Page last updated: 2024-10-25

dantrolene and Muscular Dystrophy

dantrolene has been researched along with Muscular Dystrophy in 10 studies

Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.

Research Excerpts

ExcerptRelevanceReference
"To present a case of rhabdomyolysis which developed in a child with a known history of Duchenne's muscular dystrophy, following an anesthetic which included sevoflurane."3.70Rhabdomyolysis in association with Duchenne's muscular dystrophy. ( Nakajima, Y; Obata, R; Sato, S; Suzuki, A; Yasumi, Y, 1999)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19905 (50.00)18.7374
1990's3 (30.00)18.2507
2000's2 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shukry, M1
Guruli, ZV1
Ramadhyani, U1
Hattori, H1
Nagata, E1
Oya, Y1
Takahashi, T1
Aoki, M1
Ito, D1
Suzuki, N1
Willner, J1
Brownell, AK1
Paasuke, RT1
Elash, A1
Fowlow, SB1
Seagram, CG1
Diewold, RJ1
Friesen, C1
Kelfer, HM1
Singer, WD1
Reynolds, RN1
Fletcher, R1
Blennow, G1
Olsson, AK1
Ranklev, E1
Törnebrandt, K1
Benders, AA1
Wevers, RA1
Veerkamp, JH1
Obata, R1
Yasumi, Y1
Suzuki, A1
Nakajima, Y1
Sato, S1
Takamori, M1
Tsujihata, M1
Mori, M1
Hazama, R1
Ide, Y1
Bertorini, TE1
Palmieri, GM1
Griffin, J1
Igarashi, M1
Hinton, A1
Karas, JG1

Reviews

1 review available for dantrolene and Muscular Dystrophy

ArticleYear
Malignant hyperthermia.
    Pediatric annals, 1984, Volume: 13, Issue:2

    Topics: Anesthesia, General; Anesthesia, Local; Dantrolene; Disease Susceptibility; Female; Humans; Male; Ma

1984

Trials

1 trial available for dantrolene and Muscular Dystrophy

ArticleYear
Effect of dantrolene in Duchenne muscular dystrophy.
    Muscle & nerve, 1991, Volume: 14, Issue:6

    Topics: Adolescent; Child; Creatine Kinase; Dantrolene; Humans; Muscles; Muscular Dystrophies

1991

Other Studies

8 other studies available for dantrolene and Muscular Dystrophy

ArticleYear
Suspected malignant hyperthermia in a child with laminin alpha2 (merosin) deficiency in the absence of a triggering agent.
    Paediatric anaesthesia, 2006, Volume: 16, Issue:4

    Topics: Anesthesia, Intravenous; Child; Dantrolene; Dexmedetomidine; Humans; Laminin; Male; Malignant Hypert

2006
A novel compound heterozygous dysferlin mutation in Miyoshi myopathy siblings responding to dantrolene.
    European journal of neurology, 2007, Volume: 14, Issue:11

    Topics: Adolescent; Asian People; Dantrolene; Dysferlin; Female; Heterozygote; Humans; Male; Membrane Protei

2007
Malignant hyperthermia in Duchenne muscular dystrophy.
    Anesthesiology, 1983, Volume: 58, Issue:2

    Topics: Biopsy; Child, Preschool; Creatine Kinase; Dantrolene; Humans; Male; Malignant Hyperthermia; Muscles

1983
Malignant hyperthermia in a child with Duchenne muscular dystrophy.
    Pediatrics, 1983, Volume: 71, Issue:1

    Topics: Child, Preschool; Dantrolene; Humans; Male; Malignant Hyperthermia; Muscular Dystrophies; Preanesthe

1983
Malignant hyperthermia in a myopathic child. Prolonged postoperative course requiring dantrolene.
    Acta anaesthesiologica Scandinavica, 1982, Volume: 26, Issue:5

    Topics: Dantrolene; Humans; Infant; Malignant Hyperthermia; Muscular Dystrophies; Postoperative Complication

1982
Ion transport in human skeletal muscle cells: disturbances in myotonic dystrophy and Brody's disease.
    Acta physiologica Scandinavica, 1996, Volume: 156, Issue:3

    Topics: Acetylcholine; Adolescent; Adult; Biological Transport, Active; Calcium; Calcium Channel Blockers; C

1996
Rhabdomyolysis in association with Duchenne's muscular dystrophy.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1999, Volume: 46, Issue:6

    Topics: Acute Disease; Anesthetics, Inhalation; Child; Dantrolene; Humans; Male; Methyl Ethers; Muscle Relax

1999
[Contraction-relaxation properties of experimental denervated and immobilized muscle: comparison with dystrophic muscle (author's transl)].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1978, Mar-10, Volume: 67, Issue:3

    Topics: Action Potentials; Animals; Caffeine; Dantrolene; Humans; Immobilization; In Vitro Techniques; Isopr

1978