Page last updated: 2024-10-25

dantrolene and Neointima

dantrolene has been researched along with Neointima in 1 studies

Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.

Neointima: The new and thickened layer of scar tissue that forms on a PROSTHESIS, or as a result of vessel injury especially following ANGIOPLASTY or stent placement.

Research Excerpts

ExcerptRelevanceReference
"Dantrolene is a ryanodine receptor blocker that is used clinically for treatment of malignant hyperthermia."5.72Dantrolene reduces platelet-derived growth factor (PDGF)-induced vascular smooth muscle cell proliferation and neointimal formation following vascular injury in mice. ( Akase, H; Inamitsu, M; Kobayashi, S; Mikawa, M; Nakamura, Y; Oda, T; Okamura, T; Sakai, C; Suetomi, T; Tominaga, N; Uchida, T; Yamamoto, T; Yano, M, 2022)
"Dantrolene is a ryanodine receptor blocker that is used clinically for treatment of malignant hyperthermia."1.72Dantrolene reduces platelet-derived growth factor (PDGF)-induced vascular smooth muscle cell proliferation and neointimal formation following vascular injury in mice. ( Akase, H; Inamitsu, M; Kobayashi, S; Mikawa, M; Nakamura, Y; Oda, T; Okamura, T; Sakai, C; Suetomi, T; Tominaga, N; Uchida, T; Yamamoto, T; Yano, M, 2022)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Sakai, C1
Mikawa, M1
Yamamoto, T1
Uchida, T1
Nakamura, Y1
Akase, H1
Suetomi, T1
Tominaga, N1
Inamitsu, M1
Oda, T1
Okamura, T1
Kobayashi, S1
Yano, M1

Other Studies

1 other study available for dantrolene and Neointima

ArticleYear
Dantrolene reduces platelet-derived growth factor (PDGF)-induced vascular smooth muscle cell proliferation and neointimal formation following vascular injury in mice.
    Biochemical and biophysical research communications, 2022, 10-01, Volume: 623

    Topics: Animals; Cell Movement; Cell Proliferation; Cells, Cultured; Dantrolene; Disease Models, Animal; Mic

2022