dapi has been researched along with Disease Models, Animal in 125 studies
DAPI: RN given refers to parent cpd.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Bioavailability study indicated a rapid increase in curcumin in plasma and brain within 1 hr after treatment." | 5.33 | Neuroprotective mechanisms of curcumin against cerebral ischemia-induced neuronal apoptosis and behavioral deficits. ( Jensen, MD; Lubahn, DE; MacDonald, RS; Miller, DK; Rottinghaus, GE; Shelat, PB; Simonyi, A; Sun, AY; Sun, GY; Wang, Q; Weisman, GA, 2005) |
| "The majority of neuritic plaques are decorated by IgG." | 2.74 | Autoantibodies against beta-amyloid are common in Alzheimer's disease and help control plaque burden. ( Bernreuther, C; Ferrer, I; Glatzel, M; Kellner, A; Matschke, J; Moch, H, 2009) |
| "Taurine levels were 67% lower in vigabatrin-treated animals than in control animals." | 2.74 | Taurine deficiency is a cause of vigabatrin-induced retinal phototoxicity. ( Chiron, C; Collins, SD; Coriat, C; Craft, CM; Duboc, A; Dubus, E; Dulac, O; Jammoul, F; Nabbout, R; Picaud, S; Sahel, JA; Simonutti, M; Wang, Q; Ye, W, 2009) |
| "The DAPI structure has been modified by replacing the phenyl group with substituted phenyl or heteroaryl rings." | 1.46 | Exploration of DAPI analogues: Synthesis, antitrypanosomal activity, DNA binding and fluorescence properties. ( Boykin, DW; Brun, R; Farahat, AA; Kumar, A; Paul, A; Say, M; Wenzler, T; Wilson, WD, 2017) |
| "A brief 3-min middle cerebral artery occlusion (MCAO) was employed to induce IPC in male mice 72 h before 90-min MCAO." | 1.38 | Preconditioning induces sustained neuroprotection by downregulation of adenosine 5'-monophosphate-activated protein kinase. ( Benashski, SE; Li, J; McCullough, LD; Tarabishy, S; Venna, VR, 2012) |
| "Neurogenic pulmonary edema (NPE) is a well-known complication of subarachnoid hemorrhage (SAH), which potentially causes a poor outcome." | 1.37 | Subarachnoid hemorrhage causes pulmonary endothelial cell apoptosis and neurogenic pulmonary edema in mice. ( Chen, W; Hasegawa, Y; Kanamaru, K; Sozen, T; Suzuki, H; Taki, W; Zhang, JH, 2011) |
| "Severe murine experimental autoimmune neuritis (sm-EAN) in SJL/J mice is a recently described, but incompletely characterized mouse model of Guillain-Barré syndrome (GBS)." | 1.36 | Clinical, electrophysiological and pathologic correlations in a severe murine experimental autoimmune neuritis model of Guillain-Barré syndrome. ( Ubogu, EE; Xia, RH; Yosef, N, 2010) |
| "Inflammatory cascades induced by spinal cord injuries (SCI) are localized in the white matter, a recognized neural stem- and progenitor-cell (NSPC) niche of the adult spinal cord." | 1.36 | Chemokine expression in the white matter spinal cord precursor niche after force-defined spinal cord contusion injuries in adult rats. ( Held-Feindt, J; Knerlich-Lukoschus, F; Lucius, R; Mehdorn, HM; von der Ropp-Brenner, B, 2010) |
| "During acute demyelination, microglial/macrophage activation was most extensive and axons exhibited swellings, neurofilament dephosphorylation, and reduced diameters." | 1.36 | Rostrocaudal analysis of corpus callosum demyelination and axon damage across disease stages refines diffusion tensor imaging correlations with pathological features. ( Armstrong, RC; Budde, MD; Chen, CI; Cross, AH; McDaniel, DP; Song, SK; Tobin, JE; Trinkaus, K; Xie, M, 2010) |
| "The neuropathological hallmarks of Alzheimer's disease (AD) include the presence of extracellular amyloid-beta peptide (Abeta) in the form of amyloid plaques in the brain parenchyma and neuronal loss." | 1.36 | The therapeutic potential of human umbilical cord blood-derived mesenchymal stem cells in Alzheimer's disease. ( Bae, JS; Carter, JE; Jin, HK; Lee, H; Lee, HJ; Lee, JK; Sakamoto, T; Shin, JW, 2010) |
| "Spinocerebellar ataxia type 1 (SCA1) is one of several progressive neurodegenerative diseases caused by the expanded polyglutamine tract in ataxin-1, the SCA1 gene product." | 1.36 | SUMO-1 interacts with mutant ataxin-1 and colocalizes to its aggregates in Purkinje cells of SCA1 transgenic mice. ( Hong, S; Kang, S, 2010) |
| "Globoid cell leukodystrophy (GLD; Krabbe's disease), caused by a genetic galactosylceramidase deficiency, affects both the central and peripheral nervous systems (CNS and PNS)." | 1.35 | Peripheral neuropathy in the twitcher mouse: accumulation of extracellular matrix in the endoneurium and aberrant expression of ion channels. ( Kagitani-Shimono, K; Mohri, I; Suzuki, K; Taniike, M; Yagi, T, 2008) |
| "Chronic hydrocephalus (CH) is a neurological disease characterized by increased cerebrospinal fluid volume and pressure that is often associated with impaired cognitive function." | 1.35 | Chronic hydrocephalus-induced hypoxia: increased expression of VEGFR-2+ and blood vessel density in hippocampus. ( Deshpande, A; Dingwall, C; Dombrowski, SM; Leibson, Z; Leichliter, A; Luciano, MG, 2008) |
