dantrolene has been researched along with Palsy in 5 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The mode of action of dantrolene sodium was studied in 11 multiple sclerosis patients with spastic paresis of the legs by measurements of changes in electromyographic and mechanomyographic proprioceptive reflex responses and in voluntary power." | 3.66 | Mode of action of dantrolene sodium in spasticity. ( Mai, J; Pedersen, E, 1979) |
| "In 25 patients with spasticity, pharmacokinetics and effects of dantrolene sodium were investigated after prolonged administration." | 1.26 | The effect of dantrolene sodium in relation to blood levels in spastic patients after prolonged administration. ( Agoston, S; Bakker, H; Kok, JJ; Meyler, WJ; Wesseling, H, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Oliven, A | 1 |
| Deal, EC | 1 |
| Kelsen, SG | 1 |
| Cherniack, NS | 1 |
| Meyler, WJ | 1 |
| Bakker, H | 1 |
| Kok, JJ | 1 |
| Agoston, S | 1 |
| Wesseling, H | 1 |
| Mai, J | 1 |
| Pedersen, E | 1 |
| Weiser, R | 1 |
| Terenty, T | 1 |
| Hudgson, P | 1 |
| Weightman, D | 1 |
| Ladd, HW | 1 |
| Gingras, G | 1 |
| Boucher, J | 1 |
| Kazdan, N | 1 |
| Keenan, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of EXOPULSE Mollii Suit on Spasticity and Muscular Oxygenation in Patients With Multiple Sclerosis.[NCT05912595] | 36 participants (Anticipated) | Interventional | 2023-05-18 | Recruiting | |||
| The Effects of EXOPULSE Mollii Suit on Motor Functions in Patients With Multiple Sclerosis (EXOSEP 2)[NCT05857280] | 36 participants (Anticipated) | Interventional | 2023-03-21 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for dantrolene and Palsy
| Article | Year |
|---|---|
Dantrolene sodium in the treatment of spasticity in chronic spinal cord disease.
Topics: Adult; Aged; Chronic Disease; Clinical Trials as Topic; Dantrolene; Double-Blind Method; Female; Hum | 1978 |
[Attenuating effect of a new pharmacological agent (Dantrolene sodium) on spasticity].
Topics: Adolescent; Adult; Child; Clinical Trials as Topic; Dantrolene; Evaluation Studies as Topic; Humans; | 1973 |
3 other studies available for dantrolene and Palsy
| Article | Year |
|---|---|
Respiratory response to partial paralysis in anesthetized dogs.
Topics: Anesthesia, General; Animals; Dantrolene; Diaphragm; Dogs; Electromyography; Gallamine Triethiodide; | 1984 |
The effect of dantrolene sodium in relation to blood levels in spastic patients after prolonged administration.
Topics: Adult; Aged; Brain Concussion; Dantrolene; Dose-Response Relationship, Drug; Female; Humans; Male; M | 1981 |
Mode of action of dantrolene sodium in spasticity.
Topics: Dantrolene; Drug Evaluation; Electromyography; Humans; Injections, Intravenous; Motor Neurons; Multi | 1979 |
Mode of action of dantrolene sodium in spasticity.
Topics: Dantrolene; Drug Evaluation; Electromyography; Humans; Injections, Intravenous; Motor Neurons; Multi | 1979 |
Mode of action of dantrolene sodium in spasticity.
Topics: Dantrolene; Drug Evaluation; Electromyography; Humans; Injections, Intravenous; Motor Neurons; Multi | 1979 |
Mode of action of dantrolene sodium in spasticity.
Topics: Dantrolene; Drug Evaluation; Electromyography; Humans; Injections, Intravenous; Motor Neurons; Multi | 1979 |