dantrolene has been researched along with Melanoma in 2 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To report the case of a 58-year-old male with melanoma who developed aldesleukin-induced rigors and was successfully treated with intravenous dantrolene sodium 20 mg and provide a review of the literature discussing other agents that have been used to treat drug-induced rigors." | 7.78 | Dantrolene sodium for the treatment of aldesleukin-induced rigors in a melanoma patient. ( Azari, LM; Jones, TS; Sachdev, JC; Sheehan, VS, 2012) |
| "To report the case of a 58-year-old male with melanoma who developed aldesleukin-induced rigors and was successfully treated with intravenous dantrolene sodium 20 mg and provide a review of the literature discussing other agents that have been used to treat drug-induced rigors." | 3.78 | Dantrolene sodium for the treatment of aldesleukin-induced rigors in a melanoma patient. ( Azari, LM; Jones, TS; Sachdev, JC; Sheehan, VS, 2012) |
| "Cutaneous melanoma is the most serious type of skin cancer, so new cytotoxic weapons against novel targets in melanoma are of great interest." | 1.48 | Anticancer Activity of Euplotin C, Isolated from the Marine Ciliate ( Alcantara Barata, G; Carpi, S; Di Giuseppe, G; Fogli, S; Frontini, FP; Guella, G; Nieri, P; Poli, G; Polini, B; Romanini, A; Tuccinardi, T, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carpi, S | 1 |
| Polini, B | 1 |
| Poli, G | 1 |
| Alcantara Barata, G | 1 |
| Fogli, S | 1 |
| Romanini, A | 1 |
| Tuccinardi, T | 1 |
| Guella, G | 1 |
| Frontini, FP | 1 |
| Nieri, P | 1 |
| Di Giuseppe, G | 1 |
| Azari, LM | 1 |
| Sheehan, VS | 1 |
| Sachdev, JC | 1 |
| Jones, TS | 1 |
2 other studies available for dantrolene and Melanoma
| Article | Year |
|---|---|
Anticancer Activity of Euplotin C, Isolated from the Marine Ciliate
Topics: Apoptosis; Aquatic Organisms; Calcium Channel Agonists; Cell Line, Tumor; Dantrolene; Drug Evaluatio | 2018 |
Dantrolene sodium for the treatment of aldesleukin-induced rigors in a melanoma patient.
Topics: Antineoplastic Agents; Chills; Dantrolene; Humans; Interleukin-2; Male; Melanoma; Middle Aged; Muscl | 2012 |