| "Ibuprofen-treated transgenic mice showed a significant decrease in intraneuronal oligomeric Abeta and hyperphosphorylated tau (AT8) immunoreactivity in the hippocampus." | 1.35 | Ibuprofen reduces Abeta, hyperphosphorylated tau and memory deficits in Alzheimer mice. ( Carreras, I; Dedeoglu, A; Hossain, L; Jenkins, BG; Klein, WL; Kowall, NW; LaFerla, FM; McKee, AC; Oddo, S; Ryu, H, 2008) |
| "We report for the first time that in Japanese Encephalitis, microglia and astrocytes both produce IL-18 and IL-1beta." | 1.35 | Japanese Encephalitis Virus infection induces IL-18 and IL-1beta in microglia and astrocytes: correlation with in vitro cytokine responsiveness of glial cells and subsequent neuronal death. ( Basu, A; Das, S; Ghosh, J; Mishra, MK, 2008) |
| "These findings suggest that seizure activity in SS gerbils may be related to the selective hyperactivation of interneurons in stratum lacunosum-moleculare via the up-regulation of VGSC II expression, which leads to the disinhibition of CA1 pyramidal cells." | 1.35 | Voltage-gated Na+ channel II immunoreactivity is selectively up-regulated in hippocampal interneurons of seizure sensitive gerbils. ( Choi, HC; Jo, SM; Kang, TC; Kim, JE; Kim, YI; Kwak, SE; Song, HK, 2008) |
| " Bioavailability study indicated a rapid increase in curcumin in plasma and brain within 1 hr after treatment." | 1.33 | Neuroprotective mechanisms of curcumin against cerebral ischemia-induced neuronal apoptosis and behavioral deficits. ( Jensen, MD; Lubahn, DE; MacDonald, RS; Miller, DK; Rottinghaus, GE; Shelat, PB; Simonyi, A; Sun, AY; Sun, GY; Wang, Q; Weisman, GA, 2005) |
| "Heart failure was induced in rabbit by intravenous administration of doxorubicin." | 1.33 | Cell transplantation with a catheter-based approach: an efficient method for the treatment of heart failure with multiple lesions. ( Chen, M; Deng, JL; Fan, ZC; Huang, DJ; Liu, XJ; Yang, Q, 2006) |
| "Here we show that after a transient cerebral ischemia, hyperphosphorylated tau accumulates in cortical neurons in a site-specific manner." | 1.32 | Transient cerebral ischemia induces site-specific hyperphosphorylation of tau protein. ( Liu, R; Simpkins, JW; Wen, Y; Yang, S, 2004) |
| "Carbon tetrachloride (CCl4) was fed by gavage to rats, and 2, 7, 14, and 28 days later, small and large cholangiocytes were isolated." | 1.30 | Acute carbon tetrachloride feeding selectively damages large, but not small, cholangiocytes from normal rat liver. ( Alpini, G; Baiocchi, L; Benedetti, A; Caligiuri, A; Francis, H; Glaser, S; Lasater, J; LeSage, GD; Marucci, L; Phinizy, JL; Rodgers, R; Tretjak, Z; Ugili, L, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (0.80) | 18.2507 |
| 2000's | 76 (60.80) | 29.6817 |
| 2010's | 48 (38.40) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bakunov, SA | 1 |
| Bakunova, SM | 1 |
| Wenzler, T | 2 |
| Barszcz, T | 1 |
| Werbovetz, KA | 1 |
| Brun, R | 2 |
| Tidwell, RR | 1 |
| Farahat, AA | 1 |
| Kumar, A | 1 |
| Say, M | 1 |
| Paul, A | 1 |
| Wilson, WD | 1 |
| Boykin, DW | 1 |
| Orita, S | 1 |
| Henry, K | 1 |
| Mantuano, E | 1 |
| Yamauchi, K | 1 |
| De Corato, A | 1 |
| Ishikawa, T | 1 |
| Feltri, ML | 2 |
| Wrabetz, L | 2 |
| Gaultier, A | 1 |
| Pollack, M | 1 |
| Ellisman, M | 1 |
| Takahashi, K | 1 |
| Gonias, SL | 1 |
| Campana, WM | 1 |
| Corrales, A | 1 |
| Vidal, R | 1 |
| García, S | 1 |
| Vidal, V | 1 |
| Martínez, P | 1 |
| García, E | 1 |
| Flórez, J | 1 |
| Sanchez-Barceló, EJ | 1 |
| Martínez-Cué, C | 1 |
| Rueda, N | 1 |
| Wendel, JS | 1 |
| Ye, L | 1 |
| Zhang, P | 1 |
| Tranquillo, RT | 1 |
| Zhang, JJ | 1 |
| Woeffler-Maucler, C | 1 |
| Beghin, A | 1 |
| Ressnikoff, D | 1 |
| Bezin, L | 1 |
| Marinesco, S | 1 |
| Wang, Y | 2 |
| Qu, L | 1 |
| Wang, XL | 1 |
| Gao, L | 1 |
| Li, ZZ | 1 |
| Gao, GD | 1 |
| Yang, Q | 2 |
| Angelova, PR | 1 |
| Agrawalla, BK | 1 |
| Elustondo, PA | 1 |
| Gordon, J | 1 |
| Shiba, T | 1 |
| Abramov, AY | 1 |
| Chang, YT | 1 |
| Pavlov, EV | 1 |
| Pisa, D | 1 |
| Alonso, R | 1 |
| Juarranz, A | 1 |
| Rábano, A | 1 |
| Carrasco, L | 1 |
| Zhu, F | 1 |
| Wang, XQ | 1 |
| Chen, YN | 1 |
| Yang, N | 1 |
| Lang, SY | 1 |
| Zuo, PP | 1 |
| Zhang, JT | 1 |
| Li, RS | 1 |
| Sadallah, M | 1 |
| Labat-Gest, V | 1 |
| Tempia, F | 1 |
| Oglesby, EN | 1 |
| Tezel, G | 1 |
| Cone-Kimball, E | 1 |
| Steinhart, MR | 1 |
| Jefferys, J | 1 |
| Pease, ME | 1 |
| Quigley, HA | 1 |
| Mazzone, GL | 1 |
| Veeraraghavan, P | 1 |
| Gonzalez-Inchauspe, C | 1 |
| Nistri, A | 1 |
| Uchitel, OD | 1 |
| Hanstein, R | 2 |
| Lu, A | 1 |
| Wurst, W | 1 |
| Holsboer, F | 1 |
| Deussing, JM | 1 |
| Clement, AB | 2 |
| Behl, C | 2 |
| Mattis, VB | 1 |
| Butchbach, ME | 1 |
| Lorson, CL | 1 |
| Kuramoto, S | 1 |
| Yasuhara, T | 1 |
| Agari, T | 1 |
| Kondo, A | 1 |
| Matsui, T | 1 |
| Miyoshi, Y | 1 |
| Shingo, T | 1 |
| Date, I | 1 |
| Engel, T | 1 |
| Goñi-Oliver, P | 1 |
| Gomez-Ramos, P | 1 |
| Morán, MA | 1 |
| Lucas, JJ | 1 |
| Avila, J | 1 |
| Hernández, F | 1 |
| Li, L | 1 |
| Rasul, I | 1 |
| Liu, J | 1 |
| Zhao, B | 2 |
| Tang, R | 1 |
| Premont, RT | 1 |
| Suo, WZ | 1 |
| Marques, SA | 2 |
| Garcez, VF | 1 |
| Del Bel, EA | 1 |
