dantrolene has been researched along with Neurodegenerative Diseases in 2 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
Neurodegenerative Diseases: Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, L | 1 |
| Wei, H | 1 |
| Drake, TM | 1 |
1 review available for dantrolene and Neurodegenerative Diseases
| Article | Year |
|---|---|
Ryanodine Receptors: A Potential Treatment Target in Various Neurodegenerative Disease.
Topics: Animals; Brain; Calcium Channel Blockers; Calcium Signaling; Dantrolene; Humans; Neurodegenerative D | 2021 |
1 other study available for dantrolene and Neurodegenerative Diseases
| Article | Year |
|---|---|
Unfolding the promise of translational targeting in neurodegenerative disease.
Topics: Activating Transcription Factor 6; Aging; Animals; Apoptosis; Cellular Microenvironment; Dantrolene; | 2015 |