Xu, J; Yogev, R, 1999)
" Serial blood samples were obtained over 24 hours after dosing and analyzed for trimetrexate, dapsone, and monoacetyldapsone, and pharmacokinetic parameters were determined."2.69Pharmacokinetics of trimetrexate and dapsone in AIDS patients with Pneumocystis carinii pneumonia. ( Chatterjee, DJ; Dubé, MP; Koda, RT; Li, WY; Sattler, FR; Stansell, JD, 1999)
"Rifampin was found to increase the values of clearance/bioavailability (CL/F) and volume of distribution/ bioavailability (V/F) by approximately 70%."2.68Population pharmacokinetics of dapsone administered biweekly to human immunodeficiency virus-infected patients. ( Bassetti, D; Casazza, R; Cruciani, M; Gatti, G; Hossein, J; Karlsson, M; Merighi, M; Travaini, S, 1996)
" There was no significant difference in the occurrence of serious adverse reactions (six in the dapsone and eight in the pentamidine arm)."2.67Oral dapsone versus nebulized pentamidine for Pneumocystis carinii pneumonia prophylaxis: an open randomized prospective trial to assess efficacy and haematological toxicity. ( Hoy, JF; Kent, SJ; Lucas, CR; Pettinger, MB; Slavin, MA; Stewart, K, 1992)
"Dapsone was discontinued in nine (39%) patients because of adverse reactions."2.67Utility of dapsone for prophylaxis of Pneumocystis carinii pneumonia in trimethoprim-sulfamethoxazole-intolerant, HIV-infected individuals. ( Horowitz, HW; Jorde, UP; Wormser, GP, 1993)
"Standard treatments of HIV-associated Pneumocystis carinii pneumonia (PCP) consist of high dose intravenous or oral cotrimoxazole or intravenous pentamidine."2.67[Successful treatment of HIV-associated pneumocystis carinii pneumonia with dapsone plus trimethoprim]. ( Laifer, G; Rüttimann, S, 1992)
" The pharmacokinetics of dapsone and pyrimethamine were examined by using a population pharmacokinetic model."2.67Pharmacokinetics and safety of weekly dapsone and dapsone plus pyrimethamine for prevention of pneumocystis pneumonia. ( Amantea, MA; Byrne, A; Davey, RT; Falloon, J; Graziani, A; Lavelle, J; Morgan, A; Ogata-Arakaki, D; Ownby, K; Polis, M, 1994)
"Dapsone was more effective in the primary prophylaxis of toxoplasmic encephalitis, with six toxoplasmic encephalitis events occurring among those receiving aerosolized pentamidine, compared to none among those taking dapsone (p = 0."2.67Randomized trial of dapsone and aerosolized pentamidine for the prophylaxis of Pneumocystis carinii pneumonia and toxoplasmic encephalitis. ( Barr, M; Carlo, C; Chanin, E; Gregory, G; Kiely, S; Martin, M; Thorn, M; Thornton, J; Torres, RA, 1993)
"We report a case of P carinii infection presenting as bilateral aural polyps, otitis media and mastoiditis in human immunodeficiency (HIV)-positive patient with no history of prior or concomitant P carinii infection."2.41Pneumocystis carinii infection in bilateral aural polyps in a human immunodeficiency virus-positive patient. ( Elmahallawy, M; Horsfield, C; Praveen, CV; Terry, RM, 2002)
"Although the incidence of Pneumocystis carinii pneumonia (PCP) among adults infected with human immunodeficiency virus (HIV) has declined, no decline in PCP incidence has been observed among HIV-infected children, and PCP remains the most common serious opportunistic infection among both adults and children in the United States."2.39Preventing Pneumocystis carinii pneumonia in persons infected with human immunodeficiency virus. ( Feinberg, J; Hughes, WT; Navin, TR; Simonds, RJ, 1995)
"To the best of our knowledge, acute generalised exanthematous pustulosis has not been reported as a reaction to dapsone in the setting of HIV."1.39Acute generalised exanthematous pustulosis induced by Pneumocystis jirovecii pneumonia prophylaxis with dapsone. ( Laws, P; Marsland, A; McQuillan, O; Vas, A, 2013)
"We report two cases of symptomatic hyperbilirubinemia attributed to atazanavir in conjunction with the Pneumocystis jirovecii pneumonia prophylaxis agent dapsone."1.38Symptomatic hyperbilirubinemia secondary to dapsone-induced hemolysis and atazanavir therapy. ( Blanton, LS; East, J, 2012)
"Dapsone has several adverse effects in its profile that make it a potentially dangerous second-line agent."1.33Adverse reactions associated with dapsone therapy in HIV-positive patients: a case presentation and review. ( Miller, JA; Reust, R; Stephens, JR; Stroup, JS, 2006)
"PCR sensitivity and specificity were 100 and 86."1.32Detection of Pneumocystis carinii and characterization of mutations associated with sulfa resistance in bronchoalveolar lavage samples from human immunodeficiency virus-infected subjects. ( Carrera, P; Lazzarin, A; Scarpellini, P; Zingale, A, 2003)
"We describe the course of 36 AIDS patients with cerebral toxoplasmosis and present a review of clinical signs, diagnosis, therapy, and survival times."1.31[HIV-associated cerebral toxoplasmosis -- review and retrospective analysis of 36 patients]. ( Evers, S; Fischer, A; Freund, M; Grüneberg, U; Happe, S; Heese, Ch; Husstedt, IW; Kloska, S; Reichelt, D, 2002)
"Failures of prophylaxis against Pneumocystis carinii pneumonia (PCP) in AIDS patients do occur, but no evidence for drug resistance has yet been presented."1.30Pneumocystis carinii mutations associated with sulfa and sulfone prophylaxis failures in AIDS patients. ( Bartlett, MS; Cannon, M; Hossler, PA; Kazanjian, P; Lane, BR; Locke, AB; Meshnick, SR; Smith, JW, 1998)
" Dosing or frequency of TMP-SMX did not seem to influence risk of chemoprophylaxis failure."1.30Pneumocystis carinii pneumonia incidence and chemoprophylaxis failure in ambulatory HIV-infected patients. HIV Outpatient Study (HOPS) Investigators. ( Holmberg, SD; Moorman, AC; Palella, FJ; Von Bargen, JC, 1998)
"Dapsone is a cheap and effective prophylactic agent against P carinii in patients who cannot tolerate trimethoprim-sulfamethoxazole."1.30Bilateral upper-lobe cavitary Pneumocystis carinii pneumonia in a patient on dapsone prophylaxis. ( Anandarao, N; Dama, S; Jawahar, DA; Miarrostami, R; Sadagdhar, H, 1999)
" Overall results from these studies indicate patients who are eligible for PCP prophylaxis should be advised to take double-strength trimethoprim/sulfamethoxazole (TMP/SMX) on a daily basis, a dosage found more effective than thrice-weekly."1.30Optimizing PCP therapy. ( Cadman, J; Torres, G, 1997)
"Extrapulmonary pneumocystosis is a feature of severe immunosuppression which earlier reports have suggested is limited to patients receiving either no prophylaxis or aerosolised pentamidine."1.29Systemic Pneumocystis carinii pneumonia prophylaxis with dapsone and pyrimethamine fails to protect against extrapulmonary pneumocystosis. ( Carlin, EM; Coker, RJ; Goldin, RD; Harris, JR, 1993)
"Pneumocystis carinii pneumonia has been the most common life-threatening opportunistic infection in patients with acquired immunodeficiency syndrome."1.29Dilemmas in the prophylaxis of Pneumocystis carinii pneumonia. ( Glatt, AE, 1994)
"Bacteremia was caused by Staphylococcus aureus (23%), Pseudomonas aeruginosa (18%), Escherichia coli (16%), Streptococcus pneumoniae (14%) and others (31%)."1.29Community-acquired bacteremia in HIV-positive patients: protective benefit of co-trimoxazole. ( Edge, MD; Rimland, D, 1996)
"One patient had a recurrence of PCP at 4 mo, after a negative 1-mo BAL."1.29Persistence of Pneumocystis carinii in patients with AIDS receiving chemoprophylaxis. ( Antonson, S; Epstein, LJ; Meyer, RD; Mohsenifar, Z; Strigle, SM, 1994)
"carinii prophylaxis before the onset of AIDS: Mycobacterium avium complex disease, which developed in 33."1.29Clinical manifestations of AIDS in the era of pneumocystis prophylaxis. Multicenter AIDS Cohort Study. ( Anderson, R; Bacellar, H; Detels, R; Hoover, DR; Kaslow, RA; Phair, J; Saah, AJ, 1993)
"Occurrence or recurrence of PCP."1.29Predictors for failure of Pneumocystis carinii pneumonia prophylaxis. Multicenter AIDS Cohort Study. ( Hoover, DR; Kingsley, LA; Peng, Y; Phair, JP; Saah, AJ; Schrager, LK; Visscher, B, 1995)
" Three of the 20 patients had an adverse reaction to dapsone."1.29Efficacy and safety of dapsone prophylaxis against Pneumocystis carinii pneumonia in human immunodeficiency virus-infected children. ( Noel, GJ; Stavola, JJ, 1993)
" Ro 11-8958, TMP, and diaveridine used at a dosage of 20 mg/kg/day with SMX were only slightly more effective than SMX used alone."1.29Synergistic combinations of Ro 11-8958 and other dihydrofolate reductase inhibitors with sulfamethoxazole and dapsone for therapy of experimental pneumocystosis. ( Foy, J; Steele, P; Walzer, PD; White, M, 1993)