| Martinez, AM | 3 |
| Xuan, AG | 1 |
| Luo, M | 1 |
| Ji, WD | 1 |
| Long, DH | 1 |
| Keiner, S | 1 |
| Witte, OW | 1 |
| Redecker, C | 1 |
| Carter, LM | 1 |
| Starkey, ML | 1 |
| Akrimi, SF | 1 |
| Davies, M | 1 |
| McMahon, SB | 1 |
| Bradbury, EJ | 1 |
| Milanski, M | 1 |
| Degasperi, G | 1 |
| Coope, A | 1 |
| Morari, J | 1 |
| Denis, R | 1 |
| Cintra, DE | 1 |
| Tsukumo, DM | 1 |
| Anhe, G | 1 |
| Amaral, ME | 1 |
| Takahashi, HK | 1 |
| Curi, R | 1 |
| Oliveira, HC | 1 |
| Carvalheira, JB | 1 |
| Bordin, S | 1 |
| Saad, MJ | 1 |
| Velloso, LA | 1 |
| Jeong, SY | 1 |
| Rathore, KI | 1 |
| Schulz, K | 1 |
| Ponka, P | 1 |
| Arosio, P | 1 |
| David, S | 1 |
| Kellner, A | 1 |
| Matschke, J | 1 |
| Bernreuther, C | 1 |
| Moch, H | 1 |
| Ferrer, I | 1 |
| Glatzel, M | 1 |
| Jammoul, F | 1 |
| Wang, Q | 2 |
| Nabbout, R | 1 |
| Coriat, C | 1 |
| Duboc, A | 1 |
| Simonutti, M | 1 |
| Dubus, E | 1 |
| Craft, CM | 1 |
| Ye, W | 1 |
| Collins, SD | 1 |
| Dulac, O | 1 |
| Chiron, C | 1 |
| Sahel, JA | 1 |
| Picaud, S | 1 |
| Li, T | 1 |
| Ren, G | 1 |
| Kaplan, DL | 1 |
| Boison, D | 1 |
| Kim, JE | 2 |
| Kwak, SE | 2 |
| Kang, TC | 2 |
| Narciso, MS | 1 |
| Mietto, Bde S | 1 |
| Soares, CP | 1 |
| Mermelstein, Cdos S | 1 |
| El-Cheikh, MC | 1 |
| Smith, D | 1 |
| Tweed, C | 1 |
| Fernyhough, P | 2 |
| Glazner, GW | 1 |
| Baptiste, DC | 1 |
| Austin, JW | 1 |
| Zhao, W | 1 |
| Nahirny, A | 1 |
| Sugita, S | 1 |
| Fehlings, MG | 1 |
| Louboutin, JP | 2 |
| Agrawal, L | 2 |
| Reyes, BA | 2 |
| Van Bockstaele, EJ | 2 |
| Strayer, DS | 2 |
| Akude, E | 1 |
| Zherebitskaya, E | 1 |
| Roy Chowdhury, SK | 1 |
| Girling, K | 1 |
| Jackson, J | 1 |
| Chapon, C | 1 |
| Jones, W | 1 |
| Hirani, E | 1 |
| Qassim, A | 1 |
| Bhakoo, K | 1 |
| Gao, X | 1 |
| Enikolopov, G | 1 |
| Chen, J | 2 |
| Garrett, FG | 1 |
| Durham, PL | 1 |
| Wallenquist, U | 1 |
| Brännvall, K | 1 |
| Clausen, F | 1 |
| Lewén, A | 1 |
| Hillered, L | 1 |
| Forsberg-Nilsson, K | 1 |
| Spanswick, SC | 1 |
| Bray, D | 1 |
| Zelinski, EL | 1 |
| Sutherland, RJ | 1 |
| Nakka, VP | 1 |
| Gusain, A | 1 |
| Raghubir, R | 1 |
| Cool, BH | 1 |
| Zitnik, G | 1 |
| Martin, GM | 1 |
| Hu, Q | 1 |
| Strecker, JK | 2 |
| Sevimli, S | 1 |
| Schilling, M | 2 |
| Klocke, R | 1 |
| Nikol, S | 1 |
| Schneider, A | 1 |
| Schäbitz, WR | 1 |
| Xia, RH | 1 |
| Yosef, N | 1 |
| Ubogu, EE | 1 |
| Knerlich-Lukoschus, F | 1 |
| von der Ropp-Brenner, B | 1 |
| Lucius, R | 1 |
| Mehdorn, HM | 1 |
| Held-Feindt, J | 1 |
| Gerard, M | 1 |
| Deleersnijder, A | 1 |
| Daniëls, V | 1 |
| Schreurs, S | 1 |
| Munck, S | 1 |
| Reumers, V | 1 |
| Pottel, H | 1 |
| Engelborghs, Y | 1 |
| Van den Haute, C | 1 |
| Taymans, JM | 1 |
| Debyser, Z | 1 |
| Baekelandt, V | 1 |
| Morisaki, S | 1 |
| Nishi, M | 1 |
| Fujiwara, H | 1 |
| Oda, R | 1 |
| Kawata, M | 1 |
| Kubo, T | 1 |
| Prajapati, KD | 1 |
| Sharma, SS | 1 |
| Roy, N | 1 |
| Yun, B | 1 |
| Anderegg, A | 1 |
| Menichella, D | 1 |
| Awatramani, R | 1 |
| Ritson, GP | 1 |
| Custer, SK | 1 |
| Freibaum, BD | 1 |
| Guinto, JB | 1 |
| Geffel, D | 1 |
| Moore, J | 1 |
| Tang, W | 1 |
| Winton, MJ | 1 |
| Neumann, M | 1 |
| Trojanowski, JQ | 2 |
| Lee, VM | 2 |
| Forman, MS | 1 |
| Taylor, JP | 1 |
| Xie, M | 1 |
| Tobin, JE | 1 |
| Budde, MD | 1 |
| Chen, CI | 1 |
| Trinkaus, K | 1 |
| Cross, AH | 1 |
| McDaniel, DP | 1 |
| Song, SK | 1 |
| Armstrong, RC | 1 |
| Lee, HJ | 1 |
| Lee, JK | 1 |
| Lee, H | 1 |
| Shin, JW | 1 |
| Carter, JE | 1 |
| Sakamoto, T | 1 |
| Jin, HK | 1 |
| Bae, JS | 1 |
| Nichterwitz, S | 1 |
| Hoffmann, N | 1 |
| Hajosch, R | 1 |
| Oberhoffner, S | 1 |
| Schlosshauer, B | 1 |
| Snyder-Keller, A | 1 |
| McLear, JA | 1 |
| Hathorn, T | 1 |
| Messer, A | 1 |
| Nout, YS | 1 |
| Culp, E | 1 |
| Schmidt, MH | 1 |
| Tovar, CA | 1 |
| Pröschel, C | 1 |
| Mayer-Pröschel, M | 1 |
| Noble, MD | 1 |
| Beattie, MS | 1 |
| Bresnahan, JC | 1 |
| Bozkurt, G | 1 |
| Mothe, AJ | 1 |
| Zahir, T | 1 |
| Kim, H | 1 |
| Shoichet, MS | 1 |
| Tator, CH | 1 |
| Lee, J | 1 |
| Kosaras, B | 1 |
| Del Signore, SJ | 1 |
| Cormier, K | 1 |
| McKee, A | 1 |
| Ratan, RR | 1 |
| Kowall, NW | 2 |
| Ryu, H | 2 |
| Hu, X | 1 |
| Weng, Z | 1 |
| Chu, CT | 1 |
| Zhang, L | 1 |
| Cao, G | 1 |
| Gao, Y | 1 |
| Signore, A | 1 |
| Zhu, J | 1 |
| Hastings, T | 1 |
| Greenamyre, JT | 1 |
| Kang, S | 1 |
| Hong, S | 1 |
| Pérez-González, R | 1 |
| Antequera, D | 1 |
| Vargas, T | 1 |
| Spuch, C | 1 |
| Bolós, M | 1 |
| Carro, E | 1 |
| Rose, K | 1 |
| Ooi, L | 1 |
| Dalle, C | 1 |
| Robertson, B | 1 |
| Wood, IC | 1 |
| Gamper, N | 1 |
| Yu, YM | 1 |
| Cristofanilli, M | 1 |
| Valiveti, A | 1 |
| Ma, L | 1 |
| Yoo, M | 1 |
| Morellini, F | 1 |
| Schachner, M | 1 |
| Jiang, Y | 1 |
| Lv, H | 1 |
| Huang, S | 1 |
| Tan, H | 1 |
| Zhang, Y | 2 |
| Li, H | 1 |
| Jarosik, J | 1 |
| Legutko, B | 1 |
| Werner, S | 1 |
| Unsicker, K | 1 |
| von Bohlen Und Halbach, O | 1 |
| Volz, F | 1 |
| Bock, HH | 1 |
| Gierthmuehlen, M | 1 |
| Zentner, J | 1 |
| Haas, CA | 1 |
| Freiman, TM | 1 |
| Fox, LM | 1 |
