dantrolene has been researched along with Liver Dysfunction in 2 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mean dantrolene dose was 582 mg/d in fatal cases and 263 mg/d in the nonfatal group." | 1.28 | Dantrolene sodium and hepatic injury. ( Chan, CH, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chan, CH | 1 |
| James, OF | 1 |
1 review available for dantrolene and Liver Dysfunction
| Article | Year |
|---|---|
Drugs and the ageing liver.
Topics: Aged; Aging; Biotransformation; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Syst | 1985 |
1 other study available for dantrolene and Liver Dysfunction
| Article | Year |
|---|---|
Dantrolene sodium and hepatic injury.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biopsy; Central Nervous System Diseases; Chemical and Dr | 1990 |