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dantrolene and Syndrome

dantrolene has been researched along with Syndrome in 25 studies

Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.

Syndrome: A characteristic symptom complex.

Research Excerpts

ExcerptRelevanceReference
"Malignant syndrome is a disease characterized by high fever, extrapyramidal syndrome and dysautonomia recognized during or at the time of stopping administration of antipsychotic medication and it is the most severe and lethal side effect of antipsychotic medication."5.30[A case of malignant syndrome triggered by the use of haloperidol and chrorpromazine]. ( Fujimoto, K; Konishi, K; Kubota, M; Ogawa, H, 1997)
"However, a fatal malignant hyperthermia-like syndrome (MHLS) with rhabdomyolysis associated with new-onset diabetes mellitus and HHNS in adolescents has been described."1.33Approach to management of malignant hyperthermia-like syndrome in pediatric diabetes mellitus. ( Backeljauw, PF; Crimmins, NA; Kilbane, BJ; Mehta, S; Shanley, TP, 2006)
"Satoyoshi syndrome is a very rare disorder, characterized by progressive painful intermittent muscle spasms beginning in adolescence."1.31[A case of Satoyoshi syndrome complicating marginal gingivitis of the mandible and dislocation of the temporomandibular joint]. ( Matsumura, T; Shinno, S; Yokoe, M, 2002)
"Malignant syndrome is a disease characterized by high fever, extrapyramidal syndrome and dysautonomia recognized during or at the time of stopping administration of antipsychotic medication and it is the most severe and lethal side effect of antipsychotic medication."1.30[A case of malignant syndrome triggered by the use of haloperidol and chrorpromazine]. ( Fujimoto, K; Konishi, K; Kubota, M; Ogawa, H, 1997)
"Dantrolene also has been utilized successfully in NMS on the hypothesis that the syndrome is similar to anesthetic-induced malignant hyperthermia."1.27Therapy of syndrome malin. ( Conner, CS, 1983)
"Malignant hyperthermia is an inherited muscular disorder and a cause of sudden death in afflicted patients."1.26Malignant hyperthermia. A potentially fatal syndrome in orthopaedic patients. ( Barak, AJ; Connolly, JF; Jardon, OM; Wingard, DW, 1979)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199016 (64.00)18.7374
1990's3 (12.00)18.2507
2000's6 (24.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stratman, RC1
Flynn, JD1
Hatton, KW1
Matsumura, T1
Yokoe, M1
Shinno, S1
Hollander, AS1
Olney, RC1
Blackett, PR1
Marshall, BA1
Kilbane, BJ1
Mehta, S1
Backeljauw, PF1
Shanley, TP1
Crimmins, NA1
Jitsuiki, H1
Yamashita, H1
Kozuru, T1
Yamawaki, S1
Delacour, JL1
Daoudal, P1
Chapoutot, JL1
Rocq, B1
Conner, CS1
Paasuke, RT1
Neppe, VM1
Guerin, JM1
Sakai, T1
Hosokawa, S1
Shibasaki, H1
Goto, I1
Kuroiwa, Y1
Sonoda, H1
Murai, Y1
May, DC1
Morris, SW1
Stewart, RM1
Fenton, BJ1
Gaffney, FA1
Manley, SV1
Kelly, AB1
Hodgson, D1
Rosenburg, H1
Hall, GM1
Lucke, JN1
Lister, D1
Konishi, K1
Fujimoto, K1
Kubota, M1
Ogawa, H1
Naito, Y1
Sunohara, N1
Khondkarian, OA1
Zavalishin, IA1
Novikova, VP1
Jardon, OM1
Wingard, DW1
Barak, AJ1
Connolly, JF1
Goldblatt, D1
Satoyoshi, E1
Sahn, SA1

Reviews

7 reviews available for dantrolene and Syndrome

ArticleYear
Malignant hyperthermia: a pharmacogenetic disorder.
    Orthopedics, 2009, Volume: 32, Issue:11

    Topics: Dantrolene; Genetic Predisposition to Disease; Humans; Malignant Hyperthermia; Muscle Relaxants, Cen

2009
Fatal malignant hyperthermia-like syndrome with rhabdomyolysis complicating the presentation of diabetes mellitus in adolescent males.
    Pediatrics, 2003, Volume: 111, Issue:6 Pt 1

    Topics: Adolescent; Dantrolene; Diabetes Mellitus, Type 2; Fatal Outcome; Humans; Hyperglycemic Hyperosmolar

2003
[Drug-induced neuroleptic malignant syndrome].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2007, Aug-10, Volume: 96, Issue:8

    Topics: Antiparkinson Agents; Antipsychotic Agents; Autonomic Nervous System Diseases; Dantrolene; Diagnosis

2007
Malignant hyperthermia--pearls out of swine?
    British journal of anaesthesia, 1980, Volume: 52, Issue:2

    Topics: Animals; Body Temperature; Dantrolene; Disease Models, Animal; Halothane; Magnesium Sulfate; Maligna

1980
[Neuroleptic malignant syndrome-dopamine-serotonin syndrome--the physiopathology, diagnosis, and therapy].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1997, Volume: 99, Issue:10

    Topics: Animals; Appetite Depressants; Dantrolene; Dopamine D2 Receptor Antagonists; Fenfluramine; Humans; M

1997
[Satoyoshi syndrome (disease)].
    Ryoikibetsu shokogun shirizu, 2001, Issue:36

    Topics: Alopecia; Dantrolene; Diagnosis, Differential; Diarrhea; Disease Progression; Humans; Muscle, Skelet

