dantrolene has been researched along with Spinal Cord Diseases in 5 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
Spinal Cord Diseases: Pathologic conditions which feature SPINAL CORD damage or dysfunction, including disorders involving the meninges and perimeningeal spaces surrounding the spinal cord. Traumatic injuries, vascular diseases, infections, and inflammatory/autoimmune processes may affect the spinal cord.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In 25 patients with spasticity, pharmacokinetics and effects of dantrolene sodium were investigated after prolonged administration." | 1.26 | The effect of dantrolene sodium in relation to blood levels in spastic patients after prolonged administration. ( Agoston, S; Bakker, H; Kok, JJ; Meyler, WJ; Wesseling, H, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Meyler, WJ | 1 |
| Bakker, H | 1 |
| Kok, JJ | 1 |
| Agoston, S | 1 |
| Wesseling, H | 1 |
| Weiser, R | 1 |
| Terenty, T | 1 |
| Hudgson, P | 1 |
| Weightman, D | 1 |
| Teague, CT | 1 |
| Merrill, DC | 1 |
| Freedman, W | 1 |
| Herman, R | 1 |
| Monster, AW | 1 |
2 trials available for dantrolene and Spinal Cord Diseases
| Article | Year |
|---|---|
Dantrolene sodium in the treatment of spasticity in chronic spinal cord disease.
Topics: Adult; Aged; Chronic Disease; Clinical Trials as Topic; Dantrolene; Double-Blind Method; Female; Hum | 1978 |
Spasticity and the effect of dantrolene sodium.
Topics: Adult; Ankle Joint; Cerebrovascular Disorders; Clinical Trials as Topic; Dantrolene; Dose-Response R | 1974 |
3 other studies available for dantrolene and Spinal Cord Diseases
| Article | Year |
|---|---|
The effect of dantrolene sodium in relation to blood levels in spastic patients after prolonged administration.
Topics: Adult; Aged; Brain Concussion; Dantrolene; Dose-Response Relationship, Drug; Female; Humans; Male; M | 1981 |
Effect of baclofen and dantrolene on bladder stimulator-induced detrusor-sphincter dyssynergia in dogs.
Topics: Aminobutyrates; Animals; Baclofen; Dantrolene; Depression, Chemical; Dogs; Electric Stimulation; Fem | 1978 |
Inhibition of electromyographic activity in human triceps surae muscles during sinusoidal rotation of the foot.
Topics: Adult; Ankle; Dantrolene; Electromyography; Foot; Hemiplegia; Humans; Models, Biological; Motor Neur | 1975 |