Research

Studies (99)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's75 (75.76)18.2507
2000's20 (20.20)29.6817
2010's4 (4.04)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vas, A1
Laws, P1
Marsland, A1
McQuillan, O1
Ponce, CA1
Chabé, M1
George, C1
Cárdenas, A1
Durán, L1
Guerrero, J1
Bustamante, R1
Matos, O1
Huang, L2
Miller, RF1
Vargas, SL1
East, J1
Blanton, LS1
Lim, PL1
Zhou, J1
Ditangco, RA1
Law, MG1
Sirisanthana, T1
Kumarasamy, N1
Chen, YM1
Phanuphak, P1
Lee, CK1
Saphonn, V1
Oka, S1
Zhang, F1
Choi, JY1
Pujari, S1
Kamarulzaman, A1
Li, PC1
Merati, TP1
Yunihastuti, E1
Messerschmidt, L1
Sungkanuparph, S1
Happe, S1
Fischer, A1
Heese, Ch1
Reichelt, D1
Grüneberg, U1
Freund, M1
Kloska, S1
Evers, S1
Husstedt, IW1
Zingale, A1
Carrera, P1
Lazzarin, A2
Scarpellini, P1
James, CW1
McNelis, KC1
Szabo, S1
Kazanjian, PH1
Fisk, D1
Armstrong, W1
Shulin, Q1
Liwei, H1
Ke, Z1
Meshnick, S1
Stroup, JS1
Stephens, JR1
Reust, R1
Miller, JA1
Mitchell, B1
Mahlakwane, MS1
Ramdial, PK1
Sing, Y1
Calonje, E1
Biyana, S1
Katlama, C1
Hoernle, EH1
Reid, TE1
Salmon-Ceron, D1
Fontbonne, A1
Saba, J1
May, T1
Raffi, F1
Chidiac, C1
Patey, O1
Aboulker, JP2
Schwartz, D1
Vildé, JL1
Saah, AJ2
Hoover, DR2
Peng, Y1
Phair, JP1
Visscher, B1
Kingsley, LA1
Schrager, LK1
Podzamczer, D3
Salazar, A1
Jiménez, J2
Consiglio, E1
Santín, M3
Casanova, A2
Rufí, G1
Gudiol, F2
Opravil, M4
Hirschel, B2
Heald, A1
Pechère, M1
Rüttimann, S2
Iten, A1
von Overbeck, J1
Oertle, D1
Praz, G1
Clumeck, N2
Bozzette, SA2
Finkelstein, DM2
Spector, SA3
Frame, P2
Powderly, WG1
He, W1
Phillips, L1
Craven, D1
van der Horst, C2
Feinberg, J3
Bacellar, H1
Phair, J1
Detels, R1
Anderson, R1
Kaslow, RA1
Epstein, LJ1
Meyer, RD1
Antonson, S1
Strigle, SM1
Mohsenifar, Z1
Chalasani, P1
Baffoe-Bonnie, H1
Jurado, RL1
Falloon, J1
Lavelle, J1
Ogata-Arakaki, D1
Byrne, A1
Graziani, A1
Morgan, A1
Amantea, MA1
Ownby, K1
Polis, M1
Davey, RT1
Pastor, C1
Lumbreras, C1
Lizasoain, M1
Oksenhendler, E1
Charreau, I1
Tournerie, C1
Azihary, M1
Carbon, C1
Torres, RA1
Barr, M1
Thorn, M1
Gregory, G1
Kiely, S1
Chanin, E1
Carlo, C1
Martin, M1
Thornton, J1
Tocchetti, A1
Tambini, R1
Allegro, A1
Longoni, E1
Rinaldi, E1
Glatt, AE1
Barnett, ED1
Pelton, SI1
Mirochnick, M3
Cooper, ER1
Walzer, PD1
Foy, J1
Steele, P1
White, M1
Lang, W1
Osmond, D1
Page-Bodkin, K1
Moss, A1
Winkelstein, W1
Stavola, JJ1
Noel, GJ1
Weintrub, PS1
Wara, DW1
Duliege, AM1
Mallolas, J1
Zamora, L1
Gatell, JM1
Miró, JM1
Vernet, E1
Valls, ME1
Soriano, E1
SanMiguel, JG1
Martos, A1
Ferrer, I1
Jorde, UP1
Horowitz, HW2
Wormser, GP2
Girard, PM1
Landman, R1
Gaudebout, C2
Olivares, R1
Saimot, AG1
Jelazko, P1
Certain, A1
Boué, F1
Bouvet, E1
Bolao, F1
Gudiol, GR1
Carlin, EM1
Coker, RJ1
Goldin, RD1
Harris, JR1
Teuscher, AU1
Theiler, R1
Speich, R1
Kuster, H1
Siegenthaler, W1
Russi, EW1
Lüthy, R2
Ioannidis, JP3
Cappelleri, JC1
Skolnik, PR1
Lau, J2
Sacks, HS1
Simonds, RJ1
Hughes, WT1
Navin, TR2
Richards, FO1
Kovacs, JA1
Luft, BJ1
Goebel, FD1
Bogner, JR1
Korraa, H1
Saadeh, C1
Antinori, A3
Murri, R3
Ammassari, A2
De Luca, A2
Linzalone, A1
Cingolani, A1
Damiano, F1
Maiuro, G1
Vecchiet, J1
Scoppettuolo, G1
Safrin, S1
Simpson, G1
Wu, A1
Cheung, T1
Soeiro, R1
Hojczyk, P1
Black, JR1
Weinberg, GA1
Tamburrini, E1
Mencarini, P1
Visconti, E1
Zolfo, M1
Siracusano, A1
