dantrolene has been researched along with Pregnancy in 20 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| " No adverse effect of dantrolene sodium was detected by extensive testing of the fetus and neonate." | 5.27 | Dantrolene in pregnancy: lack of adverse effects on the fetus and newborn infant. ( Andrews, J; Britt, B; Gare, D; Shime, J, 1988) |
| "Oral dantrolene was given during the first nine postoperative days." | 5.27 | [Oral dantrolene in a parturient with myotonic dystrophy and susceptibility to malignant hyperthermia]. ( Achilli-Cornesse, E; Houvenaeghel, M; Jullian-Papouin, H; Manelli, JC; Martin-Meyssonier, A, 1988) |
| " Hypotension was treated with ephedrine." | 3.69 | Anaesthesia for caesarean delivery of a malignant hyperthermia susceptible parturient. ( Lucy, SJ, 1994) |
| " Discussion centres around the problems of diagnosis of malignant hyperthermia susceptibility in pregnancy, the differential diagnosis and management of fever and tachycardia in a MHS parturient during labour and the use of dantrolene prophylaxis." | 3.67 | The anaesthetic management of the malignant hyperthermia susceptible parturient. ( Douglas, MJ; McMorland, GH, 1986) |
| "We found that maintaining a malignant hyperthermia cart in every maternity unit in the United States would reduce morbidity and mortality costs by $3,304,641 per year nationally but would cost $5,927,040 annually." | 1.48 | Cost-benefit Analysis of Maintaining a Fully Stocked Malignant Hyperthermia Cart versus an Initial Dantrolene Treatment Dose for Maternity Units. ( Carvalho, B; Ho, PT; Macario, A; Riley, ET; Sun, EC, 2018) |
| "A case of susceptibility to malignant hyperthermia, diagnosed by muscle biopsy during the first trimester of pregnancy, is presented." | 1.28 | Diagnosis and management of susceptibility to malignant hyperthermia in pregnancy. ( Botti, JJ; Ingardia, CJ; Sorosky, JI, 1989) |
| " No adverse effect of dantrolene sodium was detected by extensive testing of the fetus and neonate." | 1.27 | Dantrolene in pregnancy: lack of adverse effects on the fetus and newborn infant. ( Andrews, J; Britt, B; Gare, D; Shime, J, 1988) |
| "Oral dantrolene was given during the first nine postoperative days." | 1.27 | [Oral dantrolene in a parturient with myotonic dystrophy and susceptibility to malignant hyperthermia]. ( Achilli-Cornesse, E; Houvenaeghel, M; Jullian-Papouin, H; Manelli, JC; Martin-Meyssonier, A, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (55.00) | 18.7374 |
| 1990's | 6 (30.00) | 18.2507 |
| 2000's | 1 (5.00) | 29.6817 |
| 2010's | 2 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ho, PT | 1 |
| Carvalho, B | 1 |
| Sun, EC | 1 |
| Macario, A | 1 |
| Riley, ET | 1 |
| Lee, JH | 1 |
| Zhang, J | 1 |
| Flores, L | 1 |
| Rose, JC | 1 |
| Massmann, GA | 1 |
| Figueroa, JP | 1 |
| Wang, H | 1 |
| Yuan, G | 1 |
| Prabhakar, NR | 1 |
| Boswell, M | 1 |
| Katz, DM | 1 |
| Cupryn, JP | 1 |
| Kennedy, A | 1 |
| Byrick, RJ | 1 |
| Morison, DH | 1 |
| DeLisa, JA | 1 |
| Little, J | 1 |
| Lucy, SJ | 1 |
| Goto, S | 1 |
| Ogata, K | 1 |
| Fujie, T | 1 |
| Fujigaki, T | 1 |
| Nakamura, H | 1 |
| Yukinari, T | 1 |
| Shibata, O | 1 |
| Sánchez-Olea, R | 1 |
| Pasantes-Morales, H | 1 |
| Schousboe, A | 1 |
| Ben Abraham, R | 1 |
| Cahana, A | 1 |
| Krivosic-Horber, RM | 1 |
| Perel, A | 1 |
| Fricker, RM | 1 |
| Hoerauf, KH | 1 |
| Drewe, J | 1 |
| Kress, HG | 1 |
| Taylor, MJ | 1 |
| Clark, CL | 1 |
| Sorosky, JI | 1 |
| Ingardia, CJ | 1 |
| Botti, JJ | 1 |
| Shime, J | 1 |
| Gare, D | 1 |
| Andrews, J | 1 |
| Britt, B | 1 |
| Houvenaeghel, M | 1 |
| Achilli-Cornesse, E | 1 |
| Jullian-Papouin, H | 1 |
| Martin-Meyssonier, A | 1 |
| Manelli, JC | 1 |
| Craft, JB | 1 |
| Goldberg, NH | 1 |
| Lim, M | 1 |
| Landsberger, E | 1 |
| Mazel, P | 1 |
| Abramson, FP | 1 |
| Stolte, AL | 1 |
| Braswell, ME | 1 |
| Farina, JP | 1 |
| Douglas, MJ | 1 |
| McMorland, GH | 1 |
| Weingarten, AE | 1 |
| Korsh, JI | 1 |
| Neuman, GG | 1 |
| Stern, SB | 1 |
| Kaplan, RF | 1 |
| Kellner, KR | 1 |
| Kiwitt, A | 1 |
| Pingel, E | 1 |
1 review available for dantrolene and Pregnancy
| Article | Year |
|---|---|
Malignant hyperthermia susceptibility: anaesthetic implications and risk stratification.