| William, CM | 1 |
| Adamowicz, DH | 1 |
| Pitstick, R | 1 |
| Carlson, GA | 1 |
| Spires-Jones, TL | 1 |
| Hyman, BT | 1 |
| Suzuki, H | 1 |
| Sozen, T | 1 |
| Hasegawa, Y | 1 |
| Chen, W | 1 |
| Kanamaru, K | 1 |
| Taki, W | 1 |
| Zhang, JH | 1 |
| Lim, Y | 1 |
| Kehm, VM | 1 |
| Lee, EB | 1 |
| Soper, JH | 1 |
| Li, C | 1 |
| Venna, VR | 1 |
| Li, J | 2 |
| Benashski, SE | 1 |
| Tarabishy, S | 1 |
| McCullough, LD | 1 |
| Tang, HL | 1 |
| Wang, ZG | 1 |
| Li, Q | 1 |
| Ran, HT | 1 |
| Zheng, YY | 1 |
| Ren, JL | 1 |
| Ling, ZY | 1 |
| Li, A | 1 |
| Wang, GX | 1 |
| Zhan, YA | 1 |
| Hu, HL | 1 |
| Fu, B | 1 |
| Li, GC | 1 |
| Ye, QH | 1 |
| Dong, QZ | 1 |
| Ren, N | 1 |
| Jia, HL | 1 |
| Qin, LX | 1 |
| Woo, MS | 1 |
| Wang, X | 2 |
| Faustino, JV | 1 |
| Derugin, N | 1 |
| Wendland, MF | 1 |
| Zhou, P | 1 |
| Iadecola, C | 1 |
| Vexler, ZS | 1 |
| Hong, SH | 1 |
| Piao, S | 1 |
| Kim, IG | 1 |
| Lee, JY | 2 |
| Cho, HJ | 1 |
| Kim, SW | 1 |
| Hwang, TK | 1 |
| Day, CS | 1 |
| Buranapanitkit, B | 1 |
| Riano, FA | 1 |
| Tomaino, MM | 1 |
| Somogyi, G | 1 |
| Sotereanos, DG | 1 |
| Kuroda, R | 1 |
| Huard, J | 1 |
| Chedrawy, EG | 1 |
| Wang, JS | 1 |
| Nguyen, DM | 1 |
| Shum-Tim, D | 1 |
| Chiu, RC | 1 |
| Jones, BW | 1 |
| Watt, CB | 1 |
| Frederick, JM | 1 |
| Baehr, W | 1 |
| Chen, CK | 1 |
| Levine, EM | 1 |
| Milam, AH | 1 |
| Lavail, MM | 1 |
| Marc, RE | 1 |
| Brundin, L | 1 |
| Brismar, H | 1 |
| Danilov, AI | 1 |
| Olsson, T | 1 |
| Johansson, CB | 1 |
| Karimi, M | 1 |
| Wang, LX | 1 |
| Hammel, JM | 1 |
| Mascio, CE | 1 |
| Abdulhamid, M | 1 |
| Barner, EW | 1 |
| Scholz, TD | 1 |
| Segar, JL | 1 |
| Li, WG | 1 |
| Niles, SD | 1 |
| Caldarone, CA | 1 |
| Nonaka, M | 1 |
| Yoshikawa, M | 1 |
| Nishimura, F | 1 |
| Yokota, H | 1 |
| Kimura, H | 1 |
| Hirabayashi, H | 1 |
| Nakase, H | 1 |
| Ishizaka, S | 1 |
| Wanaka, A | 1 |
| Sakaki, T | 1 |
| Arthur, PG | 1 |
| Lim, SC | 1 |
| Meloni, BP | 1 |
| Munns, SE | 1 |
| Chan, A | 1 |
| Knuckey, NW | 1 |
| Briguet, A | 1 |
| Courdier-Fruh, I | 1 |
| Foster, M | 1 |
| Meier, T | 1 |
| Magyar, JP | 1 |
| Wen, Y | 1 |
| Yang, S | 1 |
| Liu, R | 1 |
| Simpkins, JW | 2 |
| Bajenaru, ML | 1 |
| Garbow, JR | 1 |
| Perry, A | 1 |
| Hernandez, MR | 2 |
| Gutmann, DH | 1 |
| Richardson, RM | 1 |
| Broaddus, WC | 1 |
| Holloway, KL | 1 |
| Fillmore, HL | 1 |
| Skundric, DS | 1 |
| Dai, R | 1 |
| Zakarian, VL | 1 |
| Bessert, D | 1 |
| Skoff, RP | 1 |
| Cruikshank, WW | 1 |
| Kurjakovic, Z | 1 |
| Schmitt, WB | 1 |
| Sprengel, R | 1 |
| Mack, V | 1 |
| Draft, RW | 1 |
| Seeburg, PH | 1 |
| Deacon, RM | 1 |
| Rawlins, JN | 1 |
| Bannerman, DM | 1 |
| Feuer, R | 1 |
| Pagarigan, RR | 1 |
| Harkins, S | 1 |
| Liu, F | 1 |
| Hunziker, IP | 1 |
| Whitton, JL | 1 |
| Prinz, RA | 1 |
| Nakamura-Pereira, M | 1 |
| De-Ary-Pires, B | 1 |
| Fernandes, D | 1 |
| Fabião-Gomes, BD | 1 |
| de Ary-Pires, R | 1 |
| Pires-Neto, MA | 1 |
| Tremblay, ME | 1 |
| Saint-Pierre, M | 1 |
| Bourhis, E | 1 |
| Lévesque, D | 1 |
| Rouillard, C | 1 |
| Cicchetti, F | 1 |
| Tang, YL | 1 |
| Ngomba, RT | 1 |
| Biagioni, F | 1 |
| Casciato, S | 1 |
| Willems-van Bree, E | 1 |
| Battaglia, G | 1 |
| Bruno, V | 1 |
| Nicoletti, F | 1 |
| van Luijtelaar, EL | 1 |
| Sun, AY | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase I, Trial to Evaluate the Safety, Tolerability, and Potential Efficacy of Allogeneic Human Mesenchymal Stem Cell (hMSC) Infusion in Patients With Non-Cystic Fibrosis Bronchiectasis[NCT02625246] | Phase 1 | 6 participants (Actual) | Interventional | 2016-02-04 | Completed | ||
| A Phase I, Trial to Evaluate the Safety, Tolerability, and Potential Efficacy of Allogeneic Human Mesenchymal Stem Cell Infusion in Patients With Mild Asthma[NCT03137199] | Phase 1 | 3 participants (Actual) | Interventional | 2017-06-22 | Terminated (stopped due to First cohort completed. Per sponsor decision.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for dapi and Disease Models, Animal
| Article | Year |
|---|---|
Autologous mesenchymal stem cells for post-ischemic myocardial repair.
Topics: Animals; Bone Marrow Cells; Cells, Cultured; Disease Models, Animal; Fluorescent Antibody Technique, | 2005 |
3 trials available for dapi and Disease Models, Animal
| Article | Year |
|---|---|
Autoantibodies against beta-amyloid are common in Alzheimer's disease and help control plaque burden.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antigens, CD; Antigens, | 2009 |
Taurine deficiency is a cause of vigabatrin-induced retinal phototoxicity.
Topics: Amino Acids; Analysis of Variance; Animals; Child, Preschool; Disease Models, Animal; Dose-Response | 2009 |
Effects of G-CSF treatment on neutrophil mobilization and neurological outcome after transient focal ischemia.
Topics: Animals; Antibodies; Behavior, Animal; Brain Infarction; Cell Movement; Disease Models, Animal; Fema | 2010 |
121 other studies available for dapi and Disease Models, Animal
| Article | Year |
|---|---|
Synthesis and antiprotozoal activity of cationic 2-phenylbenzofurans.
