dapi has been researched along with Parkinson Disease in 7 studies
DAPI: RN given refers to parent cpd.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| "DAPI was positive in 3R/4R (3-repeat/4-repeat) tau deposits in Alzheimer's disease, myotonic dystrophy, and neurodegeneration with brain iron accumulation, and in 4R tau deposits in corticobasal degeneration, but negative in 4R tau deposits in frontotemporal dementia with parkinsonism-17 and progressive supranuclear palsy." | 1.48 | 4',6-Diamidino-2-Phenylindole Distinctly Labels Tau Deposits. ( Kinoshita, E; Li, C; Maruyama, H; Matsubara, T; Matsumoto, M; Shrestha, T; Takahashi, T, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, C | 1 |
| Takahashi, T | 1 |
| Shrestha, T | 1 |
| Kinoshita, E | 1 |
| Matsubara, T | 1 |
| Matsumoto, M | 1 |
| Maruyama, H | 1 |
| Wang, Y | 1 |
| Qu, L | 1 |
| Wang, XL | 1 |
| Gao, L | 1 |
| Li, ZZ | 1 |
| Gao, GD | 1 |
| Yang, Q | 1 |
| Angelova, PR | 1 |
| Agrawalla, BK | 1 |
| Elustondo, PA | 1 |
| Gordon, J | 1 |
| Shiba, T | 1 |
| Abramov, AY | 1 |
| Chang, YT | 1 |
| Pavlov, EV | 1 |
| Gerard, M | 1 |
| Deleersnijder, A | 1 |
| Daniëls, V | 1 |
| Schreurs, S | 1 |
| Munck, S | 1 |
| Reumers, V | 1 |
| Pottel, H | 1 |
| Engelborghs, Y | 1 |
| Van den Haute, C | 1 |
| Taymans, JM | 1 |
| Debyser, Z | 1 |
| Baekelandt, V | 1 |
| Hu, X | 1 |
| Weng, Z | 1 |
| Chu, CT | 1 |
| Zhang, L | 1 |
| Cao, G | 1 |
| Gao, Y | 1 |
| Signore, A | 1 |
| Zhu, J | 1 |
| Hastings, T | 1 |
| Greenamyre, JT | 1 |
| Chen, J | 1 |
| Tsuchiya, K | 1 |
| Tajima, H | 1 |
| Kuwae, T | 1 |
| Takeshima, T | 1 |
| Nakano, T | 1 |
| Tanaka, M | 1 |
| Sunaga, K | 1 |
| Fukuhara, Y | 1 |
| Nakashima, K | 1 |
| Ohama, E | 1 |
| Mochizuki, H | 1 |
| Mizuno, Y | 1 |
| Katsube, N | 1 |
| Ishitani, R | 1 |
| Daily, D | 1 |
| Barzilai, A | 1 |
| Offen, D | 1 |
| Kamsler, A | 1 |
| Melamed, E | 1 |
| Ziv, I | 1 |
7 other studies available for dapi and Parkinson Disease
| Article | Year |
|---|---|
4',6-Diamidino-2-Phenylindole Distinctly Labels Tau Deposits.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain; Fluorescent Dyes; Frontotemporal Dementia; Humans | 2018 |
Firing pattern modulation through SK channel current increase underlies neuronal survival in an organotypic slice model of Parkinson's disease.
Topics: Action Potentials; Animals; Calcium; Cell Death; Cell Survival; Disease Models, Animal; Dopaminergic | 2015 |
In situ investigation of mammalian inorganic polyphosphate localization using novel selective fluorescent probes JC-D7 and JC-D8.
Topics: Animals; Astrocytes; Benzimidazoles; Brain; Cells, Cultured; Dimethyl Sulfoxide; Disease Models, Ani | 2014 |
Inhibition of FK506 binding proteins reduces alpha-synuclein aggregation and Parkinson's disease-like pathology.
Topics: Age Factors; alpha-Synuclein; Animals; Apoptosis; Cells, Cultured; Corpus Striatum; Disease Models, | 2010 |
Peroxiredoxin-2 protects against 6-hydroxydopamine-induced dopaminergic neurodegeneration via attenuation of the apoptosis signal-regulating kinase (ASK1) signaling cascade.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Animals; Apomorphine; Brain; Cell Differentiation; Ce | 2011 |
Pro-apoptotic protein glyceraldehyde-3-phosphate dehydrogenase promotes the formation of Lewy body-like inclusions.
Topics: Acetates; Aged; Aged, 80 and over; alpha-Synuclein; Animals; beta-Synuclein; Blotting, Western; Brai | 2005 |
The involvement of p53 in dopamine-induced apoptosis of cerebellar granule neurons and leukemic cells overexpressing p53.
Topics: Animals; Apoptosis; Cell Nucleus; Cerebellum; DNA; DNA Damage; DNA Fragmentation; Dopamine; Fluoresc | 1999 |