Ortona, E1
Sin, DD1
Shafran, SD1
Garavelli, PL1
Gatti, G3
Fioredda, F1
Lorusso, C2
Cruciani, M2
Bassetti, D3
Edge, MD2
Rimland, D3
Bundow, DL1
Aboulafia, DM1
Merighi, M1
Hossein, J1
Travaini, S1
Casazza, R1
Karlsson, M1
Loy, A1
Rossi, G1
Deresinski, SC1
Easterbrook, PJ1
Bucher, HC1
Griffith, L1
Guyatt, GH1
Ruggli, GM1
Weber, R1
Messmer, EP1
Font, RL1
Moll, C1
Bernauer, W1
Kazanjian, P1
Locke, AB1
Hossler, PA1
Lane, BR1
Bartlett, MS1
Smith, JW1
Cannon, M1
Meshnick, SR2
Moorman, AC1
Von Bargen, JC1
Palella, FJ1
Holmberg, SD1
Sackoff, J1
McFarland, J1
Su, S1
Bryan, E1
El-Sadr, WM1
Murphy, RL1
Yurik, TM1
Luskin-Hawk, R1
Cheung, TW1
Balfour, HH1
Eng, R1
Hooton, TM1
Kerkering, TM1
Schutz, M1
Hafner, R2
Payen, MC1
De Wit, S1
Sommereijns, B1
Cook, DE1
Kossey, JL1
Jawahar, DA1
Dama, S1
Miarrostami, R1
Sadagdhar, H1
Anandarao, N1
Koda, RT1
Dubé, MP1
Li, WY1
Chatterjee, DJ1
Stansell, JD1
Sattler, FR1
McIntosh, K2
Cooper, E2
Xu, J2
Lindsey, J2
Jacobus, D2
Mofenson, L2
Yogev, R2
Sullivan, JL2
Sacks, H1
Kovacs, A1
Nachman, S2
Sleasman, J1
Bonagura, V1
McNamara, J1
Dixon, DO1
McIntosh, M1
Albert, JM1
Schnittman, SM1
Patel, SK1
Philpott, JM1
McPartlin, DW1
Saillourglénisson, F1
Chêne, G1
Salmi, LR1
Salamon, R1
Winter, HR1
Wang, Y1
Unadkat, JD1
Gordeuk, VR1
Delanghe, JR1
Langlois, MR1
Boelaert, JR1
Sundar, K1
Rosado-Santos, H1
Reimer, L1
Murray, K1
Michael, J1
Chaloner, K1
Rhame, FS1
Sorvillo, F1
Beall, G1
Turner, PA1
Beer, VL1
Kovacs, AA1
Kerndt, PR1
Dorrell, L1
McCallum, AK1
Snow, MH1
Ong, EL1
Blanchet, KD1
Cheng, B1
Torres, G1
Cadman, J1
Afeltra, J1
Meis, JF1
Mouton, JW1
Verweij, PE1
Capparelli, E1
Bonagura, VR1
Beard, CB1
del Rio, C1
Lee, S1
Pieniazek, NJ1
Carter, JL1
Le, T1
Hightower, A1
Groll, AH1
Ritter, J1
Müller, FM1
Freund, YR1
Dousman, L1
Riccio, ES1
Sato, B1
MacGregor, JT1
Mohagheghpour, N1
Praveen, CV1
Terry, RM1
Elmahallawy, M1
Horsfield, C1
Goldie, SJ1
Kaplan, JE1
Losina, E1
Weinstein, MC1
Paltiel, AD1
Seage, GR1
Craven, DE1
Kimmel, AD1
Zhang, H1
Cohen, CJ1
Freedberg, KA1
Laifer, G1
Slavin, MA1
Hoy, JF1
Stewart, K1
Pettinger, MB1
Lucas, CR1
Kent, SJ1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Trial of Three Anti-Pneumocystis Agents Plus Zidovudine for the Primary Prevention of Serious Infections in Patients With Advanced HIV Infection[NCT00000991]Phase 3600 participants InterventionalCompleted
A Phase III Comparative Study of Dapsone / Trimethoprim and Clindamycin / Primaquine Versus Trimethoprim / Sulfamethoxazole in the Treatment of Mild-to-Moderate PCP in Patients With AIDS[NCT00000640]Phase 3290 participants InterventionalCompleted
A Randomized, Comparative Study of Daily Dapsone and Daily Atovaquone for Prophylaxis Against PCP in HIV-Infected Patients Who Are Intolerant of Trimethoprim and/or Sulfonamides[NCT00000802]Phase 3700 participants InterventionalCompleted
Comparison of Two Dosage Regimens of Oral Dapsone for Prophylaxis of Pneumocystis Carinii Pneumonia in Pediatric HIV Infection[NCT00000739]Phase 196 participants InterventionalCompleted
Effect of Fluconazole, Clarithromycin, and Rifabutin on the Pharmacokinetics of Sulfamethoxazole and Dapsone and Their Hydroxylamine Metabolites[NCT00000826]Phase 148 participants InterventionalCompleted
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

