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dantrolene and Pleural Effusion

dantrolene has been researched along with Pleural Effusion in 11 studies

Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.

Pleural Effusion: Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself.

Research Excerpts

ExcerptRelevanceReference
"To describe a new case of eosinophilic pleural effusion induced by dantrolene chronic administration."8.82Dantrolene and pleural effusion: case report and review of literature. ( Calmels, P; Fayolle-Minon, I; Gautheron, V; Lê-Quang, B; Valayer-Chaléat, E, 2004)
"Twelve years after the initiation of low-dose dantrolene therapy for chronic spasticity, a 35-year-old man developed a pleural effusion with pleural and peripheral eosinophilia."8.79Pleural effusion associated with chronic dantrolene administration. ( Bachtel, MD; Mahoney, JM, 1994)
" He had been treated for spastic paraplegia with dantrolene sodium for 28 months."7.71[Eosinophilic pleural effusion associated with dantrolene administration]. ( Asada, K; Chida, K; Inui, N; Kuwata, H; Matsuda, H; Miwa, S; Nakamura, H; Nakamura, Y; Nakano, H; Shirai, T; Suda, T; Suzuki, K; Yokomura, K, 2002)
"A patient developed pulmonary infiltration, pleural effusions and pericarditis three months after starting dantrolene sodium."7.67Pneumonitis, pleural effusion and pericarditis following treatment with dantrolene. ( Haas, LF; Miller, DH, 1984)
"A quadriplegic patient with severe spasticity, treated with dantrolene (400 mg daily) for 5 years, had dyspnea, orthopnea, hypoxia, and right-sided opacity of the chest on radiograph."5.31Eosinophilic pleural effusion due to dantrolene: resolution with steroid therapy. ( Felz, MW; Haviland-Foley, DJ, 2001)
"To describe a new case of eosinophilic pleural effusion induced by dantrolene chronic administration."4.82Dantrolene and pleural effusion: case report and review of literature. ( Calmels, P; Fayolle-Minon, I; Gautheron, V; Lê-Quang, B; Valayer-Chaléat, E, 2004)
"Twelve years after the initiation of low-dose dantrolene therapy for chronic spasticity, a 35-year-old man developed a pleural effusion with pleural and peripheral eosinophilia."4.79Pleural effusion associated with chronic dantrolene administration. ( Bachtel, MD; Mahoney, JM, 1994)
" He had been treated for spastic paraplegia with dantrolene sodium for 28 months."3.71[Eosinophilic pleural effusion associated with dantrolene administration]. ( Asada, K; Chida, K; Inui, N; Kuwata, H; Matsuda, H; Miwa, S; Nakamura, H; Nakamura, Y; Nakano, H; Shirai, T; Suda, T; Suzuki, K; Yokomura, K, 2002)
"A patient developed pulmonary infiltration, pleural effusions and pericarditis three months after starting dantrolene sodium."3.67Pneumonitis, pleural effusion and pericarditis following treatment with dantrolene. ( Haas, LF; Miller, DH, 1984)
"The pleural effusions are typically chronic and somewhat torpid, most often bilateral but may be unilateral."2.39[Drug-induced pleurisy]. ( Benard, A; Guenanen, H; Tillie-Leblond, I; Wallaert, B, 1996)
"A quadriplegic patient with severe spasticity, treated with dantrolene (400 mg daily) for 5 years, had dyspnea, orthopnea, hypoxia, and right-sided opacity of the chest on radiograph."1.31Eosinophilic pleural effusion due to dantrolene: resolution with steroid therapy. ( Felz, MW; Haviland-Foley, DJ, 2001)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's2 (18.18)18.2507
2000's4 (36.36)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alagha, K1
Tummino, C1
Sofalvi, T1
Chanez, P1
Krenke, R1
Light, RW1
Yokomura, K1
Chida, K1
Suda, T1
Miwa, S1
Nakano, H1
Kuwata, H1
Suzuki, K2
Matsuda, H1
Asada, K1
Nakamura, Y1
Inui, N1
Shirai, T1
Nakamura, H1
Lê-Quang, B1
Calmels, P1
Valayer-Chaléat, E1
Fayolle-Minon, I1
Gautheron, V1
Okada, M1
Nakagawa, E1
Masuyama, T1
Fujikawa, Y1
Komaki, H1
Sugai, K1
Sasaki, M1
Miller, DH1
Haas, LF1
Mahoney, JM1
Bachtel, MD1
Benard, A1
Guenanen, H1
Tillie-Leblond, I1
Wallaert, B1
Felz, MW1
Haviland-Foley, DJ1
Petusevsky, ML1
Faling, LJ1
Rocklin, RE1
Snider, GL1
Merliss, AD1
Moses, JM1
Dorman, SA1
Sahn, SA1

