dapi has been researched along with Alexander Disease in 1 studies
DAPI: RN given refers to parent cpd.
Alexander Disease: Rare leukoencephalopathy with infantile-onset accumulation of Rosenthal fibers in the subpial, periventricular, and subependymal zones of the brain. Rosenthal fibers are GLIAL FIBRILLARY ACIDIC PROTEIN aggregates found in ASTROCYTES. Juvenile- and adult-onset types show progressive atrophy of the lower brainstem instead. De novo mutations in the GFAP gene are associated with the disease with propensity for paternal inheritance.
| Excerpt | Relevance | Reference |
|---|---|---|
| "3) DAPI is a reliable marker for RFs and can be used with immunolabeling." | 1.46 | The origin of Rosenthal fibers and their contributions to astrocyte pathology in Alexander disease. ( Goldman, JE; McKhann, GM; Sosunov, AA, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sosunov, AA | 1 |
| McKhann, GM | 1 |
| Goldman, JE | 1 |
1 other study available for dapi and Alexander Disease
| Article | Year |
|---|---|
The origin of Rosenthal fibers and their contributions to astrocyte pathology in Alexander disease.
Topics: Aging; Alexander Disease; alpha-Crystallin B Chain; Animals; Astrocytes; Cerebral Cortex; Child, Pre | 2017 |