dantrolene has been researched along with Intellectual Disability in 5 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
Intellectual Disability: Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)
| Excerpt | Relevance | Reference |
|---|---|---|
| " NMS occurs most often during the first week of treatment or after increasing the dosage of the neuroleptic medication." | 1.43 | [Case report: Neuroleptic malignant syndrome and diagnostic difficulties]. ( Khouri, C; Logerot, S; Mallaret, M; Planès, S; Villier, C, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khouri, C | 1 |
| Planès, S | 1 |
| Logerot, S | 1 |
| Villier, C | 1 |
| Mallaret, M | 1 |
| Okada, M | 1 |
| Nakagawa, E | 1 |
| Masuyama, T | 1 |
| Fujikawa, Y | 1 |
| Komaki, H | 1 |
| Sugai, K | 1 |
| Sasaki, M | 1 |
| Nisijima, K | 1 |
| Matoba, M | 1 |
| Ishiguro, T | 1 |
| García-Castro, JM | 1 |
| Sczesni, B | 1 |
| Becker, H | 1 |
| Schröder, J | 1 |
| Bittkau, S | 1 |
| von Baumgarten, F | 1 |
| Truong, DD | 1 |
| Przuntek, H | 1 |
1 review available for dantrolene and Intellectual Disability
| Article | Year |
|---|---|
[Pleural effusion associated with long-term dantrolene administration in three patients with severe motor and intellectual disabilities].
Topics: Adult; Dantrolene; Diagnosis, Differential; Disabled Persons; Eosinophilia; Female; Humans; Intellec | 2006 |
1 trial available for dantrolene and Intellectual Disability
| Article | Year |
|---|---|
Dantrolene sodium: an effective therapeutic agent for the treatment of spasticity in children.
Topics: Capsules; Child; Child, Preschool; Clinical Trials as Topic; Dantrolene; Drug Evaluation; Humans; Hy | 1977 |
3 other studies available for dantrolene and Intellectual Disability
| Article | Year |
|---|---|
[Case report: Neuroleptic malignant syndrome and diagnostic difficulties].
Topics: Antipsychotic Agents; Dantrolene; Female; Humans; Intellectual Disability; Middle Aged; Muscle Relax | 2016 |
Single photon emission computed tomography with 123I-IMP in three cases of the neuroleptic malignant syndrome.
Topics: Adult; Amphetamines; Antipsychotic Agents; Basal Ganglia; Brain; Dantrolene; Dose-Response Relations | 1994 |
[Diagnostic and therapeutic aspects of neuroleptic malignant syndrome based on 12 cases].
Topics: Adult; Amantadine; Antipsychotic Agents; Bromocriptine; Dantrolene; Depressive Disorder; Diazepam; D | 1991 |