dantrolene has been researched along with Swine Diseases in 11 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
Swine Diseases: Diseases of domestic swine and of the wild boar of the genus Sus.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Muscle metabolism was studied in pigs of different halothane genotypes by taking blood and muscle biopsy samples during a 45-min preslaughter period of anesthesia." | 3.69 | Effect of dantrolene treatment on muscle metabolism and meat quality of anesthetized pigs of different halothane genotypes. ( Klont, RE; Lambooy, E; van Logtestijn, JG, 1994) |
| "The authors examined the thesis that a dose of dantrolene producing 95 per cent of maximal muscle relaxation (ED95) would effectively prevent or treat malignant hyperthermia (MH)." | 3.66 | Dantrolene dose response in malignant hyperthermia-susceptible (MHS) swine: method to obtain prophylaxis and therapeusis. ( Flewellen, EH; Nelson, TE, 1980) |
| "A case of porcine malignant hyperthermia (MH) is reported, which occurred during a cardiological animal experiment under general anaesthesia using isoflurane as inhalational anaesthetic." | 1.29 | [Malignant hyperthermia in swine during isoflurane anesthesia]. ( Bötel, C; Krohn, S; Paul, T; Strauss, JM; Sümpelmann, R; Zimmermann, M, 1994) |
| "treatment with dantrolene." | 1.29 | The reduction of skeletal muscle lesions after experimental stress in stress-susceptible pigs protected with dantrolene. ( Bjurström, S; Carlsten, J; Jönsson, L, 1995) |
| "Malignant hyperthermia is an inherited muscular disorder and a cause of sudden death in afflicted patients." | 1.26 | Malignant hyperthermia. A potentially fatal syndrome in orthopaedic patients. ( Barak, AJ; Connolly, JF; Jardon, OM; Wingard, DW, 1979) |
| "The effect of dantrolene on porcine malignant hyperthermia in the Pietrain pig was studied." | 1.26 | Treatment of porcine malignant hyperpyrexia. The successful use of dantrolene in the Pietrain pig. ( Hall, GM; Lister, D; Lucke, JN, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (72.73) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nelson, TE | 2 |
| Flewellen, EH | 2 |
| Manley, SV | 1 |
| Kelly, AB | 1 |
| Hodgson, D | 1 |
| Denborough, MA | 1 |
| Klont, RE | 1 |
| Lambooy, E | 1 |
| van Logtestijn, JG | 1 |
| Sümpelmann, R | 1 |
| Bötel, C | 1 |
| Zimmermann, M | 1 |
| Krohn, S | 1 |
| Strauss, JM | 1 |
| Paul, T | 1 |
| Bjurström, S | 1 |
| Carlsten, J | 1 |
| Jönsson, L | 1 |
| Lucke, JN | 2 |
| Hall, GM | 2 |
| Lister, D | 2 |
| Jardon, OM | 1 |
| Wingard, DW | 1 |
| Barak, AJ | 1 |
| Connolly, JF | 1 |
| Adnet, P | 1 |
| Krivosic-Horber, R | 1 |
| Guevart, E | 1 |
| Theunynck, D | 1 |
| Vincent, A | 1 |
3 reviews available for dantrolene and Swine Diseases
| Article | Year |
|---|---|
Current concepts. The malignant hyperthermia syndrome.
Topics: Animals; Dantrolene; Disease Models, Animal; Halothane; Humans; Malignant Hyperthermia; Muscles; Swi | 1983 |
The pathopharmacology of malignant hyperpyrexia.
Topics: Adenylate Kinase; Anesthesia, General; Animals; Blood Platelets; Calcium; Catecholamines; Cats; Dant | 1980 |
Anaesthesia of pigs sensitive to malignant hyperthermia.
Topics: Anesthesia; Animals; Barbiturates; Body Temperature; Cardiac Output; Dantrolene; Halothane; Heart Ra | 1977 |
8 other studies available for dantrolene and Swine Diseases
| Article | Year |
|---|---|
Malignant hyperthermia-like reactions in three anesthetized horses.
Topics: Anesthesia, General; Animals; Dantrolene; Female; Halothane; Horse Diseases; Horses; Male; Malignant | 1983 |
Dantrolene dose response in malignant hyperthermia-susceptible (MHS) swine: method to obtain prophylaxis and therapeusis.
Topics: Animals; Dantrolene; Dose-Response Relationship, Drug; Female; Hydrogen-Ion Concentration; Lactates; | 1980 |
Effect of dantrolene treatment on muscle metabolism and meat quality of anesthetized pigs of different halothane genotypes.
Topics: Anesthesia; Animals; Biopsy, Needle; Calcium; Creatine; Dantrolene; Genotype; Glycogen; Halothane; H | 1994 |
[Malignant hyperthermia in swine during isoflurane anesthesia].
Topics: Anesthesia, Inhalation; Animals; Carbon Dioxide; Dantrolene; Isoflurane; Malignant Hyperthermia; Swi | 1994 |
The reduction of skeletal muscle lesions after experimental stress in stress-susceptible pigs protected with dantrolene.
Topics: Animals; Dantrolene; Female; Male; Malignant Hyperthermia; Muscle Relaxants, Central; Muscle, Skelet | 1995 |
Malignant hyperthermia. A potentially fatal syndrome in orthopaedic patients.
Topics: Adult; Animals; Child, Preschool; Dantrolene; Female; Genes, Dominant; Humans; Male; Malignant Hyper | 1979 |
Treatment of porcine malignant hyperpyrexia. The successful use of dantrolene in the Pietrain pig.
Topics: Animals; Dantrolene; Hydantoins; Malignant Hyperthermia; Swine; Swine Diseases | 1977 |
[Experimental study of dantrolene sodium in anesthetic malignant hyperthermia in the pietrain-strain pig].
Topics: Animals; Dantrolene; Malignant Hyperthermia; Swine; Swine Diseases | 1986 |