dapi has been researched along with Tauopathies in 2 studies
DAPI: RN given refers to parent cpd.
Tauopathies: Neurodegenerative disorders involving deposition of abnormal tau protein isoforms (TAU PROTEINS) in neurons and glial cells in the brain. Pathological aggregations of tau proteins are associated with mutation of the tau gene on chromosome 17 in patients with ALZHEIMER DISEASE; DEMENTIA; PARKINSONIAN DISORDERS; progressive supranuclear palsy (SUPRANUCLEAR PALSY, PROGRESSIVE); and corticobasal degeneration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "DAPI was positive in 3R/4R (3-repeat/4-repeat) tau deposits in Alzheimer's disease, myotonic dystrophy, and neurodegeneration with brain iron accumulation, and in 4R tau deposits in corticobasal degeneration, but negative in 4R tau deposits in frontotemporal dementia with parkinsonism-17 and progressive supranuclear palsy." | 1.48 | 4',6-Diamidino-2-Phenylindole Distinctly Labels Tau Deposits. ( Kinoshita, E; Li, C; Maruyama, H; Matsubara, T; Matsumoto, M; Shrestha, T; Takahashi, T, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, C | 1 |
| Takahashi, T | 1 |
| Shrestha, T | 1 |
| Kinoshita, E | 1 |
| Matsubara, T | 1 |
| Matsumoto, M | 1 |
| Maruyama, H | 1 |
| Fox, LM | 1 |
| William, CM | 1 |
| Adamowicz, DH | 1 |
| Pitstick, R | 1 |
| Carlson, GA | 1 |
| Spires-Jones, TL | 1 |
| Hyman, BT | 1 |
2 other studies available for dapi and Tauopathies
| Article | Year |
|---|---|
4',6-Diamidino-2-Phenylindole Distinctly Labels Tau Deposits.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain; Fluorescent Dyes; Frontotemporal Dementia; Humans | 2018 |
Soluble tau species, not neurofibrillary aggregates, disrupt neural system integration in a tau transgenic model.
Topics: Animals; Animals, Genetically Modified; Cell Count; Cytoskeletal Proteins; Disease Models, Animal; D | 2011 |