dantrolene has been researched along with Schizophrenia in 18 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A case of heatstroke is reported in a 32-year-old man diagnosed with schizophrenia and on clozapine monotherapy." | 7.72 | Heat stroke in schizophrenia during clozapine treatment: rapid recognition and management. ( Kerwin, RW; Osborne, S; Sainz-Fuertes, R, 2004) |
| "We present the case of a 42-year-old male with a history of schizophrenia who developed signs and symptoms consistent with Neuroleptic Malignant Syndrome (NMS) after 3 weeks of treatment with Olanzapine." | 7.70 | Neuroleptic malignant syndrome associated with olanzapine therapy: a case report. ( Privette, T; Stanfield, SC, 2000) |
| "Clozapine is an atypical neuroleptic drug that was initially thought not to cause neuroleptic malignant syndrome (NMS)." | 7.68 | Neuroleptic malignant syndrome and clozapine. ( Minnema, AM; Reddig, S; Tandon, R, 1993) |
| "A case of heatstroke is reported in a 32-year-old man diagnosed with schizophrenia and on clozapine monotherapy." | 3.72 | Heat stroke in schizophrenia during clozapine treatment: rapid recognition and management. ( Kerwin, RW; Osborne, S; Sainz-Fuertes, R, 2004) |
| "We present the case of a 42-year-old male with a history of schizophrenia who developed signs and symptoms consistent with Neuroleptic Malignant Syndrome (NMS) after 3 weeks of treatment with Olanzapine." | 3.70 | Neuroleptic malignant syndrome associated with olanzapine therapy: a case report. ( Privette, T; Stanfield, SC, 2000) |
| "Clozapine is an atypical neuroleptic drug that was initially thought not to cause neuroleptic malignant syndrome (NMS)." | 3.68 | Neuroleptic malignant syndrome and clozapine. ( Minnema, AM; Reddig, S; Tandon, R, 1993) |
| "A patient with chronic schizophrenia treated with fluphenazine developed neuroleptic malignant syndrome, characterized by fever, obtundation, rigidity, and tremulousness." | 3.66 | Neuroleptic malignant syndrome: successful treatment with dantrolene and bromocriptine. ( Adler, S; Coyle, J; Granato, JE; Karim, AH; Krumholz, A; Ringel, A; Stern, BJ, 1983) |
| " Muscle rigidity was not affected by etybenzatropine or diazepam, but dantrolene, a direct-acting skeletal muscle relaxant, provided muscle relaxation with a concomitant decrease of fever and serum creatine kinase." | 3.66 | Beneficial effects of dantrolene in the treatment of neuroleptic malignant syndrome: a report of two cases. ( Bismuth, C; Conso, F; de Rohan-Chabot, P; Elkharrat, D; Gajdos, P; Goulon, M, 1983) |
| "Neuroleptic malignant syndrome is a rare but serious adverse effect of antipsychotic medication." | 2.37 | Neuroleptic malignant syndrome. ( Levenson, JL, 1985) |
| "She was diagnosed with neuroleptic malignant syndrome (NMS) induced by the discontinuation of psychotropic drugs." | 1.72 | [A case of neuroleptic malignant syndrome caused by discontinuation of psychotropic drugs]. ( Suzuki, M; Takahashi, Y; Togashi, A; Yaguchi, H; Yaguchi, M, 2022) |
| "On arrival, the Japan coma scale, pulse, respiratory rate, body temperature, and Sp(O2) were 300, 114 beats x min(-1), 26 breaths x min(-1), 39." | 1.38 | [Comatose patient with neuroleptic malignant syndrome brought by ambulance]. ( Kuroda, Y; Takinami, Y, 2012) |
| "Dantrolene sodium iv was administered for three days." | 1.29 | Neuroleptic malignant-like syndrome: a complication of acute organophosphate poisoning. ( Arai, T; Hatakenaka, S; Ochi, G; Tokuoka, H; Watanabe, K, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (33.33) | 18.7374 |
| 1990's | 6 (33.33) | 18.2507 |
| 2000's | 3 (16.67) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 2 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Takahashi, Y | 1 |
| Yaguchi, M | 1 |
| Yaguchi, H | 1 |
| Togashi, A | 1 |
| Suzuki, M | 1 |
| Kajani, R | 1 |
| Apramian, A | 1 |
| Vega, A | 1 |
| Ubhayakar, N | 1 |
| Xu, P | 1 |
| Liu, A | 1 |
| Takinami, Y | 1 |
| Kuroda, Y | 1 |
| Kerwin, RW | 1 |
| Osborne, S | 1 |
| Sainz-Fuertes, R | 1 |
| Smidt, MH | 1 |
| Collumbien, EC | 1 |
| Coons, DJ | 1 |
| Hillman, FJ | 1 |
| Marshall, RW | 1 |
| Granato, JE | 1 |
| Stern, BJ | 1 |
| Ringel, A | 1 |
| Karim, AH | 1 |
| Krumholz, A | 1 |
| Coyle, J | 1 |
| Adler, S | 1 |
| Goulon, M | 1 |
| de Rohan-Chabot, P | 1 |
| Elkharrat, D | 1 |
| Gajdos, P | 1 |
| Bismuth, C | 1 |
| Conso, F | 1 |
| Nisijima, K | 2 |
| Matoba, M | 1 |
| Ishiguro, T | 2 |
| Reddig, S | 1 |
| Minnema, AM | 1 |
| Tandon, R | 1 |
| Velamoor, VR | 1 |
| Swamy, GN | 1 |
| Parmar, RS | 1 |
| Williamson, P | 1 |
| Caroff, SN | 1 |
| Ochi, G | 1 |
| Watanabe, K | 1 |
| Tokuoka, H | 1 |
| Hatakenaka, S | 1 |
| Arai, T | 1 |
| Noguti, M | 1 |
| Stanfield, SC | 1 |
| Privette, T | 1 |
| Sczesni, B | 2 |
| Becker, H | 1 |
| Schröder, J | 1 |
| Bittkau, S | 1 |
| von Baumgarten, F | 1 |
| Truong, DD | 2 |
| Przuntek, H | 1 |
| Levenson, JL | 1 |
| Fahn, S | 1 |
| Gross, J | 1 |
| Donovan, K | 1 |
| van Bakel, A | 1 |
| Wiley, MK | 1 |
| Lesser, MS | 1 |
| Kahan, M | 1 |
| Brenner, R | 1 |
| Nayak, D | 1 |
2 reviews available for dantrolene and Schizophrenia
| Article | Year |
|---|---|
Management of suspected neuroleptic malignant syndrome.
