Page last updated: 2024-10-25

dantrolene and Inflammation

dantrolene has been researched along with Inflammation in 1 studies

Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
"Paclitaxel treatment resulted in a peripheral neuropathy that affected the two hindpaws."1.35Different antinociceptive effects of botulinum toxin type A in inflammatory and peripheral polyneuropathic rat models. ( Auguet, M; Chabrier, PE; Favre-Guilmard, C, 2009)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Favre-Guilmard, C1
Auguet, M1
Chabrier, PE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Botulinum Toxin A for the Treatment of Chemotherapy Induced Peripheral Neuropathy[NCT03571334]Phase 240 participants (Anticipated)Interventional2020-07-08Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

1 other study available for dantrolene and Inflammation

ArticleYear
Different antinociceptive effects of botulinum toxin type A in inflammatory and peripheral polyneuropathic rat models.
    European journal of pharmacology, 2009, Sep-01, Volume: 617, Issue:1-3

    Topics: Analgesics; Animals; Botulinum Toxins, Type A; Carrageenan; Dantrolene; Disease Models, Animal; Edem

2009