Page last updated: 2024-10-25

dantrolene and Necrosis

dantrolene has been researched along with Necrosis in 3 studies

Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Furuta, Y1
Pena-Ramos, O1
Li, Z1
Chiao, L1
Zhou, Z1
Plank, C1
Hofmann, P1
Gruber, M1
Bollwein, G1
Graf, BM1
Zink, W1
Metterlein, T1
Yang, YT1
Whiteman, M1
Gieseg, SP1

Other Studies

3 other studies available for dantrolene and Necrosis

ArticleYear
Calcium ions trigger the exposure of phosphatidylserine on the surface of necrotic cells.
    PLoS genetics, 2021, Volume: 17, Issue:2

    Topics: Animals; Animals, Genetically Modified; Apoptosis; Caenorhabditis elegans; Caenorhabditis elegans Pr

2021
Modification of Bupivacaine-Induced Myotoxicity with Dantrolene and Caffeine In Vitro.
    Anesthesia and analgesia, 2016, Volume: 122, Issue:2

    Topics: Anesthetics, Local; Animals; Annexins; Bupivacaine; Caffeine; Central Nervous System Stimulants; Dan

2016
HOCl causes necrotic cell death in human monocyte derived macrophages through calcium dependent calpain activation.
    Biochimica et biophysica acta, 2012, Volume: 1823, Issue:2

    Topics: Calcimycin; Calcium; Calcium Channel Blockers; Calcium Ionophores; Calpain; Caspase 3; Cyclosporine;

2012