Topics: Adult; Antipsychotic Agents; Combined Modality Therapy; Dantrolene; Dopamine Agonists; Electroconvul | 1995 |
Neuroleptic malignant syndrome.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Bromocriptine; Child; Dantrol | 1985 |
16 other studies available for dantrolene and Schizophrenia
| Article | Year |
|---|---|
[A case of neuroleptic malignant syndrome caused by discontinuation of psychotropic drugs].
Topics: Aged; Antipsychotic Agents; Dantrolene; Female; Humans; Neuroleptic Malignant Syndrome; Psychotropic | 2022 |
Neuroleptic malignant syndrome in a COVID-19 patient.
Topics: Acute Kidney Injury; Antipsychotic Agents; Betacoronavirus; Bromocriptine; C-Reactive Protein; Coron | 2020 |
[Comatose patient with neuroleptic malignant syndrome brought by ambulance].
Topics: Adult; Ambulances; Basal Ganglia Diseases; Chlorpromazine; Coma; Dantrolene; Drug Overdose; Female; | 2012 |
Heat stroke in schizophrenia during clozapine treatment: rapid recognition and management.
Topics: Adult; Antipsychotic Agents; Clozapine; Dantrolene; Heat Stroke; Humans; Male; Muscle Relaxants, Cen | 2004 |
[A cocaine-induced variant of the neuroleptic malignant syndrome. A case study].
Topics: Bromocriptine; Cocaine; Dantrolene; Dopamine Agonists; Humans; Male; Middle Aged; Muscle Relaxants, | 2006 |
Treatment of neuroleptic malignant syndrome with dantrolene sodium: a case report.
Topics: Adult; Antipsychotic Agents; Body Temperature; Dantrolene; Dose-Response Relationship, Drug; Dyskine | 1982 |
Neuroleptic malignant syndrome: successful treatment with dantrolene and bromocriptine.
Topics: Adult; Basal Ganglia Diseases; Bromocriptine; Dantrolene; Drug Therapy, Combination; Fluphenazine; H | 1983 |
Beneficial effects of dantrolene in the treatment of neuroleptic malignant syndrome: a report of two cases.
Topics: Adolescent; Adult; Basal Ganglia Diseases; Dantrolene; Fever; Haloperidol; Humans; Male; Muscle Rigi | 1983 |
Single photon emission computed tomography with 123I-IMP in three cases of the neuroleptic malignant syndrome.
Topics: Adult; Amphetamines; Antipsychotic Agents; Basal Ganglia; Brain; Dantrolene; Dose-Response Relations | 1994 |
Neuroleptic malignant syndrome and clozapine.
Topics: Adult; Antipsychotic Agents; Bromocriptine; Clozapine; Dantrolene; Diagnosis, Differential; Fever; H | 1993 |
Neuroleptic malignant-like syndrome: a complication of acute organophosphate poisoning.
Topics: Atropine; Cholinesterase Reactivators; Cholinesterases; Dantrolene; Female; Humans; Middle Aged; Mio | 1995 |
Intravenous injection of levodopa is more effective than dantrolene as therapy for neuroleptic malignant syndrome.
Topics: Adult; Dantrolene; Dopamine Agents; Female; Humans; Injections, Intravenous; Levodopa; Male; Muscle | 1997 |
Neuroleptic malignant syndrome associated with olanzapine therapy: a case report.
Topics: Adult; Anti-Bacterial Agents; Antipsychotic Agents; Benzodiazepines; Bromocriptine; Combined Modalit | 2000 |
[Diagnostic and therapeutic aspects of neuroleptic malignant syndrome based on 12 cases].
Topics: Adult; Amantadine; Antipsychotic Agents; Bromocriptine; Dantrolene; Depressive Disorder; Diazepam; D | 1991 |
[Neuroleptic malignant syndrome (dopamine-dependent malignant hyperthermia). 4 different cases].
Topics: Adult; Aged; Antipsychotic Agents; Brain; Bromocriptine; Dantrolene; Humans; Male; Middle Aged; Neur | 1988 |
Dantrolene sodium as a possible prophylactic agent against N.M.S.
Topics: Adult; Dantrolene; Fluphenazine; Humans; Male; Neuroleptic Malignant Syndrome; Recurrence; Schizophr | 1986 |