16 reviews available for dapsone and AIDS-Related Opportunistic Infections

ArticleYear
A background and critical analysis of the treatment of pneumocystis carinii pneumonia (PCP) in HIV/AIDS.
    Australian nursing journal (July 1993), 2007, Volume: 14, Issue:9

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Anti-Inflammatory Agents; Antiprotozoa

2007
Human immunodeficiency virus infection in children.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1995, May-01, Volume: 52, Issue:9

    Topics: Adolescent; AIDS-Related Opportunistic Infections; Child; Child, Preschool; Dapsone; Didanosine; Dru

1995
[Current alternatives in the treatment of Pneumocystis carinii pneumonia in patients with AIDS].
    Medicina clinica, 1994, Oct-15, Volume: 103, Issue:12

    Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Atovaquone; Clindamycin; Dapsone; Eflornit

1994
A meta-analysis of the relative efficacy and toxicity of Pneumocystis carinii prophylactic regimens.
    Archives of internal medicine, 1996, Jan-22, Volume: 156, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Dapsone; Dose-Response Relationship, Drug; Humans; Logistic M

1996
Preventing Pneumocystis carinii pneumonia in persons infected with human immunodeficiency virus.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1995, Volume: 21 Suppl 1

    Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antifungal Agents;

1995
Preventing toxoplasmic encephalitis in persons infected with human immunodeficiency virus.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1995, Volume: 21 Suppl 1

    Topics: AIDS-Related Opportunistic Infections; Animals; Anti-Infective Agents; Cats; Dapsone; Drug Therapy,

1995
[Therapy and prevention of pneumocystis carinii pneumonia].
    Der Internist, 1995, Volume: 36, Issue:12

    Topics: AIDS-Related Opportunistic Infections; Animals; Antifungal Agents; Atovaquone; Clindamycin; Clinical

1995
Options in the management of pneumonia caused by Pneumocystis carinii in patients with acquired immune deficiency syndrome and intolerance to trimethoprim/sulfamethoxazole.
    Southern medical journal, 1996, Volume: 89, Issue:3

    Topics: Adrenal Cortex Hormones; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antifungal Ag

1996
Skin involvement with Pneumocystis despite dapsone prophylaxis: a rare cause of skin nodules in a patient with AIDS.
    The American journal of the medical sciences, 1997, Volume: 313, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Dapsone; Dermatomycoses; Humans

1997
Treatment of Pneumocystis carinii pneumonia in adults with AIDS.
    Seminars in respiratory infections, 1997, Volume: 12, Issue:2

    Topics: Administration, Oral; Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antifunga

1997
Meta-analysis of prophylactic treatments against Pneumocystis carinii pneumonia and toxoplasma encephalitis in HIV-infected patients.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1997, Jun-01, Volume: 15, Issue:2

    Topics: Administration, Inhalation; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antifungal

1997
An unusual case of Pneumocystis carinii presenting as an aural mass.
    The Journal of laryngology and otology, 1999, Volume: 113, Issue:6

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Dapsone; Drug Therapy, Combinat

1999
[Effect of dapsone on survival in HIV infected patients: a meta- analysis of finished trials].
    Revue d'epidemiologie et de sante publique, 2000, Volume: 48, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Anti-Inflammatory Agents, Non-S