2001
Immunologic diseases of the pleura.
    Clinics in chest medicine, 1985, Volume: 6, Issue:1

    Topics: Adult; Aged; Bromocriptine; Cardiac Surgical Procedures; Collagen Diseases; Dantrolene; Female; Gran

1985

Other Studies

18 other studies available for dantrolene and Syndrome

ArticleYear
[A case of Satoyoshi syndrome complicating marginal gingivitis of the mandible and dislocation of the temporomandibular joint].
    Rinsho shinkeigaku = Clinical neurology, 2002, Volume: 42, Issue:9

    Topics: Adolescent; Bone and Bones; Dantrolene; Gingivitis; Humans; Joint Dislocations; Joints; Male; Mandib

2002
Approach to management of malignant hyperthermia-like syndrome in pediatric diabetes mellitus.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2006, Volume: 7, Issue:2

    Topics: Adolescent; Black or African American; Butyryl-CoA Dehydrogenase; Child; Dantrolene; Diabetes Mellit

2006
[Therapy of neuroleptic malignant syndrome with dantrolene].
    La Nouvelle presse medicale, 1981, Nov-28, Volume: 10, Issue:43

    Topics: Adult; Antipsychotic Agents; Dantrolene; Epilepsy; Humans; Male; Nervous System Diseases; Syndrome

1981
Neuroleptic malignant syndrome.
    British medical journal (Clinical research ed.), 1983, Aug-20, Volume: 287, Issue:6391

    Topics: Adult; Antipsychotic Agents; Dantrolene; Fever; Humans; Male; Syndrome

1983
Therapy of syndrome malin.
    Drug intelligence & clinical pharmacy, 1983, Volume: 17, Issue:9

    Topics: Antipsychotic Agents; Basal Ganglia Diseases; Dantrolene; Fever; Humans; Syndrome

1983
Drugs, heat stroke and dantrolene.
    Canadian Medical Association journal, 1984, Feb-15, Volume: 130, Issue:4

    Topics: Antipsychotic Agents; Dantrolene; Heat Exhaustion; Humans; Phenothiazines; Syndrome

1984
Neuroleptic malignant syndrome.
    Lancet (London, England), 1984, Mar-10, Volume: 1, Issue:8376

    Topics: Antipsychotic Agents; Dantrolene; Fever; Humans; Muscle Rigidity; Syndrome

1984
The neuroleptic malignant syndrome. A priority system.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1984, Mar-31, Volume: 65, Issue:13

    Topics: Amantadine; Antipsychotic Agents; Basal Ganglia Diseases; Bromocriptine; Consciousness Disorders; Da

1984
Update in neuroleptic malignant syndrome.
    Archives of internal medicine, 1983, Volume: 143, Issue:5

    Topics: Dantrolene; Humans; Muscular Diseases; Syndrome

1983
Syndrome of continuous muscle-fiber activity: increased CSF GABA and effect of dantrolene.
    Neurology, 1983, Volume: 33, Issue:4

    Topics: Adolescent; Dantrolene; Electromyography; Female; gamma-Aminobutyric Acid; H-Reflex; Humans; Myotoni

1983
Neuroleptic malignant syndrome: response to dantrolene sodium.
    Annals of internal medicine, 1983, Volume: 98, Issue:2

    Topics: Dantrolene; Fever; Haloperidol; Humans; Male; Middle Aged; Muscle Rigidity; Syndrome

1983
Malignant hyperthermia-like reactions in three anesthetized horses.
    Journal of the American Veterinary Medical Association, 1983, Jul-01, Volume: 183, Issue:1

    Topics: Anesthesia, General; Animals; Dantrolene; Female; Halothane; Horse Diseases; Horses; Male; Malignant

1983
Malignant hyperpyrexia.
    The American journal of nursing, 1981, Volume: 81, Issue:8

    Topics: Adult; Anesthetics; Animals; Cryotherapy; Dantrolene; Female; Humans; Male; Malignant Hyperthermia;

1981
[A case of malignant syndrome triggered by the use of haloperidol and chrorpromazine].
    Masui. The Japanese journal of anesthesiology, 1997, Volume: 46, Issue:4

    Topics: Adult; Antipsychotic Agents; Anxiety; Autonomic Nervous System Diseases; Basal Ganglia Diseases; Chl

1997
[Muscle spasms in patients with amyotrophic lateral sclerosis (clinico-electromyographnic analysis)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1979, Volume: 79, Issue:7

    Topics: Amyotrophic Lateral Sclerosis; Carisoprodol; Dantrolene; Electromyography; Humans; Motor Neurons; Mo

1979
Malignant hyperthermia. A potentially fatal syndrome in orthopaedic patients.
    The Journal of bone and joint surgery. American volume, 1979, Volume: 61, Issue:7

    Topics: Adult; Animals; Child, Preschool; Dantrolene; Female; Genes, Dominant; Humans; Male; Malignant Hyper

1979
Treatment of amyotrophic lateral sclerosis.
    Advances in neurology, 1977, Volume: 17

    Topics: Aging; Amitriptyline; Amyotrophic Lateral Sclerosis; Baclofen; Braces; Dantrolene; Deglutition Disor

1977
[Satoyoshi's syndrome: a syndrome of progressive muscle spasm, alopecia, and diarrhea].
    Nihon rinsho. Japanese journal of clinical medicine, 1990, Volume: 48, Issue:7

    Topics: Adolescent; Adult; Alopecia; Baclofen; Child; Dantrolene; Diarrhea; Humans; Male; Muscle Spasticity;

1990