Topics: Adolescent; Anesthesia; Anesthesia, Obstetrical; Cesarean Section; Child; Child, Preschool; Contrain | 1997 |
19 other studies available for dantrolene and Pregnancy
| Article | Year |
|---|---|
Cost-benefit Analysis of Maintaining a Fully Stocked Malignant Hyperthermia Cart versus an Initial Dantrolene Treatment Dose for Maternity Units.
Topics: Cost-Benefit Analysis; Dantrolene; Decision Trees; Dose-Response Relationship, Drug; Female; Humans; | 2018 |
Antenatal betamethasone has a sex-dependent effect on the in vivo response to endothelin in adult sheep.
Topics: Animals; Anti-Inflammatory Agents; Betamethasone; Blood Pressure; Dantrolene; Dose-Response Relation | 2013 |
Secretion of brain-derived neurotrophic factor from PC12 cells in response to oxidative stress requires autocrine dopamine signaling.
Topics: Animals; Autocrine Communication; Boron Compounds; Brain; Brain-Derived Neurotrophic Factor; Butacla | 2006 |
Malignant hyperthermia in pregnancy.
Topics: Administration, Oral; Anesthesia, Obstetrical; Cesarean Section; Dantrolene; Female; Humans; Infant, | 1984 |
Placental transfer of dantrolene.
Topics: Anesthesia, Obstetrical; Dantrolene; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Pregn | 1983 |
Managing spasticity.
Topics: Adult; Baclofen; Child, Preschool; Cold Temperature; Dantrolene; Diazepam; Female; Humans; Muscle Sp | 1982 |
Anaesthesia for caesarean delivery of a malignant hyperthermia susceptible parturient.
Topics: Adult; Anesthesia, Inhalation; Anesthesia, Obstetrical; Anesthesia, Spinal; Bupivacaine; Cesarean Se | 1994 |
[Caesarean section in a patient with past history of fulminant malignant hyperthermia].
Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Cesarean Section; Dantrolene; Disease Susceptibi | 1993 |
Neurons respond to hyposmotic conditions by an increase in intracellular free calcium.
Topics: Aniline Compounds; Animals; Calcium; Calcium Channel Blockers; Cerebral Cortex; Chelating Agents; Da | 1993 |
Secretion of dantrolene into breast milk after acute therapy of a suspected malignant hyperthermia crisis during cesarean section.
Topics: Adult; Cesarean Section; Dantrolene; Female; Humans; Lactation; Malignant Hyperthermia; Milk, Human; | 1998 |
Evidence that basal secretion of relaxin by individual cultured large luteal cells is influenced by mobilization of intracellular calcium: analysis by a reverse hemolytic plaque assay.
Topics: Animals; Calcium; Cell Compartmentation; Cells, Cultured; Corpus Luteum; Dantrolene; Endoplasmic Ret | 1992 |
Diagnosis and management of susceptibility to malignant hyperthermia in pregnancy.
Topics: Adult; Anesthesia, Obstetrical; Biopsy; Dantrolene; Delivery, Obstetric; Disease Susceptibility; Fem | 1989 |
Dantrolene in pregnancy: lack of adverse effects on the fetus and newborn infant.
Topics: Administration, Oral; Apgar Score; Dantrolene; Female; Fetus; Heart Rate, Fetal; Humans; Infant, New | 1988 |
[Oral dantrolene in a parturient with myotonic dystrophy and susceptibility to malignant hyperthermia].
Topics: Administration, Oral; Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Cesarean Section; Creati | 1988 |
Cardiovascular effects and placental passage of dantrolene in the maternal-fetal sheep model.
Topics: Acid-Base Equilibrium; Animals; Dantrolene; Female; Fetus; Hemodynamics; Maternal-Fetal Exchange; Pr | 1988 |
The anaesthetic management of the malignant hyperthermia susceptible parturient.
Topics: Analgesics; Anesthesia; Anesthesiology; Cesarean Section; Dantrolene; Female; Humans; Malignant Hype | 1986 |
Postpartum uterine atony after intravenous dantrolene.
Topics: Adult; Cesarean Section; Dantrolene; Female; Humans; Injections, Intravenous; Malignant Hyperthermia | 1987 |
More on malignant hyperthermia during delivery.
Topics: Dantrolene; Female; Humans; Labor, Obstetric; Malignant Hyperthermia; Pregnancy | 1985 |
[A case of malignant hyperthermia in operative obstetrics].
Topics: Adult; Cesarean Section; Combined Modality Therapy; Dantrolene; Female; Humans; Infant, Newborn; Mal | 1985 |