Page last updated: 2024-10-25

dapi and Melanoma

dapi has been researched along with Melanoma in 6 studies

DAPI: RN given refers to parent cpd.

Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)

Research Excerpts

ExcerptRelevanceReference
"Among 20 Spitz nevi examined, 18 of them showed a diploid DNA distribution histographic pattern similar to that of acquired pigmented nevi."5.28Use of DAPI cytofluorometric analysis of cellular DNA content to differentiate Spitz nevus from malignant melanoma. ( Chi, HI; Ishibashi, Y; Mihara, I; Otsuka, F; Shima, A, 1990)
" We show a basic approach for using DAPI and phalloidin dyes to detect the early stages of progression and VM of melanoma tumor cells grown in a 3D environment, as well as demonstrating how to acquire images and improve them by changing the software acquisition parameters."4.12Confocal Laser Microscopy for VM Analysis with DAPI and Phalloidin Staining. ( Cesca, K; Oliveira, EM, 2022)
"The cellular DNA ploidy of 30 cases of malignant melanoma was measured by 4',6-diamidino-2-phenylindole-DNA (DAPI-DNA) microfluorometry."3.68Epithelioid cell melanomas have greater DNA ploidy abnormalities than spindle cell melanomas: cytological evidence for a higher malignant potential of the former. ( Chi, HI; Otsuka, F; Umebayashi, Y; Uyeda, Y, 1993)
"Among 20 Spitz nevi examined, 18 of them showed a diploid DNA distribution histographic pattern similar to that of acquired pigmented nevi."1.28Use of DAPI cytofluorometric analysis of cellular DNA content to differentiate Spitz nevus from malignant melanoma. ( Chi, HI; Ishibashi, Y; Mihara, I; Otsuka, F; Shima, A, 1990)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's2 (33.33)18.2507
2000's1 (16.67)29.6817
2010's1 (16.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Cesca, K1
Oliveira, EM1
Tchafa, AM1
Shah, AD1
Wang, S1
Duong, MT1
Shieh, AC1
Chi, HI2
Uyeda, Y1
Umebayashi, Y1
Otsuka, F2
Gruber, BM1
Anuszewska, EL1
Skierski, JS1
Mildner, B1
Chandra, P1
Ishibashi, Y1
Shima, A1
Mihara, I1

Other Studies

6 other studies available for dapi and Melanoma

ArticleYear
Confocal Laser Microscopy for VM Analysis with DAPI and Phalloidin Staining.
    Methods in molecular biology (Clifton, N.J.), 2022, Volume: 2514

    Topics: Humans; Indoles; Melanoma; Microscopy, Confocal; Neovascularization, Pathologic; Phalloidine; Staini

2022
Three-dimensional cell culture model for measuring the effects of interstitial fluid flow on tumor cell invasion.
    Journal of visualized experiments : JoVE, 2012, Jul-25, Issue:65

    Topics: Cell Culture Techniques; Cell Line, Tumor; Cell Movement; Extracellular Fluid; Fluorescent Dyes; Hum

2012
Epithelioid cell melanomas have greater DNA ploidy abnormalities than spindle cell melanomas: cytological evidence for a higher malignant potential of the former.
    Archives of dermatological research, 1993, Volume: 285, Issue:7

    Topics: Adult; Aged; Cytophotometry; DNA, Neoplasm; Female; Fluorescent Dyes; Humans; Indoles; Male; Melanom

1993
Activation of programmed cell death (apoptosis) by adriamycin in human neoplastic cells.
    Mutation research, 2001, Dec-12, Volume: 484, Issue:1-2

    Topics: Antineoplastic Agents; Apoptosis; Doxorubicin; Drug Resistance, Neoplasm; Flow Cytometry; Fluorescen

2001
[Molecular mechanism of action of diamidinephenylindole (DAPI). II. Effect of DAPI on the template activity of DNA and polydeoxynucleotides in the DNA-polymerase system from bacteria, eukaryotic cells and RNA tumor viruses (author's transl)].
    Cellular and molecular biology, including cyto-enzymology, 1979, Volume: 25, Issue:6

    Topics: Amidines; Base Composition; DNA; DNA Replication; Escherichia coli; Friend murine leukemia virus; Hu

1979
Use of DAPI cytofluorometric analysis of cellular DNA content to differentiate Spitz nevus from malignant melanoma.
    The Journal of investigative dermatology, 1990, Volume: 95, Issue:2

    Topics: Adult; Diagnosis, Differential; DNA, Neoplasm; Flow Cytometry; Fluorescent Dyes; Humans; Indoles; Me

1990