Reviews

6 reviews available for dantrolene and Pleural Effusion

ArticleYear
Iatrogenic eosinophilic pleural effusion.
    European respiratory review : an official journal of the European Respiratory Society, 2011, Volume: 20, Issue:120

    Topics: Adult; Benzodiazepines; Biopsy; Dantrolene; Eosinophilia; Humans; Iatrogenic Disease; Male; Middle A

2011
Dantrolene and pleural effusion: case report and review of literature.
    Spinal cord, 2004, Volume: 42, Issue:5

    Topics: Dantrolene; Female; Humans; Middle Aged; Muscle Relaxants, Central; Muscle, Skeletal; Nitrofurantoin

2004
[Pleural effusion associated with long-term dantrolene administration in three patients with severe motor and intellectual disabilities].
    No to hattatsu = Brain and development, 2006, Volume: 38, Issue:1

    Topics: Adult; Dantrolene; Diagnosis, Differential; Disabled Persons; Eosinophilia; Female; Humans; Intellec

2006
Pleural effusion associated with chronic dantrolene administration.
    The Annals of pharmacotherapy, 1994, Volume: 28, Issue:5

    Topics: Adult; Dantrolene; Eosinophilia; Humans; Male; Pleural Effusion; Time Factors

1994
[Drug-induced pleurisy].
    Revue des maladies respiratoires, 1996, Volume: 13, Issue:3

    Topics: Bromocriptine; Dantrolene; Dopamine Agonists; Ergotamines; Fibrosis; Humans; Muscle Relaxants, Centr

1996
Immunologic diseases of the pleura.
    Clinics in chest medicine, 1985, Volume: 6, Issue:1

    Topics: Adult; Aged; Bromocriptine; Cardiac Surgical Procedures; Collagen Diseases; Dantrolene; Female; Gran

1985

Other Studies

5 other studies available for dantrolene and Pleural Effusion

ArticleYear
Drug-induced eosinophilic pleural effusion.
    European respiratory review : an official journal of the European Respiratory Society, 2011, Volume: 20, Issue:122

    Topics: Benzodiazepines; Dantrolene; Eosinophilia; Humans; Iatrogenic Disease; Male; Muscle Relaxants, Centr

2011
[Eosinophilic pleural effusion associated with dantrolene administration].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2002, Volume: 40, Issue:6

    Topics: Adult; Dantrolene; Diagnosis, Differential; Eosinophilia; Humans; Male; Paraplegia; Pleural Effusion

2002
Pneumonitis, pleural effusion and pericarditis following treatment with dantrolene.
    Journal of neurology, neurosurgery, and psychiatry, 1984, Volume: 47, Issue:5

    Topics: Adult; Dantrolene; Female; Humans; Muscle Spasticity; Pericarditis; Pleural Effusion; Pneumonia; Rad

1984
Eosinophilic pleural effusion due to dantrolene: resolution with steroid therapy.
    Southern medical journal, 2001, Volume: 94, Issue:5

    Topics: Adult; Anti-Inflammatory Agents; Dantrolene; Drug Hypersensitivity; Eosinophilia; Humans; Male; Musc

2001
Pleuropericardial reaction to treatment with dantrolene.
    JAMA, 1979, Dec-21, Volume: 242, Issue:25

    Topics: Acute Disease; Adult; Chronic Disease; Dantrolene; Female; Humans; Male; Middle Aged; Muscle Spastic

1979