2000
Iron status and the outcome of HIV infection: an overview.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2001, Volume: 20, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Anti-Infective Agents; be

2001
[Guidelines for Prevention of Pneumocystis carinii Pneumonitis in Children and Adolescents with Cancer].
    Klinische Padiatrie, 2001, Volume: 213 Suppl 1

    Topics: Adolescent; Age Factors; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Anti-Infectiv

2001
Pneumocystis carinii infection in bilateral aural polyps in a human immunodeficiency virus-positive patient.
    The Journal of laryngology and otology, 2002, Volume: 116, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Antifungal Agents; Dapsone; Ear Neoplasms; Ear, Middle

2002

Trials

24 trials available for dapsone and AIDS-Related Opportunistic Infections

ArticleYear
Lower survival in AIDS patients receiving dapsone compared with aerosolized pentamidine for secondary prophylaxis of Pneumocystis carinii pneumonia. Study Group.
    The Journal of infectious diseases, 1995, Volume: 172, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aerosols; AIDS-Related Opportunistic Infections; Dapsone;

1995
Intermittent trimethoprim-sulfamethoxazole compared with dapsone-pyrimethamine for the simultaneous primary prophylaxis of Pneumocystis pneumonia and toxoplasmosis in patients infected with HIV.
    Annals of internal medicine, 1995, May-15, Volume: 122, Issue:10

    Topics: Adult; Aged; AIDS-Related Opportunistic Infections; Dapsone; Drug Administration Schedule; Drug Ther

1995
Once-weekly administration of dapsone/pyrimethamine vs. aerosolized pentamidine as combined prophylaxis for Pneumocystis carinii pneumonia and toxoplasmic encephalitis in human immunodeficiency virus-infected patients.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1995, Volume: 20, Issue:3

    Topics: Administration, Inhalation; Adult; AIDS-Related Opportunistic Infections; Animals; Dapsone; Drug Adm

1995
A randomized trial of three antipneumocystis agents in patients with advanced human immunodeficiency virus infection. NIAID AIDS Clinical Trials Group.
    The New England journal of medicine, 1995, Mar-16, Volume: 332, Issue:11

    Topics: Administration, Oral; Adult; Aerosols; AIDS-Related Opportunistic Infections; CD4 Lymphocyte Count;

1995
Pharmacokinetics and safety of weekly dapsone and dapsone plus pyrimethamine for prevention of pneumocystis pneumonia.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:7

    Topics: Adult; AIDS-Related Opportunistic Infections; Biological Availability; Chromatography, High Pressure

1994
Randomized trial of dapsone and aerosolized pentamidine for the prophylaxis of Pneumocystis carinii pneumonia and toxoplasmic encephalitis.
    The American journal of medicine, 1993, Volume: 95, Issue:6

    Topics: Adult; Aerosols; AIDS-Related Opportunistic Infections; Dapsone; Encephalitis; Female; Humans; Male;

1993
Four different regimens for prevention of Pneumocystis carinii pneumonia and toxoplasma encephalitis in HIV-infected patients.
    AIDS (London, England), 1994, Volume: 8, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Dapsone; Drug Therapy, Combination; Female; Follow-Up

1994
Primary prophylaxis for Pneumocystis carinii pneumonia: a randomized trial comparing cotrimoxazole, aerosolized pentamidine and dapsone plus pyrimethamine.
    AIDS (London, England), 1993, Volume: 7, Issue:1

    Topics: Adult; Aerosols; AIDS-Related Opportunistic Infections; Antifungal Agents; Dapsone; Drug Therapy, Co

1993
Utility of dapsone for prophylaxis of Pneumocystis carinii pneumonia in trimethoprim-sulfamethoxazole-intolerant, HIV-infected individuals.
    AIDS (London, England), 1993, Volume: 7, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; Contraindications; Dapsone; Drug Eruptions; Female; Fe

1993
Dapsone-pyrimethamine compared with aerosolized pentamidine as primary prophylaxis against Pneumocystis carinii pneumonia and toxoplasmosis in HIV infection. The PRIO Study Group.
    The New England journal of medicine, 1993, May-27, Volume: 328, Issue:21

    Topics: Adult; AIDS-Related Complex; AIDS-Related Opportunistic Infections; Dapsone; Drug Combinations; Ence

1993
Thrice-weekly cotrimoxazole is better than weekly dapsone-pyrimethamine for the primary prevention of Pneumocystis carinii pneumonia in HIV-infected patients.
    AIDS (London, England), 1993, Volume: 7, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Dapsone; Drug Administration Schedule; Drug Therapy, C

1993
Aerosolized pentamidine, cotrimoxazole and dapsone-pyrimethamine for primary prophylaxis of Pneumocystis carinii pneumonia and toxoplasmic encephalitis.
    AIDS (London, England), 1995, Volume: 9, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Animals; Anti-Infe

1995
Comparison of three regimens for treatment of mild to moderate Pneumocystis carinii pneumonia in patients with AIDS. A double-blind, randomized, trial of oral trimethoprim-sulfamethoxazole, dapsone-trimethoprim, and clindamycin-primaquine. ACTG 108 Study
    Annals of internal medicine, 1996, May-01, Volume: 124, Issue:9

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Clindamycin; Dapsone; Double-Blind Met

1996
Alternative dapsone dosage regimen for prophylaxis of Pneumocystis carinii pneumonia.
    The Pediatric infectious disease journal, 1996, Volume: 15, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antiviral Agents; Child; Child, Presch

1996
Low-dose dapsone, co-trimoxazole, and survival in Pneumocystis carinii primary prophylaxis.
    AIDS (London, England), 1996, Volume: 10, Issue:9

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Dapsone; Drug Therapy, Combination; Hu

1996
Population pharmacokinetics of dapsone administered biweekly to human immunodeficiency virus-infected patients.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:12

    Topics: Adult; AIDS-Related Opportunistic Infections; Analysis of Variance; Anti-Infective Agents; Antibioti

