dantrolene has been researched along with Liver Neoplasms in 4 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
Liver Neoplasms: Tumors or cancer of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A patient is reported who was on prolonged treatment with dantrolene for spastic paraplegia; he developed a malignant lymphoma which led to his death." | 3.66 | Dantrolene and lymphocytic lymphoma. ( Tucker, JS; Wan, HH, 1980) |
| "We report a case of malignant hyperthermialike syndrome in a living-donor liver transplant recipient with no familial history of malignant hyperthermia or exposure to known triggering drugs." | 1.39 | A malignant hyperthermialike episode in a liver transplant recipient. ( Fukuda, K; Segawa, H; Tsujikawa, H, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zakaria, S | 1 |
| Ansary, A | 1 |
| Abdel-Hamid, NM | 1 |
| El-Shishtawy, MM | 1 |
| Tsujikawa, H | 1 |
| Segawa, H | 1 |
| Fukuda, K | 1 |
| Wan, HH | 1 |
| Tucker, JS | 1 |
| Kim, JA | 1 |
| Kang, YS | 1 |
| Lee, SH | 1 |
| Lee, EH | 1 |
| Yoo, BH | 1 |
| Lee, YS | 1 |
4 other studies available for dantrolene and Liver Neoplasms
| Article | Year |
|---|---|
Dantrolene Potentiates the Antineoplastic Effect of Sorafenib in Hepatocellular Carcinoma via Targeting Ca
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Dan | 2021 |
A malignant hyperthermialike episode in a liver transplant recipient.
Topics: Carcinoma, Hepatocellular; Comorbidity; Dantrolene; Hepatitis C; Humans; Intraoperative Complication | 2013 |
Dantrolene and lymphocytic lymphoma.
Topics: Dantrolene; Humans; Liver Neoplasms; Lymphoma, Non-Hodgkin; Male; Middle Aged; Muscle Spasticity; Pa | 1980 |
Glibenclamide induces apoptosis through inhibition of cystic fibrosis transmembrane conductance regulator (CFTR) Cl(-) channels and intracellular Ca(2+) release in HepG2 human hepatoblastoma cells.
Topics: Apoptosis; Caco-2 Cells; Calcium; Chlorides; Cystic Fibrosis Transmembrane Conductance Regulator; Da | 1999 |