Page last updated: 2024-10-25

dantrolene and Liver Dysfunction

dantrolene has been researched along with Liver Dysfunction in 2 studies

Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.

Research Excerpts

ExcerptRelevanceReference
"Mean dantrolene dose was 582 mg/d in fatal cases and 263 mg/d in the nonfatal group."1.28Dantrolene sodium and hepatic injury. ( Chan, CH, 1990)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chan, CH1
James, OF1

Reviews

1 review available for dantrolene and Liver Dysfunction

ArticleYear
Drugs and the ageing liver.
    Journal of hepatology, 1985, Volume: 1, Issue:4

    Topics: Aged; Aging; Biotransformation; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Syst

1985

Other Studies

1 other study available for dantrolene and Liver Dysfunction

ArticleYear
Dantrolene sodium and hepatic injury.
    Neurology, 1990, Volume: 40, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biopsy; Central Nervous System Diseases; Chemical and Dr

1990