1996
Prophylaxis for opportunistic infections among HIV-infected patients receiving medical care.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1998, Dec-01, Volume: 19, Issue:4

    Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Analysis of Variance; Anti-Infective Agent

1998
Atovaquone compared with dapsone for the prevention of Pneumocystis carinii pneumonia in patients with HIV infection who cannot tolerate trimethoprim, sulfonamides, or both. Community Program for Clinical Research on AIDS and the AIDS Clinical Trials Grou
    The New England journal of medicine, 1998, Dec-24, Volume: 339, Issue:26

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Atovaquone; Dapsone; Female; Fo

1998
A controlled trial of dapsone versus pyrimethamine-sulfadoxine for primary prophylaxis of Pneumocystis carinii pneumonia and toxoplasmosis in patients with AIDS.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1997, Volume: 51, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; AIDS-Related Opportunistic Infections; Anti-Infecti

1997
Pharmacokinetics of trimetrexate and dapsone in AIDS patients with Pneumocystis carinii pneumonia.
    Journal of clinical pharmacology, 1999, Volume: 39, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; Analysis of Variance; Anti-Infective Agents; Area Unde

1999
Toxicity and efficacy of daily vs. weekly dapsone for prevention of Pneumocystis carinii pneumonia in children infected with human immunodeficiency virus. ACTG 179 Study Team. AIDS Clinical Trials Group.
    The Pediatric infectious disease journal, 1999, Volume: 18, Issue:5

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Child; Child, Preschool; Dapsone; Drug

1999
Population pharmacokinetics of dapsone in children with human immunodeficiency virus infection.
    Clinical pharmacology and therapeutics, 2001, Volume: 70, Issue:1

    Topics: Adolescent; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antibiotics, Antitubercula

2001
[Successful treatment of HIV-associated pneumocystis carinii pneumonia with dapsone plus trimethoprim].
    Wiener klinische Wochenschrift, 1992, Volume: 104, Issue:18

    Topics: Administration, Oral; Adult; AIDS-Related Opportunistic Infections; Ambulatory Care; Dapsone; Dose-R

1992
Oral dapsone versus nebulized pentamidine for Pneumocystis carinii pneumonia prophylaxis: an open randomized prospective trial to assess efficacy and haematological toxicity.
    AIDS (London, England), 1992, Volume: 6, Issue:10

    Topics: Administration, Intranasal; Administration, Oral; Adult; AIDS-Related Opportunistic Infections; Bloo

1992

Other Studies

59 other studies available for dapsone and AIDS-Related Opportunistic Infections

ArticleYear
Acute generalised exanthematous pustulosis induced by Pneumocystis jirovecii pneumonia prophylaxis with dapsone.
    International journal of STD & AIDS, 2013, Volume: 24, Issue:9

    Topics: Acute Generalized Exanthematous Pustulosis; Adult; AIDS-Related Opportunistic Infections; Anti-Infec

2013
High Prevalence of Pneumocystis jirovecii Dihydropteroate Synthase Gene Mutations in Patients with a First Episode of Pneumocystis Pneumonia in Santiago, Chile, and Clinical Response to Trimethoprim-Sulfamethoxazole Therapy.
    Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; AIDS-Related Opportunistic Infections; Caspofungin; Chil

2017
Symptomatic hyperbilirubinemia secondary to dapsone-induced hemolysis and atazanavir therapy.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Anemia, Hemolytic; Anti-HIV Agents; Anti-Infective Age

2012
Failure to prescribe pneumocystis prophylaxis is associated with increased mortality, even in the cART era: results from the Treat Asia HIV observational database.
    Journal of the International AIDS Society, 2012, Jan-26, Volume: 15, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antifungal Agents; Asia; CD4 Lymphocy

2012
[HIV-associated cerebral toxoplasmosis -- review and retrospective analysis of 36 patients].
    Der Nervenarzt, 2002, Volume: 73, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; AIDS-Related Opportunistic Infections; Antiretrovir

2002
Detection of Pneumocystis carinii and characterization of mutations associated with sulfa resistance in bronchoalveolar lavage samples from human immunodeficiency virus-infected subjects.
    Journal of clinical microbiology, 2003, Volume: 41, Issue:6

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Bronchoalveolar Lavage Fluid; Dapsone;

2003
Reinstituting trimethoprim--sulfamethoxazole in patients receiving atovaquone for Pneumocystis carinii pneumonia prophylaxis.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2003, Aug-01, Volume: 60, Issue:15

    Topics: AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Atovaquone; Clinical Protocols; Dapson

2003
Increase in prevalence of Pneumocystis carinii mutations in patients with AIDS and P. carinii pneumonia, in the United States and China.
    The Journal of infectious diseases, 2004, May-01, Volume: 189, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Anti-Infective Age

2004
Adverse reactions associated with dapsone therapy in HIV-positive patients: a case presentation and review.
    The AIDS reader, 2006, Volume: 16, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Dapsone; Drug Hypersensitivity;

2006
Otic pneumocystosis in acquired immune deficiency syndrome.
    The American journal of surgical pathology, 2008, Volume: 32, Issue:7

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Dapsone; Drug Therapy, Combinat

2008
[The impact of the prevention of cerebral toxoplasmosis].
    Journal of neuroradiology = Journal de neuroradiologie, 1995, Volume: 22, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antiprotozoal Agents; Brain Abs

1995
Drugs for AIDS and associated infections.
    The Medical letter on drugs and therapeutics, 1995, Oct-13, Volume: 37, Issue:959

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Amphotericin B; Antifunga

1995
Prevention and treatment of Pneumocystis carinii pneumonia in patients infected with HIV.
    Drug and therapeutics bulletin, 1994, Feb-17, Volume: 32, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Dapsone; Drug Therapy, Combination; Fees, Pharmaceutic

1994
Predictors for failure of Pneumocystis carinii pneumonia prophylaxis. Multicenter AIDS Cohort Study.
    JAMA, 1995, Apr-19, Volume: 273, Issue:15

