Page last updated: 2024-10-25

dapi and Leukemia

dapi has been researched along with Leukemia in 7 studies

DAPI: RN given refers to parent cpd.

Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)

Research Excerpts

ExcerptRelevanceReference
" Based on the fact that an increasing number of adenosine analogues show their antiproliferative and cytotoxic activity via induction of apoptosis, we assessed the effect of cordycepin, a polyadenylation specific inhibitor, an adenosine analogue and a well-known chemotherapeutic drug, on two human leukemia and lymphoma cell lines."7.74The effect of the polyadenylation inhibitor cordycepin on human Molt-4 and Daudi leukaemia and lymphoma cell lines. ( Scorilas, A; Thomadaki, H; Tsiapalis, CM, 2008)
"For this purpose, a variety of leukemia and lymphoma cell lines (U937, K562, HL-60, Daudi, Molt-4) were treated with the anticancer drugs etoposide and/or cordycepin and assessed for poly(A) polymerase (PAP) activity and isoforms by the highly sensitive PAP activity assay and western blotting, respectively."3.74The role of cordycepin in cancer treatment via induction or inhibition of apoptosis: implication of polyadenylation in a cell type specific manner. ( Havredaki, M; Scorilas, A; Thomadaki, H; Tsiapalis, CM, 2008)
" Based on the fact that an increasing number of adenosine analogues show their antiproliferative and cytotoxic activity via induction of apoptosis, we assessed the effect of cordycepin, a polyadenylation specific inhibitor, an adenosine analogue and a well-known chemotherapeutic drug, on two human leukemia and lymphoma cell lines."3.74The effect of the polyadenylation inhibitor cordycepin on human Molt-4 and Daudi leukaemia and lymphoma cell lines. ( Scorilas, A; Thomadaki, H; Tsiapalis, CM, 2008)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's1 (14.29)18.2507
2000's4 (57.14)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Park, JH1
Jin, CY1
Lee, BK1
Kim, GY1
Choi, YH1
Jeong, YK1
Dahlawi, H1
Jordan-Mahy, N1
Clench, MR1
Le Maitre, CL1
Thomadaki, H2
Scorilas, A2
Tsiapalis, CM2
Havredaki, M1
Caravatta, L1
Sancilio, S1
di Giacomo, V1
Rana, R1
Cataldi, A1
Di Pietro, R1
Uphoff, CC1
Gignac, SM1
Drexler, HG1
Park, CH1
Kimler, BF1
Smith, TK1

Other Studies

7 other studies available for dapi and Leukemia

ArticleYear
Naringenin induces apoptosis through downregulation of Akt and caspase-3 activation in human leukemia THP-1 cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2008, Volume: 46, Issue:12

    Topics: Apoptosis; Caspase 3; Cell Line, Tumor; Cell Survival; Cells, Cultured; Down-Regulation; Electrophor

2008
Bioactive actions of pomegranate fruit extracts on leukemia cell lines in vitro hold promise for new therapeutic agents for leukemia.
    Nutrition and cancer, 2012, Volume: 64, Issue:1

    Topics: Annexins; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Death; Drug Screening Assay

2012
The role of cordycepin in cancer treatment via induction or inhibition of apoptosis: implication of polyadenylation in a cell type specific manner.
    Cancer chemotherapy and pharmacology, 2008, Volume: 61, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Caspase 6; C

2008
The effect of the polyadenylation inhibitor cordycepin on human Molt-4 and Daudi leukaemia and lymphoma cell lines.
    Cancer chemotherapy and pharmacology, 2008, Volume: 61, Issue:4

    Topics: Antineoplastic Agents; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Deoxyade

2008
PI3-K/Akt-dependent activation of cAMP-response element-binding (CREB) protein in Jurkat T leukemia cells treated with TRAIL.
    Journal of cellular physiology, 2008, Volume: 214, Issue:1

    Topics: Apoptosis; Caspase 3; Cell Culture Techniques; Chromones; Clone Cells; Cyclic AMP Response Element-B

2008
Mycoplasma contamination in human leukemia cell lines. I. Comparison of various detection methods.
    Journal of immunological methods, 1992, Apr-27, Volume: 149, Issue:1

    Topics: Antibodies, Monoclonal; Cell Line; Cells, Cultured; DNA; Enzyme-Linked Immunosorbent Assay; Fluoresc

1992
Comparison of the supravital DNA dyes Hoechst 33342 and DAPI for flow cytometry and clonogenicity studies of human leukemic marrow cells.
    Experimental hematology, 1985, Volume: 13, Issue:10

    Topics: Acute Disease; Animals; Benzimidazoles; Bone Marrow; Breast Neoplasms; Cell Line; Cell Survival; Clo

1985