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dantrolene and Tremor

dantrolene has been researched along with Tremor in 6 studies

Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.

Tremor: Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE.

Research Excerpts

ExcerptRelevanceReference
"A behavioral preparation that affords concurrent measurement of forelimb force and tremor in rats was used to assess the effects of dantrolene sodium, a muscle relaxant and potential neuroprotective drug."7.71Dantrolene diminishes forelimb force-related tremor at doses that do not decrease operant behavior in the rat. ( Fowler, SC; Stanford, JA, 2002)
"A behavioral preparation that affords concurrent measurement of forelimb force and tremor in rats was used to assess the effects of dantrolene sodium, a muscle relaxant and potential neuroprotective drug."3.71Dantrolene diminishes forelimb force-related tremor at doses that do not decrease operant behavior in the rat. ( Fowler, SC; Stanford, JA, 2002)
"The effects of diazepam, dantrolene and atropine on drug-induced tremors were investigated in mice from the point of view of the tremor frequency."3.67Further studies on quantification of drug-induced tremor in mice: effects of antitremorgenic agents on tremor frequency. ( Hirate, K; Ishida, M; Shinozaki, H, 1985)
"Baclofen is the treatment of choice for spasticity and is usually given in doses of 30 to 80 mg/day, although higher doses may be used."2.37Multiple sclerosis. Current concepts in management. ( Giesser, B, 1985)
"Dantrolene has been recommended for use in horses at risk of developing postanesthetic myopathy."1.28Prophylactic use of dantrolene associated with prolonged postanesthetic recumbency in a horse. ( Boyd, CJ; Dyson, DH; Pascoe, PJ; Valverde, A, 1990)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stanford, JA1
Fowler, SC1
Brvar, M1
Bunc, M1
Valverde, A1
Boyd, CJ1
Dyson, DH1
Pascoe, PJ1
Bone, GH1
Majchrowicz, E1
Martin, PR1
Linnoila, M1
Nutt, DJ1
Giesser, B1
Shinozaki, H1
Hirate, K1
Ishida, M1

Reviews

1 review available for dantrolene and Tremor

ArticleYear
Multiple sclerosis. Current concepts in management.
    Drugs, 1985, Volume: 29, Issue:1

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Baclofen; Dantrolene; Fatigue; Gastrointestina

1985

Other Studies

5 other studies available for dantrolene and Tremor

ArticleYear
Dantrolene diminishes forelimb force-related tremor at doses that do not decrease operant behavior in the rat.
    Experimental and clinical psychopharmacology, 2002, Volume: 10, Issue:4

    Topics: Animals; Behavior, Animal; Conditioning, Operant; Dantrolene; Dose-Response Relationship, Drug; Fore

2002
Video of dantrolene effectiveness on neuroleptic malignant syndrome associated muscular rigidity and tremor.
    Critical care (London, England), 2007, Volume: 11, Issue:3

    Topics: Aged; Dantrolene; Humans; Muscle Relaxants, Central; Muscle Rigidity; Neuroleptic Malignant Syndrome

2007
Prophylactic use of dantrolene associated with prolonged postanesthetic recumbency in a horse.
    Journal of the American Veterinary Medical Association, 1990, Oct-15, Volume: 197, Issue:8

    Topics: Animals; Dantrolene; Horse Diseases; Horses; Male; Malignant Hyperthermia; Muscular Diseases; Postop

1990
A comparison of calcium antagonists and diazepam in reducing ethanol withdrawal tremors.
    Psychopharmacology, 1989, Volume: 99, Issue:3

    Topics: Animals; Brain Chemistry; Calcium Channel Blockers; Dantrolene; Diazepam; Ethanol; Male; Nimodipine;

1989
Further studies on quantification of drug-induced tremor in mice: effects of antitremorgenic agents on tremor frequency.
    Experimental neurology, 1985, Volume: 88, Issue:2

    Topics: Animals; Benzodiazepines; Dantrolene; Dose-Response Relationship, Drug; Harmaline; Male; Mice; Time

1985