    Topics: Adult; AIDS-Related Opportunistic Infections; CD4 Lymphocyte Count; Dapsone; HIV Infections; HIV-1;

1995
Primary prophylaxis against opportunistic infections in patients with AIDS.
    The New England journal of medicine, 1995, Mar-16, Volume: 332, Issue:11

    Topics: AIDS-Related Opportunistic Infections; Clotrimazole; Dapsone; Fluconazole; Humans; Mycoses; Pentamid

1995
Clinical manifestations of AIDS in the era of pneumocystis prophylaxis. Multicenter AIDS Cohort Study.
    The New England journal of medicine, 1993, Dec-23, Volume: 329, Issue:26

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Candidiasis; CD4-Positive

1993
Persistence of Pneumocystis carinii in patients with AIDS receiving chemoprophylaxis.
    American journal of respiratory and critical care medicine, 1994, Volume: 150, Issue:5 Pt 1

    Topics: Adult; AIDS-Related Opportunistic Infections; Bronchoalveolar Lavage Fluid; Dapsone; Humans; Male; M

1994
Dapsone therapy causing sulfone syndrome and lethal hepatic failure in an HIV-infected patient.
    Southern medical journal, 1994, Volume: 87, Issue:11

    Topics: Adult; AIDS-Related Opportunistic Infections; Chemical and Drug Induced Liver Injury; Dapsone; Drug

1994
Toxoplasma gondii infection in advanced HIV infection.
    AIDS (London, England), 1994, Volume: 8, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Dapsone; Encephalitis; Female; Humans; Male; Middle Ag

1994
Dilemmas in the prophylaxis of Pneumocystis carinii pneumonia.
    Southern medical journal, 1994, Volume: 87, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Clindamycin; Dapso

1994
Dapsone for prevention of Pneumocystis pneumonia in children with acquired immunodeficiency syndrome.
    The Pediatric infectious disease journal, 1994, Volume: 13, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Child; Dapsone; Female; Humans; Infant; Pneumonia, Pne

1994
Synergistic combinations of Ro 11-8958 and other dihydrofolate reductase inhibitors with sulfamethoxazole and dapsone for therapy of experimental pneumocystosis.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:7

    Topics: AIDS-Related Opportunistic Infections; Animals; Dapsone; Disease Models, Animal; Dose-Response Relat

1993
Population-based estimates of antiretroviral therapy and anti-Pneumocystis prophylaxis in San Francisco: 1991.
    Journal of acquired immune deficiency syndromes, 1993, Volume: 6, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antiviral Agents; Cohort Studies; Daps

1993
Efficacy and safety of dapsone prophylaxis against Pneumocystis carinii pneumonia in human immunodeficiency virus-infected children.
    The Pediatric infectious disease journal, 1993, Volume: 12, Issue:8

    Topics: Adolescent; AIDS-Related Opportunistic Infections; Child; Child, Preschool; Dapsone; Humans; Infant;

1993
Failure of intravenous pentamidine prophylaxis for Pneumocystis carinii pneumonia.
    The Journal of pediatrics, 1993, Volume: 122, Issue:1

    Topics: Administration, Inhalation; Aerosols; AIDS-Related Opportunistic Infections; Child, Preschool; Dapso

1993
Hepatic and pulmonary pneumocystosis during primary prophylaxis for Pneumocystis carinii pneumonia with dapsone/pyrimethamine.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1993, Volume: 16, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Dapsone; Drug Therapy, Combination; Humans; Liver Dise

1993
Systemic Pneumocystis carinii pneumonia prophylaxis with dapsone and pyrimethamine fails to protect against extrapulmonary pneumocystosis.
    Genitourinary medicine, 1993, Volume: 69, Issue:2

    Topics: Administration, Inhalation; Adult; AIDS-Related Opportunistic Infections; Dapsone; Drug Therapy, Com

1993
Predictive value of bronchoalveolar lavage in excluding a diagnosis of Pneumocystis carinii pneumonia during prophylaxis with aerosolized pentamidine.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1993, Volume: 16, Issue:4

    Topics: Administration, Intranasal; Adult; Aerosols; AIDS-Related Opportunistic Infections; Bronchoalveolar

1993
Iron overload as a mechanism for the lowered survival in AIDS patients receiving dapsone-iron protoxalate for secondary prophylaxis of Pneumocystis carinii pneumonia.
    The Journal of infectious diseases, 1996, Volume: 174, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Da

1996
Imbalance between Pneumocystis carinii cysts and trophozoites in bronchoalveolar lavage fluid from patients with pneumocystosis receiving prophylaxis.
    Journal of medical microbiology, 1996, Volume: 45, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antifungal Agents; Bronchoalveo

1996
Dapsone- and primaquine-induced methemoglobinemia in HIV-infected individuals.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1996, Aug-15, Volume: 12, Issue:5

    Topics: Adult; AIDS-Related Opportunistic Infections; Anemia, Hemolytic; Anti-Infective Agents; Clindamycin;

1996
[Dapsone in the prevention of HIV-related parasitosis].
    Recenti progressi in medicina, 1996, Volume: 87, Issue:6

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiparasitic Agents; Dapsone; Drug Therapy, Combinati

1996
Does dapsone increase mortality when given for prophylaxis of Pneumocystis carinii pneumonia?
    AIDS (London, England), 1996, Volume: 10, Issue:9

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Dapsone; Humans; Pneumonia, Pneumocyst

1996
Community-acquired bacteremia in HIV-positive patients: protective benefit of co-trimoxazole.
    AIDS (London, England), 1996, Volume: 10, Issue:14

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Bacteremia; Community-Acquired

1996
Penetration of dapsone into lung of human immunodeficiency virus-infected children.
    The Pediatric infectious disease journal, 1997, Volume: 16, Issue:5

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Bronchoalveolar Lavage Fluid; Bronchos

