Page last updated: 2024-10-25
dantrolene and Polyneuropathy, Acquired
dantrolene has been researched along with Polyneuropathy, Acquired in 1 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|
| "Paclitaxel treatment resulted in a peripheral neuropathy that affected the two hindpaws." | 1.35 | Different antinociceptive effects of botulinum toxin type A in inflammatory and peripheral polyneuropathic rat models. ( Auguet, M; Chabrier, PE; Favre-Guilmard, C, 2009) |
Research
Studies (1)
| Timeframe | Studies, this research(%) | All Research% |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|
| Favre-Guilmard, C | 1 |
| Auguet, M | 1 |
| Chabrier, PE | 1 |
Clinical Trials (1)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status |
|---|
| Botulinum Toxin A for the Treatment of Chemotherapy Induced Peripheral Neuropathy[NCT03571334] | Phase 2 | 40 participants (Anticipated) | Interventional | 2020-07-08 | Recruiting |
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Other Studies
1 other study available for dantrolene and Polyneuropathy, Acquired