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dantrolene and Otitis Media with Effusion

dantrolene has been researched along with Otitis Media with Effusion in 1 studies

Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.

Otitis Media with Effusion: Inflammation of the middle ear with a clear pale yellow-colored transudate.

Research Excerpts

ExcerptRelevanceReference
"The aims of our study were to assess whether the increased oxidative stress in experimental otitis media with effusion (OME) induced by histamine was reflected erythrocytes and middle ear effusion fluid by lipid peroxidation; to survey the alterations in antioxidant enzyme activities in experimental OME; and to determine the effect of dantrolene on this oxidative stress."7.73Effect of dantrolene on lipid peroxidation, lutathione and glutathione-dependent enzyme activities in experimental otitis media with effusion in guinea pigs. ( Aktan, B; Buyukokuroglu, ME; Elmastas, M; Taysi, S; Ucuncu, H, 2005)
"The aims of our study were to assess whether the increased oxidative stress in experimental otitis media with effusion (OME) induced by histamine was reflected erythrocytes and middle ear effusion fluid by lipid peroxidation; to survey the alterations in antioxidant enzyme activities in experimental OME; and to determine the effect of dantrolene on this oxidative stress."3.73Effect of dantrolene on lipid peroxidation, lutathione and glutathione-dependent enzyme activities in experimental otitis media with effusion in guinea pigs. ( Aktan, B; Buyukokuroglu, ME; Elmastas, M; Taysi, S; Ucuncu, H, 2005)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ucuncu, H1
Taysi, S1
Aktan, B1
Buyukokuroglu, ME1
Elmastas, M1

Other Studies

1 other study available for dantrolene and Otitis Media with Effusion

ArticleYear
Effect of dantrolene on lipid peroxidation, lutathione and glutathione-dependent enzyme activities in experimental otitis media with effusion in guinea pigs.
    Human & experimental toxicology, 2005, Volume: 24, Issue:11

    Topics: Animals; Dantrolene; Disease Models, Animal; Erythrocytes; Glutathione; Glutathione Peroxidase; Glut

2005