1997
How to interpret an overview: a meta-analysis of the relative efficacy and toxicity of Pneumocystis carinii prophylactic regimens.
    Genitourinary medicine, 1997, Volume: 73, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Clinical Trials as Topic; Dapsone; Dat

1997
Pneumocystis carinii infection of the conjunctiva in a patient with acquired immune deficiency syndrome.
    Ophthalmology, 1997, Volume: 104, Issue:11

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Conjunctiva; Conjunctival Disea

1997
Pneumocystis carinii mutations associated with sulfa and sulfone prophylaxis failures in AIDS patients.
    AIDS (London, England), 1998, May-28, Volume: 12, Issue:8

    Topics: Adolescent; Adult; Aged; AIDS-Related Opportunistic Infections; Amino Acid Sequence; Anti-Infective

1998
Pneumocystis carinii pneumonia incidence and chemoprophylaxis failure in ambulatory HIV-infected patients. HIV Outpatient Study (HOPS) Investigators.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1998, Oct-01, Volume: 19, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Ambulatory Care; Anti-Infective Agents; Antifungal Age

1998
Heterogeneity of the baseline risk within patient populations of clinical trials: a proposed evaluation algorithm.
    American journal of epidemiology, 1998, Dec-01, Volume: 148, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Algorithms; Anti-HIV Agen

1998
Successful desensitization to dapsone for Pneumocystis carinii prophylaxis in an HIV-positive patient.
    The Annals of pharmacotherapy, 1998, Volume: 32, Issue:12

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Dapsone; Desensitization, Immun

1998
Bilateral upper-lobe cavitary Pneumocystis carinii pneumonia in a patient on dapsone prophylaxis.
    The American journal of the medical sciences, 1999, Volume: 317, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Dapsone; Diagnosis, Differential; Huma

1999
Atovaquone compared with dapsone to prevent Pneumocystis carinii pneumonia.
    The New England journal of medicine, 1999, May-13, Volume: 340, Issue:19

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Atovaquone; Dapsone; Drug Costs; HIV I

1999
Relationship between event rates and treatment effects in clinical site differences within multicenter trials: an example from primary Pneumocystis carinii prophylaxis.
    Controlled clinical trials, 1999, Volume: 20, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Controlled Clinical Trials as Topic; D

1999
Reasons for failure of prophylaxis for Pneumocystis carinii pneumonia.
    AIDS (London, England), 1999, May-28, Volume: 13, Issue:8

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antifungal Agents; Dapsone; Humans; Pe

1999
Drug-resistant Pneumocystis carinii.
    Lancet (London, England), 1999, Oct-16, Volume: 354, Issue:9187

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Dapsone; Dihydropteroate Synthase; Dru

1999
CYP2C8/9 mediate dapsone N-hydroxylation at clinical concentrations of dapsone.
    Drug metabolism and disposition: the biological fate of chemicals, 2000, Volume: 28, Issue:8

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Aryl Hydrocarbon Hydroxylases; Catalys

2000
Unusual presentation of thoracic Pneumocystis carinii infection in a patient with acquired immunodeficiency syndrome.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2001, Feb-01, Volume: 32, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Biopsy; Dapsone; Diagnosis, Dif

2001
Quantifying and documenting prior beliefs in clinical trials.
    Statistics in medicine, 2001, Feb-28, Volume: 20, Issue:4

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antifungal Agents; Atovaquone; Attitud

2001
Incidence and determinants of Pseudomonas aeruginosa infection among persons with HIV: association with hospital exposure.
    American journal of infection control, 2001, Volume: 29, Issue:2

    Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Azithromycin; CD4 L

2001
Dapsone/pyrimethamine versus aerosolized pentamidine as prophylaxis against PCP in HIV infection.
    AIDS patient care, 1995, Volume: 9, Issue:5

    Topics: Adult; Aerosols; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Anti-Infective Agents

1995
Current management practices in the treatment of Pneumocystis carinii pneumonia (PCP).
    AIDS patient care and STDs, 1996, Volume: 10, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Algorithms; Anti-Infective Agents; Antifungal Agents; Dapsone

1996
Preventing opportunistic infections.
    PI perspective, 1995, Issue:no 16

    Topics: Acyclovir; AIDS-Related Opportunistic Infections; Clarithromycin; Clindamycin; Clinical Trials as To

1995
Optimizing PCP therapy.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1997, Volume: 11, Issue:10

    Topics: Aerosols; AIDS-Related Opportunistic Infections; Antifungal Agents; Atovaquone; CD4 Lymphocyte Count

1997
Adherence to PCP medications found to be low.
    TreatmentUpdate, 1998, Volume: 10, Issue:7

    Topics: AIDS-Related Opportunistic Infections; Dapsone; Humans; Patient Compliance; Pneumonia, Pneumocystis;

1998
Prevention of invasive aspergillosis in AIDS by sulfamethoxazole.
    AIDS (London, England), 2001, May-25, Volume: 15, Issue:8

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Aspergillosis; Aspergillus flavus; Asp

2001
Effect of mutations in Pneumocystis carinii dihydropteroate synthase gene on outcome of P carinii pneumonia in patients with HIV-1: a prospective study.
    Lancet (London, England), 2001, Aug-18, Volume: 358, Issue:9281

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Dapsone; Dihydropteroate Syntha

2001
Immunohematotoxicity studies with combinations of dapsone and zidovudine.
    International immunopharmacology, 2001, Volume: 1, Issue:12

    Topics: AIDS-Related Opportunistic Infections; Anemia; Animals; Anti-HIV Agents; Antiprotozoal Agents; Bone

2001
Prophylaxis for human immunodeficiency virus-related Pneumocystis carinii pneumonia: using simulation modeling to inform clinical guidelines.
    Archives of internal medicine, 2002, Apr-22, Volume: 162, Issue:8

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antiprotozoal Agents; Atovaquone; CD4

2002