dantrolene has been researched along with Ischemia in 5 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study we used two calcium antagonists which have two different modes of action, nimodipine and dantrolene, to prevent NMDA-induced retinal ischemia in guinea pigs." | 3.72 | Calcium antagonists in N-methyl d-aspartate-induced retinal injury. ( Altuntaş, I; Kaya, M; Ozdemir, T; Tunç, M, 2003) |
| "In this report, we describe a case of malignant hyperthermia, its clinical course, and the measures taken to successfully treat it and preserve the function of a kidney allograft." | 1.29 | Successful treatment of intraoperative malignant hyperthermia during renal transplantation. ( Brennan, DC; Flye, MW; Goss, JA; Howard, TK; McClure, S; Miller, BT; Shenoy, S, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kaya, M | 1 |
| Tunç, M | 1 |
| Ozdemir, T | 1 |
| Altuntaş, I | 1 |
| Li, F | 1 |
| Hayashi, T | 1 |
| Jin, G | 1 |
| Deguchi, K | 1 |
| Nagotani, S | 1 |
| Nagano, I | 1 |
| Shoji, M | 1 |
| Chan, PH | 1 |
| Abe, K | 1 |
| Klenerman, L | 1 |
| Lowe, NM | 1 |
| Miller, I | 1 |
| Fryer, PR | 1 |
| Green, CJ | 1 |
| Jackson, MJ | 1 |
| Goss, JA | 1 |
| Brennan, DC | 1 |
| Miller, BT | 1 |
| Shenoy, S | 1 |
| McClure, S | 1 |
| Howard, TK | 1 |
| Flye, MW | 1 |
| Wevers, RA | 1 |
| Poels, PJ | 1 |
| Joosten, EM | 1 |
| Steenbergen, GG | 1 |
| Benders, AA | 1 |
| Veerkamp, JH | 1 |
5 other studies available for dantrolene and Ischemia
| Article | Year |
|---|---|
Calcium antagonists in N-methyl d-aspartate-induced retinal injury.
Topics: Animals; Calcium Channel Blockers; Cell Count; Dantrolene; Drug Therapy, Combination; Excitatory Ami | 2003 |
The protective effect of dantrolene on ischemic neuronal cell death is associated with reduced expression of endoplasmic reticulum stress markers.
Topics: Activating Transcription Factor 4; Analysis of Variance; Animals; Blotting, Western; CCAAT-Enhancer- | 2005 |
Dantrolene sodium protects against experimental ischemia and reperfusion damage to skeletal muscle.
Topics: Animals; Cations; Dantrolene; Glutathione; In Vitro Techniques; Infusions, Intravenous; Ischemia; Mi | 1995 |
Successful treatment of intraoperative malignant hyperthermia during renal transplantation.
Topics: Adult; Anesthesia, General; Dantrolene; Humans; Intraoperative Complications; Ischemia; Kidney; Kidn | 1996 |
Ischaemic forearm testing in a patient with Ca(2+)-ATPase deficiency.
Topics: Adult; Arm; Calcium-Transporting ATPases; Dantrolene; Exercise; Humans; Ischemia; Lactates; Lactic A | 1992 |