dapi has been researched along with Trypanosomiasis, African in 2 studies
DAPI: RN given refers to parent cpd.
Trypanosomiasis, African: A disease endemic among people and animals in Central Africa. It is caused by various species of trypanosomes, particularly T. gambiense and T. rhodesiense. Its second host is the TSETSE FLY. Involvement of the central nervous system produces African sleeping sickness. Nagana is a rapidly fatal trypanosomiasis of horses and other animals.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The DAPI structure has been modified by replacing the phenyl group with substituted phenyl or heteroaryl rings." | 1.46 | Exploration of DAPI analogues: Synthesis, antitrypanosomal activity, DNA binding and fluorescence properties. ( Boykin, DW; Brun, R; Farahat, AA; Kumar, A; Paul, A; Say, M; Wenzler, T; Wilson, WD, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Farahat, AA | 1 |
| Kumar, A | 1 |
| Say, M | 1 |
| Wenzler, T | 1 |
| Brun, R | 1 |
| Paul, A | 1 |
| Wilson, WD | 1 |
| Boykin, DW | 1 |
| Borowy, NK | 1 |
| Fink, E | 1 |
| Hirumi, H | 1 |
2 other studies available for dapi and Trypanosomiasis, African
| Article | Year |
|---|---|
Exploration of DAPI analogues: Synthesis, antitrypanosomal activity, DNA binding and fluorescence properties.
Topics: Animals; Circular Dichroism; Disease Models, Animal; DNA; Fluorescence; Indoles; Mice; Molecular Str | 2017 |
In vitro activity of the trypanocidal diamidine DAPI on animal-infective Trypanosoma brucei brucei.
Topics: Animals; Cattle; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Indoles; Mice; Mice, In | 1985 |