Page last updated: 2024-10-25

dapi and Nerve Degeneration

dapi has been researched along with Nerve Degeneration in 19 studies

DAPI: RN given refers to parent cpd.

Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.

Research Excerpts

ExcerptRelevanceReference
"When DAPI was injected intraocularly instead of being applied to the optic tract, a regular mosaic of neurons in the ganglion cell layer was selectively stained, and two bands of fluorescence were observed in the inner plexiform layer, at the level where two bands of radioactive acetylcholine were observed in radioautographs."1.27Acetylcholine-synthesizing amacrine cells: identification and selective staining by using radioautography and fluorescent markers. ( Hayden, SA; Masland, RH; Mills, JW, 1984)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.26)18.7374
1990's1 (5.26)18.2507
2000's10 (52.63)29.6817
2010's7 (36.84)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Orita, S1
Henry, K1
Mantuano, E1
Yamauchi, K1
De Corato, A1
Ishikawa, T1
Feltri, ML1
Wrabetz, L1
Gaultier, A1
Pollack, M1
Ellisman, M1
Takahashi, K1
Gonias, SL1
Campana, WM1
García-García, L1
Delgado, M1
Al-Sayed, AA1
Bascuñana, P1
Fernández de la Rosa, R1
Bermejo-Bescós, P1
Martín-Aragón, S1
Pozo, MA1
Hanstein, R1
Lu, A1
Wurst, W1
Holsboer, F1
Deussing, JM1
Clement, AB1
Behl, C1
Li, L1
Rasul, I1
Liu, J1
Zhao, B1
Tang, R1
Premont, RT1
Suo, WZ1
Zhao, LC1
Yang, B1
Wang, R1
Lipton, SA1
Zhang, D1
Bailey, JA1
Lahiri, DK1
Böttger, D1
Ullrich, C1
Humpel, C1
Gerard, M1
Deleersnijder, A1
Daniëls, V1
Schreurs, S1
Munck, S1
Reumers, V1
Pottel, H1
Engelborghs, Y1
Van den Haute, C1
Taymans, JM1
Debyser, Z1
Baekelandt, V1
Lim, Y1
Kehm, VM1
Lee, EB1
Soper, JH1
Li, C1
Trojanowski, JQ1
Lee, VM1
Daniel, B1
DeCoster, MA1
Schmued, LC1
Stowers, CC1
Scallet, AC1
Xu, L1
Soares, S1
Traka, M1
von Boxberg, Y1
Bouquet, C1
Karagogeos, D1
Nothias, F1
Abou-Sleymane, G1
Chalmel, F1
Helmlinger, D1
Lardenois, A1
Thibault, C1
Weber, C1
Mérienne, K1
Mandel, JL1
Poch, O1
Devys, D1
Trottier, Y1
Leschik, J1
Welzel, A1
Weissmann, C1
Eckert, A1
Brandt, R1
Park, SS1
Schulz, EM1
Lee, D1
Bigbee, AJ1
Hoang, TX1
Havton, LA1
Lei, Y1
Garrahan, N1
Hermann, B1
Becker, DL1
Hernandez, MR1
Boulton, ME1
Morgan, JE1
Masland, RH1
Mills, JW1
Hayden, SA1
Isenmann, S1
Bähr, M1

Other Studies

19 other studies available for dapi and Nerve Degeneration

ArticleYear
Schwann cell LRP1 regulates remak bundle ultrastructure and axonal interactions to prevent neuropathic pain.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Mar-27, Volume: 33, Issue:13

    Topics: Actins; Analysis of Variance; Animals; Axons; CD11b Antigen; Cytoplasm; Disease Models, Animal; Gene

2013
In vivo [¹⁸F] FDG PET imaging reveals that p-chloroamphetamine neurotoxicity is associated with long-term cortical and hippocampal hypometabolism.
    Molecular imaging and biology, 2015, Volume: 17, Issue:2

    Topics: Animals; Autoradiography; Fluoresceins; Fluorodeoxyglucose F18; Glial Fibrillary Acidic Protein; Glu

2015
Transgenic overexpression of corticotropin releasing hormone provides partial protection against neurodegeneration in an in vivo model of acute excitotoxic stress.
    Neuroscience, 2008, Oct-15, Volume: 156, Issue:3

    Topics: Analysis of Variance; Animals; Brain-Derived Neurotrophic Factor; Cell Death; Corticotropin-Releasin

2008
Augmented axonal defects and synaptic degenerative changes in female GRK5 deficient mice.
    Brain research bulletin, 2009, Mar-16, Volume: 78, Issue:4-5

    Topics: Alzheimer Disease; Animals; Axons; Blotting, Western; Disease Models, Animal; Female; Fluoroimmunoas

2009
Type C botulinum toxin causes degeneration of motoneurons in vivo.
    Neuroreport, 2010, Jan-06, Volume: 21, Issue:1

    Topics: Animals; Botulinum Toxins; Cell Count; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Ma

