dapi and Leukemia
dapi has been researched along with Leukemia in 7 studies
DAPI: RN given refers to parent cpd.
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " Based on the fact that an increasing number of adenosine analogues show their antiproliferative and cytotoxic activity via induction of apoptosis, we assessed the effect of cordycepin, a polyadenylation specific inhibitor, an adenosine analogue and a well-known chemotherapeutic drug, on two human leukemia and lymphoma cell lines." | 7.74 | The effect of the polyadenylation inhibitor cordycepin on human Molt-4 and Daudi leukaemia and lymphoma cell lines. ( Scorilas, A; Thomadaki, H; Tsiapalis, CM, 2008) |
| "For this purpose, a variety of leukemia and lymphoma cell lines (U937, K562, HL-60, Daudi, Molt-4) were treated with the anticancer drugs etoposide and/or cordycepin and assessed for poly(A) polymerase (PAP) activity and isoforms by the highly sensitive PAP activity assay and western blotting, respectively." | 3.74 | The role of cordycepin in cancer treatment via induction or inhibition of apoptosis: implication of polyadenylation in a cell type specific manner. ( Havredaki, M; Scorilas, A; Thomadaki, H; Tsiapalis, CM, 2008) |
| " Based on the fact that an increasing number of adenosine analogues show their antiproliferative and cytotoxic activity via induction of apoptosis, we assessed the effect of cordycepin, a polyadenylation specific inhibitor, an adenosine analogue and a well-known chemotherapeutic drug, on two human leukemia and lymphoma cell lines." | 3.74 | The effect of the polyadenylation inhibitor cordycepin on human Molt-4 and Daudi leukaemia and lymphoma cell lines. ( Scorilas, A; Thomadaki, H; Tsiapalis, CM, 2008) |
Research
Studies (7)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Park, JH | 1 |
| Jin, CY | 1 |
| Lee, BK | 1 |
| Kim, GY | 1 |
| Choi, YH | 1 |
| Jeong, YK | 1 |
| Dahlawi, H | 1 |
| Jordan-Mahy, N | 1 |
| Clench, MR | 1 |
| Le Maitre, CL | 1 |
| Thomadaki, H | 2 |
| Scorilas, A | 2 |
| Tsiapalis, CM | 2 |
| Havredaki, M | 1 |
| Caravatta, L | 1 |
| Sancilio, S | 1 |
| di Giacomo, V | 1 |
| Rana, R | 1 |
| Cataldi, A | 1 |
| Di Pietro, R | 1 |
| Uphoff, CC | 1 |
| Gignac, SM | 1 |
| Drexler, HG | 1 |
| Park, CH | 1 |
| Kimler, BF | 1 |
| Smith, TK | 1 |
Other Studies
7 other studies available for dapi and Leukemia
| Article | Year |
|---|---|
Naringenin induces apoptosis through downregulation of Akt and caspase-3 activation in human leukemia THP-1 cells.
Topics: Apoptosis; Caspase 3; Cell Line, Tumor; Cell Survival; Cells, Cultured; Down-Regulation; Electrophor | 2008 |
Bioactive actions of pomegranate fruit extracts on leukemia cell lines in vitro hold promise for new therapeutic agents for leukemia.
Topics: Annexins; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Death; Drug Screening Assay | 2012 |
The role of cordycepin in cancer treatment via induction or inhibition of apoptosis: implication of polyadenylation in a cell type specific manner.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Caspase 6; C | 2008 |
The effect of the polyadenylation inhibitor cordycepin on human Molt-4 and Daudi leukaemia and lymphoma cell lines.
Topics: Antineoplastic Agents; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Deoxyade | 2008 |
PI3-K/Akt-dependent activation of cAMP-response element-binding (CREB) protein in Jurkat T leukemia cells treated with TRAIL.
Topics: Apoptosis; Caspase 3; Cell Culture Techniques; Chromones; Clone Cells; Cyclic AMP Response Element-B | 2008 |
Mycoplasma contamination in human leukemia cell lines. I. Comparison of various detection methods.
Topics: Antibodies, Monoclonal; Cell Line; Cells, Cultured; DNA; Enzyme-Linked Immunosorbent Assay; Fluoresc | 1992 |
Comparison of the supravital DNA dyes Hoechst 33342 and DAPI for flow cytometry and clonogenicity studies of human leukemic marrow cells.
Topics: Acute Disease; Animals; Benzimidazoles; Bone Marrow; Breast Neoplasms; Cell Line; Cell Survival; Clo | 1985 |