Topics: Animals; Antiprotozoal Agents; Benzofurans; Cations; Disease Models, Animal; Leishmania; Mice; Molec | 2008 |
Exploration of DAPI analogues: Synthesis, antitrypanosomal activity, DNA binding and fluorescence properties.
Topics: Animals; Circular Dichroism; Disease Models, Animal; DNA; Fluorescence; Indoles; Mice; Molecular Str | 2017 |
Schwann cell LRP1 regulates remak bundle ultrastructure and axonal interactions to prevent neuropathic pain.
Topics: Actins; Analysis of Variance; Animals; Axons; CD11b Antigen; Cytoplasm; Disease Models, Animal; Gene | 2013 |
Chronic melatonin treatment rescues electrophysiological and neuromorphological deficits in a mouse model of Down syndrome.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Down Syndrome; Female; Hippocampus; Indoles; | 2014 |
Functional consequences of a tissue-engineered myocardial patch for cardiac repair in a rat infarct model.
Topics: Animals; Disease Models, Animal; Electrocardiography; Extracellular Matrix; Implants, Experimental; | 2014 |
Automated immunohistochemical method to quantify neuronal density in brain sections: application to neuronal loss after status epilepticus.
Topics: Animals; Antibodies, Monoclonal; Antigens, Nuclear; Automation; Brain; Cell Count; Disease Models, A | 2014 |
Firing pattern modulation through SK channel current increase underlies neuronal survival in an organotypic slice model of Parkinson's disease.
Topics: Action Potentials; Animals; Calcium; Cell Death; Cell Survival; Disease Models, Animal; Dopaminergic | 2015 |
In situ investigation of mammalian inorganic polyphosphate localization using novel selective fluorescent probes JC-D7 and JC-D8.
Topics: Animals; Astrocytes; Benzimidazoles; Brain; Cells, Cultured; Dimethyl Sulfoxide; Disease Models, Ani | 2014 |
Direct visualization of fungal infection in brains from patients with Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Antibodies, Fungal; Brain; Candida glabrata; Disease Models, Animal; Fem | 2015 |
Changes and overlapping distribution in the expression of CB1/OX1-GPCRs in rat hippocampus by kainic acid-induced status epilepticus.
Topics: Animals; Antigens, Nuclear; Cell Membrane; Disease Models, Animal; Disease Progression; Fluorescent | 2015 |
Propagation of Neuronal Damage to Embryonic Grafts Transplanted in the Hippocampus of Murine Models of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid; Animals; Astrocytes; Cell Count; Dendritic Spines; Disease Models, Anima | 2015 |
Scleral fibroblast response to experimental glaucoma in mice.
Topics: Actins; Animals; Cell Proliferation; Chromatography, Liquid; Disease Models, Animal; Eye Proteins; F | 2016 |
ASIC channel inhibition enhances excitotoxic neuronal death in an in vitro model of spinal cord injury.
Topics: Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Animals; Cell Death; Cell Survival; Di | 2017 |
Transgenic overexpression of corticotropin releasing hormone provides partial protection against neurodegeneration in an in vivo model of acute excitotoxic stress.
Topics: Analysis of Variance; Animals; Brain-Derived Neurotrophic Factor; Cell Death; Corticotropin-Releasin | 2008 |
Detection of human survival motor neuron (SMN) protein in mice containing the SMN2 transgene: applicability to preclinical therapy development for spinal muscular atrophy.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Cells, Cultured; Disease | 2008 |
Injection of muscimol, a GABAa agonist into the anterior thalamic nucleus, suppresses hippocampal neurogenesis in amygdala-kindled rats.
Topics: Amygdala; Animals; Anterior Thalamic Nuclei; Bromodeoxyuridine; Cell Count; Cell Differentiation; Ce | 2009 |
Hippocampal neuronal subpopulations are differentially affected in double transgenic mice overexpressing frontotemporal dementia and parkinsonism linked to chromosome 17 tau and glycogen synthase kinase-3beta.
Topics: Age Factors; Animals; Antibodies, Monoclonal; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Ca | 2008 |
Augmented axonal defects and synaptic degenerative changes in female GRK5 deficient mice.
Topics: Alzheimer Disease; Animals; Axons; Blotting, Western; Disease Models, Animal; Female; Fluoroimmunoas | 2009 |
A simple, inexpensive and easily reproducible model of spinal cord injury in mice: morphological and functional assessment.
Topics: Animals; Cell Death; Demyelinating Diseases; Disease Models, Animal; Exploratory Behavior; Female; G | 2009 |
Effects of engrafted neural stem cells in Alzheimer's disease rats.
Topics: Alzheimer Disease; Animals; Bromodeoxyuridine; Cell Differentiation; Disease Models, Animal; Embryo, | 2009 |
Immunocytochemical detection of newly generated neurons in the perilesional area of cortical infarcts after intraventricular application of brain-derived neurotrophic factor.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Brain Infarction; Brain-Derived Ne | 2009 |
The yellow fluorescent protein (YFP-H) mouse reveals neuroprotection as a novel mechanism underlying chondroitinase ABC-mediated repair after spinal cord injury.
Topics: Amidines; Animals; Atrophy; Cell Size; Cell Survival; Cerebral Cortex; Chondroitin ABC Lyase; Diseas | 2008 |
Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity.
Topics: Animals; Antibodies; Body Weight; Cytokines; Disease Models, Animal; Fatty Acids; Gene Expression Re | 2009 |
Dysregulation of iron homeostasis in the CNS contributes to disease progression in a mouse model of amyotrophic lateral sclerosis.
Topics: Age Factors; Aldehydes; Amyotrophic Lateral Sclerosis; Animals; Body Weight; Cation Transport Protei | 2009 |
Human mesenchymal stem cell grafts engineered to release adenosine reduce chronic seizures in a mouse model of CA3-selective epileptogenesis.
Topics: Adenosine; Adenosine Kinase; Analysis of Variance; Animals; Disease Models, Animal; Electroencephalo | 2009 |
Upregulated TWIK-related acid-sensitive K+ channel-2 in neurons and perivascular astrocytes in the hippocampus of experimental temporal lobe epilepsy.
Topics: Animals; Astrocytes; Atropine Derivatives; Cerebral Ventricles; Disease Models, Animal; Epilepsy, Te | 2009 |
Sciatic nerve regeneration is accelerated in galectin-3 knockout mice.
Topics: Animals; Antigens, Differentiation; Axons; beta Catenin; Disease Models, Animal; Galectin 3; Indoles | 2009 |
Nuclear factor-kappaB activation in axons and Schwann cells in experimental sciatic nerve injury and its role in modulating axon regeneration: studies with etanercept.
Topics: Animals; Axons; Axotomy; Disease Models, Animal; Dose-Response Relationship, Drug; Electrophoretic M | 2009 |
Systemic polyethylene glycol promotes neurological recovery and tissue sparing in rats after cervical spinal cord injury.
Topics: Analysis of Variance; Animals; Cervical Vertebrae; Cytoskeletal Proteins; Disease Models, Animal; Do | 2009 |
A rat model of human immunodeficiency virus 1 encephalopathy using envelope glycoprotein gp120 expression delivered by SV40 vectors.
Topics: Adenoviruses, Simian; AIDS Dementia Complex; Aldehydes; Animals; Calcium-Binding Proteins; Cell Deat | 2009 |
4-Hydroxy-2-nonenal induces mitochondrial dysfunction and aberrant axonal outgrowth in adult sensory neurons that mimics features of diabetic neuropathy.
Topics: Aldehydes; Animals; Axons; Cells, Cultured; Cysteine Proteinase Inhibitors; Diabetes Mellitus, Exper | 2010 |
In vivo multimodal imaging of stem cell transplantation in a rodent model of Parkinson's disease.