2010
A novel effect of rivastigmine on pre-synaptic proteins and neuronal viability in a neurodegeneration model of fetal rat primary cortical cultures and its implication in Alzheimer's disease.
    Journal of neurochemistry, 2010, Volume: 112, Issue:4

    Topics: Actins; Adenosine Triphosphate; Alzheimer Disease; Animals; Cell Enlargement; Cell Survival; Cells,

2010
Monocytes deliver bioactive nerve growth factor through a brain capillary endothelial cell-monolayer in vitro and counteract degeneration of cholinergic neurons.
    Brain research, 2010, Feb-02, Volume: 1312

    Topics: Animals; Animals, Newborn; Brain; Cell Adhesion; Cell Movement; Cells, Cultured; Choline O-Acetyltra

2010
Inhibition of FK506 binding proteins reduces alpha-synuclein aggregation and Parkinson's disease-like pathology.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Feb-17, Volume: 30, Issue:7

    Topics: Age Factors; alpha-Synuclein; Animals; Apoptosis; Cells, Cultured; Corpus Striatum; Disease Models,

2010
α-Syn suppression reverses synaptic and memory defects in a mouse model of dementia with Lewy bodies.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Jul-06, Volume: 31, Issue:27

    Topics: Acoustic Stimulation; Age Factors; alpha-Synuclein; Analysis of Variance; Animals; Animals, Newborn;

2011
Quantification of sPLA2-induced early and late apoptosis changes in neuronal cell cultures using combined TUNEL and DAPI staining.
    Brain research. Brain research protocols, 2004, Volume: 13, Issue:3

    Topics: Animals; Apoptosis; Biological Assay; Cell Nucleus; Cell Shape; Cells, Cultured; Coloring Agents; Fe

2004
Fluoro-Jade C results in ultra high resolution and contrast labeling of degenerating neurons.
    Brain research, 2005, Feb-21, Volume: 1035, Issue:1

    Topics: Animals; Astrocytes; Brain; Fluoresceins; Fluorescent Dyes; Glial Fibrillary Acidic Protein; Immunoh

2005
Neuronal and glial expression of the adhesion molecule TAG-1 is regulated after peripheral nerve lesion or central neurodegeneration of adult nervous system.
    The European journal of neuroscience, 2005, Volume: 21, Issue:5

    Topics: Animals; Animals, Newborn; Blotting, Western; Cell Adhesion Molecules, Neuronal; Cells, Cultured; Co

2005
Polyglutamine expansion causes neurodegeneration by altering the neuronal differentiation program.
    Human molecular genetics, 2006, Mar-01, Volume: 15, Issue:5

    Topics: Animals; Blotting, Western; Cell Differentiation; Fluorescent Antibody Technique, Indirect; Fluoresc

2006
Inverse and distinct modulation of tau-dependent neurodegeneration by presenilin 1 and amyloid-beta in cultured cortical neurons: evidence that tau phosphorylation is the limiting factor in amyloid-beta-induced cell death.
    Journal of neurochemistry, 2007, Volume: 101, Issue:5

    Topics: Amyloid beta-Peptides; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Embryo, Mammalian; Gre

2007
Disruption of dopamine homeostasis underlies selective neurodegeneration mediated by alpha-synuclein.
    The European journal of neuroscience, 2007, Volume: 26, Issue:11

    Topics: Alanine; alpha-Methyltyrosine; alpha-Synuclein; Animals; Animals, Genetically Modified; Cells, Cultu

2007
Reimplantation of avulsed lumbosacral ventral roots in the rat ameliorates injury-induced degeneration of primary afferent axon collaterals in the spinal dorsal columns.
    Neuroscience, 2008, Mar-18, Volume: 152, Issue:2

    Topics: Animals; Calcium-Binding Proteins; Cauda Equina; Disease Models, Animal; Female; Functional Laterali

2008
Quantification of retinal transneuronal degeneration in human glaucoma: a novel multiphoton-DAPI approach.
    Investigative ophthalmology & visual science, 2008, Volume: 49, Issue:5

    Topics: Aged; Aged, 80 and over; Algorithms; Cell Count; Cell Nucleus; Fluorescent Dyes; Glaucoma, Open-Angl

2008
Acetylcholine-synthesizing amacrine cells: identification and selective staining by using radioautography and fluorescent markers.
    Proceedings of the Royal Society of London. Series B, Biological sciences, 1984, Nov-22, Volume: 223, Issue:1230

    Topics: Acetylcholine; Animals; Autoradiography; Axonal Transport; Axons; Choline; Efferent Pathways; Fluore

1984
Expression of c-Jun protein in degenerating retinal ganglion cells after optic nerve lesion in the rat.
    Experimental neurology, 1997, Volume: 147, Issue:1

    Topics: Animals; Apoptosis; DNA Damage; Female; Fluorescent Dyes; Genetic Techniques; Immunohistochemistry;

1997