dantrolene has been researched along with Pain, Postoperative in 5 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
Pain, Postoperative: Pain during the period after surgery.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Malignant syndrome is a disease characterized by high fever, extrapyramidal syndrome and dysautonomia recognized during or at the time of stopping administration of antipsychotic medication and it is the most severe and lethal side effect of antipsychotic medication." | 5.30 | [A case of malignant syndrome triggered by the use of haloperidol and chrorpromazine]. ( Fujimoto, K; Konishi, K; Kubota, M; Ogawa, H, 1997) |
| "A single oral dose of dantrolene (100--150 mg) given at least 2 hr pre-operatively has been found to reduce significantly the strength of muscular fasciculations, the hyperkalaemia and the incidence of muscle pains following suxamethonium (from 56 to 4%) in a series of forty-eight patients compared with controls." | 5.04 | Dantrolene and suxamethonium. The effect of pre-operative dantrolene on the action of suxamethonium. ( Collier, CB, 1979) |
| " We conclude that dantrolene sodium, given in the dosage noted, is effective in reduction of analgesic requirements after tonsillectomy." | 2.66 | Oral dantrolene sodium for tonsillectomy pain: a double-blind study. ( Bellens, EE; Brown, AK; Lenis, A; Ruff, T; Salassa, JR; Seaman, SL, 1988) |
| "Malignant syndrome is a disease characterized by high fever, extrapyramidal syndrome and dysautonomia recognized during or at the time of stopping administration of antipsychotic medication and it is the most severe and lethal side effect of antipsychotic medication." | 1.30 | [A case of malignant syndrome triggered by the use of haloperidol and chrorpromazine]. ( Fujimoto, K; Konishi, K; Kubota, M; Ogawa, H, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Konishi, K | 1 |
| Fujimoto, K | 1 |
| Kubota, M | 1 |
| Ogawa, H | 1 |
| Collier, CB | 1 |
| Salassa, JR | 1 |
| Seaman, SL | 1 |
| Ruff, T | 1 |
| Lenis, A | 1 |
| Bellens, EE | 1 |
| Brown, AK | 1 |
| Wackym, PA | 1 |
| Abdul-Rasool, IH | 1 |
| Morganti, I | 1 |
4 trials available for dantrolene and Pain, Postoperative
| Article | Year |
|---|---|
Dantrolene and suxamethonium. The effect of pre-operative dantrolene on the action of suxamethonium.
Topics: Adult; Clinical Trials as Topic; Dantrolene; Drug Interactions; Fasciculation; Female; Humans; Hydan | 1979 |
Oral dantrolene sodium for tonsillectomy pain: a double-blind study.
Topics: Administration, Oral; Adolescent; Adult; Alkaline Phosphatase; Aspartate Aminotransferases; Child; C | 1988 |
Oral dantrolene sodium for tonsillectomy pain.
Topics: Clinical Trials as Topic; Dantrolene; Double-Blind Method; Humans; Pain, Postoperative; Random Alloc | 1988 |
[Evaluation of the mechanism determining the painful symptomatology after proctological interventions].
Topics: Adult; Aged; Anal Canal; Analgesics; Dantrolene; Double-Blind Method; Female; Hemorrhoids; Humans; M | 1988 |
1 other study available for dantrolene and Pain, Postoperative
| Article | Year |
|---|---|
[A case of malignant syndrome triggered by the use of haloperidol and chrorpromazine].
Topics: Adult; Antipsychotic Agents; Anxiety; Autonomic Nervous System Diseases; Basal Ganglia Diseases; Chl | 1997 |