Topics: Adult Stem Cells; Animals; Antipsychotic Agents; Carbon Isotopes; Diagnostic Imaging; Disease Models | 2009 |
Moderate traumatic brain injury promotes proliferation of quiescent neural progenitors in the adult hippocampus.
Topics: Adult Stem Cells; Animals; Brain Injuries; Bromodeoxyuridine; Cell Proliferation; Dentate Gyrus; Dis | 2009 |
Differential expression of connexins in trigeminal ganglion neurons and satellite glial cells in response to chronic or acute joint inflammation.
Topics: Animals; Capsaicin; Connexins; Disease Models, Animal; Freund's Adjuvant; Gene Expression Regulation | 2008 |
Grafted neural progenitors migrate and form neurons after experimental traumatic brain injury.
Topics: Actins; Animals; Brain Injuries; Cell Count; Cell Movement; Disease Models, Animal; Embryo, Mammalia | 2009 |
A novel method for reliable nuclear antibody detection in tissue with high levels of pathology-induced autofluorescence.
Topics: Animals; Antibodies; Artifacts; Benzimidazoles; Biomarkers; Brain Infarction; Cell Nucleus; Dentate | 2009 |
Endoplasmic reticulum stress plays critical role in brain damage after cerebral ischemia/reperfusion in rats.
Topics: Activating Transcription Factor 4; Animals; Brain; Caspase 12; Cinnamates; Disease Models, Animal; D | 2010 |
Structural and functional characterization of a novel FE65 protein product up-regulated in cognitively impaired FE65 knockout mice.
Topics: Amyloid beta-Protein Precursor; Animals; Cell Line; Chlorocebus aethiops; Cognition Disorders; Disea | 2010 |
HIV-1 gp120-induced neuroinflammation: relationship to neuron loss and protection by rSV40-delivered antioxidant enzymes.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antioxidants; Aquaporins; Calcium- | 2010 |
Clinical, electrophysiological and pathologic correlations in a severe murine experimental autoimmune neuritis model of Guillain-Barré syndrome.
Topics: Action Potentials; Animals; Antigens, CD; Antigens, Differentiation; Cell Proliferation; Disease Mod | 2010 |
Chemokine expression in the white matter spinal cord precursor niche after force-defined spinal cord contusion injuries in adult rats.
Topics: Analysis of Variance; Animals; Bromodeoxyuridine; Cell Proliferation; Chemokines; Disease Models, An | 2010 |
Inhibition of FK506 binding proteins reduces alpha-synuclein aggregation and Parkinson's disease-like pathology.
Topics: Age Factors; alpha-Synuclein; Animals; Apoptosis; Cells, Cultured; Corpus Striatum; Disease Models, | 2010 |
Endogenous glucocorticoids improve myelination via Schwann cells after peripheral nerve injury: An in vivo study using a crush injury model.
Topics: Adrenalectomy; Analysis of Variance; Animals; Corticosterone; Disease Models, Animal; Dose-Response | 2010 |
Upregulation of albumin expression in focal ischemic rat brain.
Topics: Albumins; Analysis of Variance; Animals; Brain Infarction; Disease Models, Animal; Electrophoresis, | 2010 |
MicroRNA-deficient Schwann cells display congenital hypomyelination.
Topics: Animals; Animals, Newborn; Bromodeoxyuridine; Cell Differentiation; Cyclin D1; DEAD-box RNA Helicase | 2010 |
TDP-43 mediates degeneration in a novel Drosophila model of disease caused by mutations in VCP/p97.
Topics: Aminopeptidases; Animals; Animals, Genetically Modified; Binding Sites; Cell Cycle Proteins; Cell Li | 2010 |
Rostrocaudal analysis of corpus callosum demyelination and axon damage across disease stages refines diffusion tensor imaging correlations with pathological features.
Topics: Animals; CD11b Antigen; Corpus Callosum; Cuprizone; Demyelinating Diseases; Diffuse Axonal Injury; D | 2010 |
The therapeutic potential of human umbilical cord blood-derived mesenchymal stem cells in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Animals; Apoptosis; Behavior, Animal | 2010 |
Bioengineered glial strands for nerve regeneration.
Topics: Animals; Biocompatible Materials; Bioengineering; Bromodeoxyuridine; Cell Movement; Cell Proliferati | 2010 |
Early or late-stage anti-N-terminal Huntingtin intrabody gene therapy reduces pathological features in B6.HDR6/1 mice.
Topics: Age Factors; Animals; Antibodies; Disease Models, Animal; Genetic Therapy; Genetic Vectors; Huntingt | 2010 |
Glial restricted precursor cell transplant with cyclic adenosine monophosphate improved some autonomic functions but resulted in a reduced graft size after spinal cord contusion injury in rats.
Topics: Analysis of Variance; Animals; Autonomic Nervous System; Cell Differentiation; Cyclic AMP; Disease M | 2011 |
Chitosan channels containing spinal cord-derived stem/progenitor cells for repair of subacute spinal cord injury in the rat.
Topics: Animals; Cell Division; Cell Survival; Chitosan; Disease Models, Animal; Ectodysplasins; Glial Fibri | 2010 |
Modulation of lipid peroxidation and mitochondrial function improves neuropathology in Huntington's disease mice.
Topics: Adenosine Triphosphate; Age Factors; Aldehydes; Analysis of Variance; Animals; Cells, Cultured; Cere | 2011 |
Peroxiredoxin-2 protects against 6-hydroxydopamine-induced dopaminergic neurodegeneration via attenuation of the apoptosis signal-regulating kinase (ASK1) signaling cascade.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Animals; Apomorphine; Brain; Cell Differentiation; Ce | 2011 |
SUMO-1 interacts with mutant ataxin-1 and colocalizes to its aggregates in Purkinje cells of SCA1 transgenic mice.
Topics: Animals; Ataxin-1; Ataxins; Cell Line, Transformed; Cell Nucleus; Disease Models, Animal; Gene Expre | 2010 |
Leptin induces proliferation of neuronal progenitors and neuroprotection in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cell Proliferation; Cells, Cultured; Cer | 2011 |
Transcriptional repression of the M channel subunit Kv7.2 in chronic nerve injury.
Topics: Aminopyridines; Analgesics; Analysis of Variance; Anesthetics, Local; Animals; Chronic Disease; Dise | 2011 |
The extracellular matrix glycoprotein tenascin-C promotes locomotor recovery after spinal cord injury in adult zebrafish.
Topics: Analysis of Variance; Animals; Brain Stem; Cell Count; Choline O-Acetyltransferase; Disease Models, | 2011 |
Bone marrow mesenchymal stem cells can improve the motor function of a Huntington's disease rat model.
Topics: Animals; Bone Marrow Cells; Corpus Striatum; Disease Models, Animal; Gene Expression Regulation; Hun | 2011 |
Roles of exogenous and endogenous FGF-2 in animal models of depression.
Topics: Amitriptyline; Analysis of Variance; Animals; Antidepressive Agents; Avoidance Learning; Brain; Depr | 2011 |
Stereologic estimation of hippocampal GluR2/3- and calretinin-immunoreactive hilar neurons (presumptive mossy cells) in two mouse models of temporal lobe epilepsy.
Topics: Animals; Calbindin 2; Cell Count; Disease Models, Animal; Epilepsy, Temporal Lobe; Functional Latera | 2011 |
Soluble tau species, not neurofibrillary aggregates, disrupt neural system integration in a tau transgenic model.
