dantrolene has been researched along with Obesity in 3 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, a fatal malignant hyperthermia-like syndrome (MHLS) with rhabdomyolysis associated with new-onset diabetes mellitus and HHNS in adolescents has been described." | 1.33 | Approach to management of malignant hyperthermia-like syndrome in pediatric diabetes mellitus. ( Backeljauw, PF; Crimmins, NA; Kilbane, BJ; Mehta, S; Shanley, TP, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kilbane, BJ | 1 |
| Mehta, S | 1 |
| Backeljauw, PF | 1 |
| Shanley, TP | 1 |
| Crimmins, NA | 1 |
| Fürnsinn, C | 1 |
| Noe, C | 1 |
| Herdlicka, R | 1 |
| Roden, M | 1 |
| Nowotny, P | 1 |
| Leighton, B | 1 |
| Waldhäusl, W | 1 |
| Black, MA | 1 |
| Fournier, LA | 1 |
| Heick, HM | 1 |
| Bégin-Heick, N | 1 |
3 other studies available for dantrolene and Obesity
| Article | Year |
|---|---|
Approach to management of malignant hyperthermia-like syndrome in pediatric diabetes mellitus.
Topics: Adolescent; Black or African American; Butyryl-CoA Dehydrogenase; Child; Dantrolene; Diabetes Mellit | 2006 |
More marked stimulation by lithium than insulin of the glycogenic pathway in rat skeletal muscle.
Topics: Androstadienes; Animals; Biological Transport; Cytochalasin B; Dantrolene; Deoxyglucose; Glucose; Gl | 1997 |
Different insulin-secretory responses to calcium-channel blockers in islets of lean and obese (ob/ob) mice.
Topics: Animals; Colforsin; Dantrolene; Glucose; Insulin; Insulin Secretion; Ion Channels; Islets of Langerh | 1988 |