Page last updated: 2024-10-25

dantrolene and Poisoning

dantrolene has been researched along with Poisoning in 9 studies

Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.

Poisoning: Used with drugs, chemicals, and industrial materials for human or animal poisoning, acute or chronic, whether the poisoning is accidental, occupational, suicidal, by medication error, or by environmental exposure.

Research Excerpts

ExcerptRelevanceReference
" Additionally, we discuss the use of dantrolene in dinitrophenol poisoning and question whether current Toxbase/UK National Poison Information Service treatment guidelines regarding the indication and dosing of this drug, the only relatively specific treatment in dinitrophenol poisoning presently recommended, could be revised."5.36'Fatal 2,4-dinitrophenol poisoning... coming to a hospital near you'. ( Narasimhaiah, R; Siegmueller, C, 2010)
" Additionally, we discuss the use of dantrolene in dinitrophenol poisoning and question whether current Toxbase/UK National Poison Information Service treatment guidelines regarding the indication and dosing of this drug, the only relatively specific treatment in dinitrophenol poisoning presently recommended, could be revised."1.36'Fatal 2,4-dinitrophenol poisoning... coming to a hospital near you'. ( Narasimhaiah, R; Siegmueller, C, 2010)
"Dantrolene sodium iv was administered for three days."1.29Neuroleptic malignant-like syndrome: a complication of acute organophosphate poisoning. ( Arai, T; Hatakenaka, S; Ochi, G; Tokuoka, H; Watanabe, K, 1995)
"Dantrolene appears to be an effective treatment for phenelzine toxicity manifested by a hypermetabolic state."1.27Phenelzine toxicity responsive to dantrolene. ( Bennetts, M; Kozachuk, WE; Salanga, VD; Verrilli, MR, 1987)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's5 (55.56)18.2507
2000's1 (11.11)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Van Schoor, J1
Khanderia, E1
Thorniley, A1
Siegmueller, C1
Narasimhaiah, R1
Barker, K1
Seger, D1
Kumar, S1
Wake, D1
Parr, MJ1
Craft, TM1
Ochi, G1
Watanabe, K1
Tokuoka, H1
Hatakenaka, S1
Arai, T1
Hall, AP1
Lyburn, ID1
Spears, FD1
Riley, B1
MacConnachie, AM1
Verrilli, MR1
Salanga, VD1
Kozachuk, WE1
Bennetts, M1

Other Studies

9 other studies available for dantrolene and Poisoning

ArticleYear
Dantrolene is not the answer to 2,4-dinitrophenol poisoning: more heated debate.
    BMJ case reports, 2018, Dec-19, Volume: 11, Issue:1

    Topics: 2,4-Dinitrophenol; Administration, Intravenous; Adult; Anti-Obesity Agents; Dantrolene; Fatal Outcom

2018
'Fatal 2,4-dinitrophenol poisoning... coming to a hospital near you'.
    Emergency medicine journal : EMJ, 2010, Volume: 27, Issue:8

    Topics: 2,4-Dinitrophenol; Adult; Calcium Gluconate; Dantrolene; Emergency Treatment; Fatal Outcome; Humans;

2010
Comment on "Pediatric fatality following ingestion of Dinitrophenol: postmortem identification of a 'dietary supplement'".
    Clinical toxicology (Philadelphia, Pa.), 2006, Volume: 44, Issue:3

    Topics: Adult; Child; Dantrolene; Dietary Supplements; Dinitrophenols; Fatal Outcome; Fever; Humans; Muscle

2006
Ecstasy overdose: a case study.
    Intensive & critical care nursing, 1995, Volume: 11, Issue:1

    Topics: Adult; Dantrolene; Emergency Service, Hospital; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine

1995
The management of acute poisoning.
    British journal of anaesthesia, 1993, Volume: 71, Issue:4

    Topics: Dantrolene; Fever; Humans; Myocardial Infarction; Poisoning; Unconsciousness

1993
Neuroleptic malignant-like syndrome: a complication of acute organophosphate poisoning.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1995, Volume: 42, Issue:11

    Topics: Atropine; Cholinesterase Reactivators; Cholinesterases; Dantrolene; Female; Humans; Middle Aged; Mio

1995
An unusual case of Ecstasy poisoning.
    Intensive care medicine, 1996, Volume: 22, Issue:7

    Topics: Adult; Creatine Kinase; Dantrolene; Humans; Male; Muscle Relaxants, Central; N-Methyl-3,4-methylened

1996
Ecstasy poisoning.
    Intensive & critical care nursing, 1997, Volume: 13, Issue:6

    Topics: Critical Care; Dantrolene; Designer Drugs; Hallucinogens; Humans; Muscle Relaxants, Central; N-Methy

1997
Phenelzine toxicity responsive to dantrolene.
    Neurology, 1987, Volume: 37, Issue:5

    Topics: Adult; Dantrolene; Humans; Male; Phenelzine; Poisoning

1987