Topics: Animals; Animals, Genetically Modified; Cell Count; Cytoskeletal Proteins; Disease Models, Animal; D | 2011 |
Subarachnoid hemorrhage causes pulmonary endothelial cell apoptosis and neurogenic pulmonary edema in mice.
Topics: Amino Acid Chloromethyl Ketones; Analysis of Variance; Animals; Apoptosis; Caspase 3; Disease Models | 2011 |
α-Syn suppression reverses synaptic and memory defects in a mouse model of dementia with Lewy bodies.
Topics: Acoustic Stimulation; Age Factors; alpha-Synuclein; Analysis of Variance; Animals; Animals, Newborn; | 2011 |
Preconditioning induces sustained neuroprotection by downregulation of adenosine 5'-monophosphate-activated protein kinase.
Topics: Animals; Brain; Brain Infarction; Disease Models, Animal; Down-Regulation; Fluoresceins; HSP72 Heat- | 2012 |
Targeted delivery of bone mesenchymal stem cells by ultrasound destruction of microbubbles promotes kidney recovery in acute kidney injury.
Topics: Acute Kidney Injury; Analysis of Variance; Animals; Blotting, Western; Disease Models, Animal; Indol | 2012 |
Mesenchymal stem cells modified to express interferon-β inhibit the growth of prostate cancer in a mouse model.
Topics: Adenoviridae; Animals; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Genetic Vectors | 2012 |
Mesenchymal stem cells seldomly fuse with hepatocellular carcinoma cells and are mainly distributed in the tumor stroma in mouse models.
Topics: Animals; Bromodeoxyuridine; Carcinoma, Hepatocellular; Cell Differentiation; Cell Fusion; Cell Line, | 2013 |
Genetic deletion of CD36 enhances injury after acute neonatal stroke.
Topics: Animals; Animals, Newborn; Apoptosis; Brain; Caspase 3; CD36 Antigens; Chemokines; Diffusion Magneti | 2012 |
Comparison of three types of stress urinary incontinence rat models: electrocauterization, pudendal denervation, and vaginal distension.
Topics: Actins; Animals; Autonomic Denervation; Dilatation, Pathologic; Disease Models, Animal; Electrocoagu | 2013 |
Insulin growth factor-1 decreases muscle atrophy following denervation.
Topics: Animals; Desmin; Disease Models, Animal; Indoles; Insulin-Like Growth Factor I; Mice; Muscle Contrac | 2002 |
Incorporation and integration of implanted myogenic and stem cells into native myocardial fibers: anatomic basis for functional improvements.
Topics: Animals; Cardiac Surgical Procedures; Cell Differentiation; Cells, Cultured; Disease Models, Animal; | 2002 |
Retinal remodeling triggered by photoreceptor degenerations.
Topics: Aging; Amino Acids; Animals; Animals, Genetically Modified; Cell Death; Cell Movement; Disease Model | 2003 |
Neural stem cells: a potential source for remyelination in neuroinflammatory disease.
Topics: Animals; Bromodeoxyuridine; Carbocyanines; Cell Count; Demyelinating Diseases; Disease Models, Anima | 2003 |
Neonatal vulnerability to ischemia and reperfusion: Cardioplegic arrest causes greater myocardial apoptosis in neonatal lambs than in mature lambs.
Topics: Animals; Animals, Newborn; Apoptosis; Blotting, Western; Caspases; Cytochrome c Group; Disease Model | 2004 |
Intraventricular transplantation of embryonic stem cell-derived neural stem cells in intracerebral hemorrhage rats.
Topics: Animals; Brain; Cell Division; Cell Movement; Cells, Cultured; Cerebral Hemorrhage; Collagenases; Di | 2004 |
The protective effect of hypoxic preconditioning on cortical neuronal cultures is associated with increases in the activity of several antioxidant enzymes.
Topics: Animals; Brain Ischemia; Caspase 3; Caspases; Catalase; Cell Count; Cell Death; Cell Hypoxia; Cells, | 2004 |
Histological parameters for the quantitative assessment of muscular dystrophy in the mdx-mouse.
Topics: Age Factors; Animals; Disease Models, Animal; Histological Techniques; Indoles; Mice; Mice, Inbred C | 2004 |
Transient cerebral ischemia induces site-specific hyperphosphorylation of tau protein.
Topics: Analysis of Variance; Animals; Antibodies, Monoclonal; Blotting, Western; Cell Death; Disease Models | 2004 |
Natural history of neurofibromatosis 1-associated optic nerve glioma in mice.
Topics: Age Factors; Animals; Animals, Newborn; Antigens; Blood Vessels; Disease Models, Animal; Glial Fibri | 2005 |
Grafts of adult subependymal zone neuronal progenitor cells rescue hemiparkinsonian behavioral decline.
Topics: Animals; Behavior, Animal; Bromodeoxyuridine; Cell Count; Cell Differentiation; Cell Movement; Cells | 2005 |
Anti-IL-16 therapy reduces CD4+ T-cell infiltration and improves paralysis and histopathology of relapsing EAE.
Topics: Animals; Antibodies; B-Lymphocytes; Blotting, Western; CD4 Antigens; CD4-Positive T-Lymphocytes; Dis | 2005 |
Restoration of spatial working memory by genetic rescue of GluR-A-deficient mice.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cell Count; Disease Models, Animal; Green Fluoresce | 2005 |
Coxsackievirus targets proliferating neuronal progenitor cells in the neonatal CNS.
Topics: Animals; Animals, Newborn; Bromodeoxyuridine; Cell Count; Cell Proliferation; Central Nervous System | 2005 |
Axonal and extracellular matrix responses to experimental chronic nerve entrapment.
Topics: Animals; Axons; Chondroitin Sulfate Proteoglycans; Chronic Disease; Cricetinae; Disease Models, Anim | 2005 |
Neuroprotective effects of cystamine in aged parkinsonian mice.
Topics: Aging; Animals; Cell Count; Corpus Striatum; Cystamine; Disease Models, Animal; Dopamine Plasma Memb | 2006 |
The preferential mGlu2/3 receptor antagonist, LY341495, reduces the frequency of spike-wave discharges in the WAG/Rij rat model of absence epilepsy.
Topics: Age Factors; Amino Acids; Analysis of Variance; Animals; Baclofen; Behavior, Animal; Blotting, Weste | 2005 |
Neuroprotective mechanisms of curcumin against cerebral ischemia-induced neuronal apoptosis and behavioral deficits.
Topics: Analysis of Variance; Animals; Apoptosis; Astrocytes; Behavior, Animal; Behavioral Symptoms; Brain; | 2005 |
Long-term activation of c-Fos and c-Jun in optic nerve head astrocytes in experimental ocular hypertension in monkeys and after exposure to elevated pressure in vitro.
Topics: Animals; Astrocytes; Blotting, Western; Cell Count; Cell Line; Disease Models, Animal; Female; Gene | 2005 |
Predominant phagocytic activity of resident microglia over hematogenous macrophages following transient focal cerebral ischemia: an investigation using green fluorescent protein transgenic bone marrow chimeric mice.
Topics: Animals; Bone Marrow; Brain; Calcium-Binding Proteins; Cell Count; Diagnostic Imaging; Disease Model | 2005 |
RSEP1 is a novel gene with functional involvement in neuropathic pain behaviour.
Topics: Animals; Behavior, Animal; Blotting, Northern; Brain; Cloning, Molecular; Disease Models, Animal; Gr | 2005 |
Increased severity of acute cerebral ischemic injury correlates with enhanced stem cell induction as well as with predictive behavioral profiling.
