dantrolene has been researched along with Orphan Diseases in 2 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
Orphan Diseases: Rare diseases that have not been well studied.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Its main symptoms are: painful muscle spasms, diarrhea, alopecia and skeletal abnormalities." | 2.61 | Treatment of Satoyoshi syndrome: a systematic review. ( de Cabo, C; Solera, J; Solís-García Del Pozo, J, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Toyota, Y | 1 |
| Kondo, T | 1 |
| Shorin, D | 1 |
| Sumii, A | 1 |
| Kido, K | 1 |
| Watanabe, T | 1 |
| Otsuki, S | 1 |
| Kanzaki, R | 1 |
| Miyoshi, H | 1 |
| Yasuda, T | 1 |
| Horikawa, YT | 1 |
| Mukaida, K | 1 |
| Tsutsumi, YM | 1 |
| Solís-García Del Pozo, J | 1 |
| de Cabo, C | 1 |
| Solera, J | 1 |
1 review available for dantrolene and Orphan Diseases
| Article | Year |
|---|---|
Treatment of Satoyoshi syndrome: a systematic review.
Topics: Adrenal Cortex Hormones; Alopecia; Animals; Anticonvulsants; Bone and Bones; Dantrolene; Diarrhea; F | 2019 |
1 other study available for dantrolene and Orphan Diseases
| Article | Year |
|---|---|
Rapid Dantrolene Administration with Body Temperature Monitoring Is Associated with Decreased Mortality in Japanese Malignant Hyperthermia Events.
Topics: Body Temperature; Dantrolene; East Asian People; Humans; Malignant Hyperthermia; Rare Diseases; Retr | 2023 |