dantrolene has been researched along with Hypoxia-Ischemia, Brain in 2 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
Hypoxia-Ischemia, Brain: A disorder characterized by a reduction of oxygen in the blood combined with reduced blood flow (ISCHEMIA) to the brain from a localized obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ISCHEMIC ATTACK, TRANSIENT; BRAIN INFARCTION; BRAIN EDEMA; COMA; and other conditions.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ovcjak, A | 1 |
| Xiao, A | 1 |
| Kim, JS | 1 |
| Xu, B | 1 |
| Szeto, V | 1 |
| Turlova, E | 1 |
| Abussaud, A | 1 |
| Chen, NH | 1 |
| Miller, SP | 1 |
| Sun, HS | 1 |
| Feng, ZP | 1 |
| Gwak, M | 1 |
| Park, P | 1 |
| Kim, K | 1 |
| Lim, K | 1 |
| Jeong, S | 1 |
| Baek, C | 1 |
| Lee, J | 1 |
2 other studies available for dantrolene and Hypoxia-Ischemia, Brain
| Article | Year |
|---|---|
Ryanodine receptor inhibitor dantrolene reduces hypoxic-ischemic brain injury in neonatal mice.
Topics: Animals; Animals, Newborn; Brain Injuries; Calcium; Calcium Channel Blockers; Dantrolene; Homeostasi | 2022 |
The effects of dantrolene on hypoxic-ischemic injury in the neonatal rat brain.
Topics: Animals; Animals, Newborn; Apoptosis; Aspartic Acid; Brain; Carotid Artery, Common; Creatine; Dantro | 2008 |