dantrolene has been researched along with Myotonia in 4 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
Myotonia: Prolonged failure of muscle relaxation after contraction. This may occur after voluntary contractions, muscle percussion, or electrical stimulation of the muscle. Myotonia is a characteristic feature of MYOTONIC DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pseudo-myotonia is the most important clinical feature." | 1.29 | Ca2+ homeostasis in Brody's disease. A study in skeletal muscle and cultured muscle cells and the effects of dantrolene an verapamil. ( Benders, AA; Bindels, RJ; Busch, HF; Jongen, PJ; Oosterhof, A; Smit, LM; Veerkamp, JH; Wevers, RA, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ritter, DM | 1 |
| Tian, C | 1 |
| Broomall, E | 1 |
| Sakai, T | 1 |
| Hosokawa, S | 1 |
| Shibasaki, H | 1 |
| Goto, I | 1 |
| Kuroiwa, Y | 1 |
| Sonoda, H | 1 |
| Murai, Y | 1 |
| Benders, AA | 1 |
| Veerkamp, JH | 1 |
| Oosterhof, A | 1 |
| Jongen, PJ | 1 |
| Bindels, RJ | 1 |
| Smit, LM | 1 |
| Busch, HF | 1 |
| Wevers, RA | 1 |
| Eberstein, A | 1 |
| Goodgold, J | 1 |
4 other studies available for dantrolene and Myotonia
| Article | Year |
|---|---|
Treatment of SCN4A-induced myotonic crisis.
Topics: Dantrolene; Diazepam; Humans; Male; Muscle Relaxants, Central; Myotonia; NAV1.4 Voltage-Gated Sodium | 2021 |
Syndrome of continuous muscle-fiber activity: increased CSF GABA and effect of dantrolene.
Topics: Adolescent; Dantrolene; Electromyography; Female; gamma-Aminobutyric Acid; H-Reflex; Humans; Myotoni | 1983 |
Ca2+ homeostasis in Brody's disease. A study in skeletal muscle and cultured muscle cells and the effects of dantrolene an verapamil.
Topics: Acetylcholine; Adolescent; Adult; Calcium; Calcium-Transporting ATPases; Cells, Cultured; Child; Dan | 1994 |
Relief of myotonia by dantrolene in experimental myotonia.
Topics: Animals; Dantrolene; Disease Models, Animal; Hydantoins; Male; Muscle Contraction; Muscle Relaxation | 1978 |