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dantrolene and Hyperthyroidism

dantrolene has been researched along with Hyperthyroidism in 4 studies

Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.

Hyperthyroidism: Hypersecretion of THYROID HORMONES from the THYROID GLAND. Elevated levels of thyroid hormones increase BASAL METABOLIC RATE.

Research Excerpts

ExcerptRelevanceReference
"The effect of altering external calcium concentration [Ca2+]o on the negative inotropic action of dantrolene was tested in Langendorff-perfused hearts from euthyroid and hyperthyroid rats."7.68The effect of external calcium concentration on the negative inotropic action of dantrolene in isolated hyperthyroid and euthyroid heart. ( Butkow, N; Wheatley, AM, 1991)
"1 The effects of dantrolene on twitch and tetanic force development were determined in soleus and gastrocnemius muscle of euthyroid, hypothyroid, and hyperthyroid rats."7.67Effects of dantrolene on force development in slow- and fast-twitch muscle of euthyroid, hypothyroid, and hyperthyroid rats. ( Everts, ME; van Hardeveld, C, 1987)
"The effect of altering external calcium concentration [Ca2+]o on the negative inotropic action of dantrolene was tested in Langendorff-perfused hearts from euthyroid and hyperthyroid rats."3.68The effect of external calcium concentration on the negative inotropic action of dantrolene in isolated hyperthyroid and euthyroid heart. ( Butkow, N; Wheatley, AM, 1991)
"1 The effects of dantrolene on twitch and tetanic force development were determined in soleus and gastrocnemius muscle of euthyroid, hypothyroid, and hyperthyroid rats."3.67Effects of dantrolene on force development in slow- and fast-twitch muscle of euthyroid, hypothyroid, and hyperthyroid rats. ( Everts, ME; van Hardeveld, C, 1987)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
van Hardeveld, C2
Kassenaar, AA1
Wheatley, AM1
Butkow, N1
Everts, ME2
Clausen, T1

Other Studies

4 other studies available for dantrolene and Hyperthyroidism

ArticleYear
A possible role for Ca2+ in thyroid hormone-dependent oxygen consumption in skeletal muscle of the rat.
    FEBS letters, 1980, Dec-01, Volume: 121, Issue:2

    Topics: Animals; Calcium; Dantrolene; Hyperthyroidism; Hypothyroidism; In Vitro Techniques; Male; Muscles; O

1980
The effect of external calcium concentration on the negative inotropic action of dantrolene in isolated hyperthyroid and euthyroid heart.
    Pharmacological research, 1991, Volume: 24, Issue:1

    Topics: Animals; Calcium; Dantrolene; Depression, Chemical; Hyperthyroidism; In Vitro Techniques; Male; Myoc

1991
Effects of dantrolene on force development in slow- and fast-twitch muscle of euthyroid, hypothyroid, and hyperthyroid rats.
    British journal of pharmacology, 1987, Volume: 92, Issue:1

    Topics: Animals; Dantrolene; Electric Stimulation; Hyperthyroidism; Hypothyroidism; Male; Muscle Contraction

1987
Effects of thyroid hormones on calcium contents and 45Ca exchange in rat skeletal muscle.
    The American journal of physiology, 1986, Volume: 251, Issue:3 Pt 1

    Topics: Animals; Calcium; Calcium Radioisotopes; Dantrolene; Female; Gallopamil; Hyperthyroidism; Hypothyroi

1986