dantrolene has been researched along with Multiple Organ Failure in 4 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
Multiple Organ Failure: A progressive condition usually characterized by combined failure of several organs such as the lungs, liver, kidney, along with some clotting mechanisms, usually postinjury or postoperative.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Following initial improvement, she developed delayed rhabdomyolysis then haloperidol-induced neuroleptic malignant syndrome, which was treated with a total of 50 mg." | 3.78 | Ecstacy-induced delayed rhabdomyolysis and neuroleptic malignant syndrome in a patient with a novel variant in the ryanodine receptor type 1 gene. ( Hawryluck, LA; Kraeva, N; Riazi, S; Russell, T; Steel, AC, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wei, H | 1 |
| Liang, G | 1 |
| Vera, RM | 1 |
| Russell, T | 1 |
| Riazi, S | 1 |
| Kraeva, N | 1 |
| Steel, AC | 1 |
| Hawryluck, LA | 1 |
| Hamanaka, S | 1 |
| Hata, T | 1 |
| Tsushima, Y | 1 |
| Matsumoto, M | 1 |
| Fujiwara, K | 1 |
| Furukawa, H | 1 |
| Kuroki, K | 1 |
| Masuda, Z | 1 |
| Hall, AP | 1 |
1 review available for dantrolene and Multiple Organ Failure
| Article | Year |
|---|---|
Dantrolene repurposed to treat sepsis or septic shock and COVID-19 patients.
Topics: Calcium; Calcium Channel Blockers; COVID-19; COVID-19 Drug Treatment; Dantrolene; Drug Repositioning | 2021 |
3 other studies available for dantrolene and Multiple Organ Failure
| Article | Year |
|---|---|
Ecstacy-induced delayed rhabdomyolysis and neuroleptic malignant syndrome in a patient with a novel variant in the ryanodine receptor type 1 gene.
Topics: Anesthetics, Inhalation; Antipsychotic Agents; Body Temperature; Caffeine; Central Nervous System St | 2012 |
[A case of an adult patient of tetralogy of Fallot having malignant hyperthermia during surgery].
Topics: Adult; Cardiopulmonary Bypass; Dantrolene; Humans; Hypertension, Malignant; Intraoperative Complicat | 1997 |
Ecstasy: creatinine kinase.
Topics: 3,4-Methylenedioxyamphetamine; Creatine Kinase; Dantrolene; Designer Drugs; Fever; Humans; Multiple | 1997 |