Topics: Animals; Behavior, Animal; Bromodeoxyuridine; Cell Count; Disease Models, Animal; Female; Hippocampu | 2004 |
Cell proliferation is influenced by bulbectomy and normalized by imipramine treatment in a region-specific manner.
Topics: Amygdala; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Bromodeoxyuridine; Cell Proli | 2006 |
Homologous transplantation of neural stem cells to the injured spinal cord of mice.
Topics: Animals; Behavior, Animal; Blotting, Northern; Cells, Cultured; Disease Models, Animal; Embryo, Mamm | 2005 |
Graft derived cells with double nuclei in the penumbral region of experimental brain trauma.
Topics: Animals; Brain Injuries; Brain Tissue Transplantation; Bromodeoxyuridine; Cell Count; Cell Division; | 2006 |
Oligodendrocyte progenitor cell (OPC) transplantation is unlikely to offer a means of preventing X-irradiation induced damage in the CNS.
Topics: Animals; Antigens; Caspase 3; Caspases; Cell Count; Central Nervous System Diseases; Disease Models, | 2006 |
Zebrafish lacking Alzheimer presenilin enhancer 2 (Pen-2) demonstrate excessive p53-dependent apoptosis and neuronal loss.
Topics: Alzheimer Disease; Animals; Animals, Genetically Modified; Apoptosis; Blotting, Northern; Blotting, | 2006 |
Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease.
Topics: Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Bone | 2006 |
Apical localization of ITPK1 enhances its ability to be a modifier gene product in a murine tracheal cell model of cystic fibrosis.
Topics: Animals; Cell Line; Cell Membrane; Cell Polarity; Cystic Fibrosis; Disease Models, Animal; Fluoresce | 2006 |
Activated double-stranded RNA-dependent protein kinase and neuronal death in models of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Ac | 2006 |
Monolayered mesenchymal stem cells repair scarred myocardium after myocardial infarction.
Topics: Animals; Animals, Genetically Modified; Cell Differentiation; Cells, Cultured; Disease Models, Anima | 2006 |
Monolayered mesenchymal stem cells repair scarred myocardium after myocardial infarction.
Topics: Animals; Animals, Genetically Modified; Cell Differentiation; Cells, Cultured; Disease Models, Anima | 2006 |
Monolayered mesenchymal stem cells repair scarred myocardium after myocardial infarction.
Topics: Animals; Animals, Genetically Modified; Cell Differentiation; Cells, Cultured; Disease Models, Anima | 2006 |
Monolayered mesenchymal stem cells repair scarred myocardium after myocardial infarction.
Topics: Animals; Animals, Genetically Modified; Cell Differentiation; Cells, Cultured; Disease Models, Anima | 2006 |
Oxygen therapy in permanent brain ischemia: potential and limitations.
Topics: Animals; Animals, Newborn; Brain Infarction; Brain Ischemia; Cell Death; Disease Models, Animal; Imm | 2006 |
Cell transplantation with a catheter-based approach: an efficient method for the treatment of heart failure with multiple lesions.
Topics: Animals; Antibiotics, Antineoplastic; Antimetabolites; Aorta; Bone Marrow Transplantation; Bromodeox | 2006 |
A novel imaging technique for experimental choroidal neovascularization.
Topics: Actins; Animals; Biomarkers; CD11b Antigen; Cell Nucleus; Choroidal Neovascularization; Dextrans; Di | 2006 |
Tyrosine hydroxylase expression is unstable in a human immortalized mesencephalic cell line--studies in vitro and after intracerebral grafting in vivo.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain Tissue Transplantation; Cell Differentiation; | 2007 |
Macrophage depletion alters the blood-nerve barrier without affecting Schwann cell function after neural injury.
Topics: Analysis of Variance; Animals; Blood-Nerve Barrier; Bone Density Conservation Agents; Cell Count; Cl | 2007 |
Injection of mouse and human neural stem cells into neonatal Niemann-Pick A model mice.
Topics: Animals; Animals, Newborn; Cholesterol; Disease Models, Animal; Female; Fetus; Humans; Indoles; Male | 2007 |
Erythropoietin preconditioning suppresses neuronal death following status epilepticus in rats.
Topics: Analysis of Variance; Animals; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; BH3 Interacting | 2007 |
Viral caspase inhibitor p35, but not crmA, is neuroprotective in the ischemic penumbra following experimental stroke.
Topics: Analysis of Variance; Animals; Apoptosis; Apoptosis Inducing Factor; beta-Galactosidase; Bromodeoxyu | 2007 |
Peripheral neuropathy in the twitcher mouse: accumulation of extracellular matrix in the endoneurium and aberrant expression of ion channels.
Topics: Animals; Bone Marrow Transplantation; Disease Models, Animal; Extracellular Matrix; Fibronectins; In | 2008 |
Chronic but not acute treatment with caffeine attenuates traumatic brain injury in the mouse cortical impact model.
Topics: Animals; Brain Injuries; Caffeine; Central Nervous System Stimulants; Cerebral Cortex; Cytokines; Di | 2008 |
Chronic hydrocephalus-induced hypoxia: increased expression of VEGFR-2+ and blood vessel density in hippocampus.
Topics: Analysis of Variance; Animals; Blood Vessels; Chronic Disease; Disease Models, Animal; Dogs; Gene Ex | 2008 |
Effects of neuron-specific ADAM10 modulation in an in vivo model of acute excitotoxic stress.
Topics: ADAM Proteins; ADAM10 Protein; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; | 2008 |
Reimplantation of avulsed lumbosacral ventral roots in the rat ameliorates injury-induced degeneration of primary afferent axon collaterals in the spinal dorsal columns.
Topics: Animals; Calcium-Binding Proteins; Cauda Equina; Disease Models, Animal; Female; Functional Laterali | 2008 |
Leukemia inhibitory factor signaling modulates both central nervous system demyelination and myelin repair.
Topics: Analysis of Variance; Animals; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Female; Gl | 2008 |
Ibuprofen reduces Abeta, hyperphosphorylated tau and memory deficits in Alzheimer mice.
Topics: Adenosine Triphosphatases; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; | 2008 |
Japanese Encephalitis Virus infection induces IL-18 and IL-1beta in microglia and astrocytes: correlation with in vitro cytokine responsiveness of glial cells and subsequent neuronal death.
Topics: Animals; Apoptosis Regulatory Proteins; Astrocytes; Cell Death; Cells, Cultured; Cytokines; Disease | 2008 |
Multiple expression of matrix metalloproteinases in murine neurocysticercosis: Implications for leukocyte migration through multiple central nervous system barriers.
Topics: Animals; Brain; CD11b Antigen; Disease Models, Animal; Female; Indoles; Leukocytosis; Matrix Metallo | 2008 |
Voltage-gated Na+ channel II immunoreactivity is selectively up-regulated in hippocampal interneurons of seizure sensitive gerbils.
Topics: Animals; Disease Models, Animal; Gerbillinae; Hippocampus; Indoles; Interneurons; Seizures; Sodium C | 2008 |
Induction of housekeeping gene expression after subarachnoid hemorrhage in dogs.
Topics: Actins; Animals; Basilar Artery; Cell Proliferation; Connective Tissue; Coronary Vasospasm; Disease | 2008 |
Acute carbon tetrachloride feeding selectively damages large, but not small, cholangiocytes from normal rat liver.
Topics: Animals; Apoptosis; Bicarbonates; Bile; Bile Ducts, Intrahepatic; Carbon Tetrachloride; Cell Divisio | 1999 |