dantrolene has been researched along with Muscle Cramp in 6 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
Muscle Cramp: A sustained and usually painful contraction of muscle fibers. This may occur as an isolated phenomenon or as a manifestation of an underlying disease process (e.g., UREMIA; HYPOTHYROIDISM; MOTOR NEURON DISEASE; etc.). (From Adams et al., Principles of Neurology, 6th ed, p1398)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seventy-seven patients with muscle spasticity secondary to central nervous system pathology were treated with dantrolene sodium for periods of up to two years." | 9.04 | Dantrolene sodium: long-term effects in patients with muscle spasticity. ( Joynt, RL, 1976) |
| "Seventy-seven patients with muscle spasticity secondary to central nervous system pathology were treated with dantrolene sodium for periods of up to two years." | 5.04 | Dantrolene sodium: long-term effects in patients with muscle spasticity. ( Joynt, RL, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakamura, K | 1 |
| Yoshizaki, A | 1 |
| Saigusa, R | 1 |
| Taniguchi, T | 1 |
| Asano, Y | 1 |
| Sato, S | 1 |
| Butala, BN | 1 |
| Kang, A | 1 |
| Guron, J | 1 |
| Brandom, BW | 1 |
| Lee, KK | 1 |
| Omiya, Y | 1 |
| Yuzurihara, M | 1 |
| Kase, Y | 1 |
| Kobayashi, H | 1 |
| Myers, A | 1 |
| Takeuchi, A | 1 |
| Kajihara, A | 1 |
| Kobayashi, S | 1 |
| Kobayashi, K | 1 |
| Joynt, RL | 1 |
1 trial available for dantrolene and Muscle Cramp
| Article | Year |
|---|---|
Dantrolene sodium: long-term effects in patients with muscle spasticity.
Topics: Adolescent; Adult; Child; Clinical Trials as Topic; Dantrolene; Drug Evaluation; Female; Humans; Hyd | 1976 |
5 other studies available for dantrolene and Muscle Cramp
| Article | Year |
|---|---|
The efficacy of dantrolene sodium for muscle cramps in patients with localized scleroderma.
Topics: Adult; Dantrolene; Female; Humans; Male; Middle Aged; Muscle Cramp; Muscle Relaxants, Central; Scler | 2016 |
Long term oral Dantrolene Improved Muscular Symptoms in a Malignant Hyperthermia Susceptible Individual.
Topics: Adult; Chronic Pain; Creatine Kinase; Dantrolene; Female; Humans; Malignant Hyperthermia; Muscle Cra | 2016 |
Antispasmodic effect of shakuyakukanzoto extract on experimental muscle cramps in vivo: role of the active constituents of Glycyrrhizae radix.
Topics: Animals; Animals, Outbred Strains; Chalcone; Chalcones; Coumarins; Dantrolene; Disease Models, Anima | 2013 |
Dantrolene, pelvic neoplasm, and muscle spasms: report of a case.
Topics: Aged; Dantrolene; Humans; Hydantoins; Leg; Male; Muscle Cramp; Pelvic Neoplasms | 1977 |
[Endocrine abnormalities in systemic muscle cramp].
Topics: Adult; Dantrolene; Female; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Muscle Cramp | 1978 |