dantrolene has been researched along with Hemiplegia in 9 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
Hemiplegia: Severe or complete loss of motor function on one side of the body. This condition is usually caused by BRAIN DISEASES that are localized to the cerebral hemisphere opposite to the side of weakness. Less frequently, BRAIN STEM lesions; cervical SPINAL CORD DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; and other conditions may manifest as hemiplegia. The term hemiparesis (see PARESIS) refers to mild to moderate weakness involving one side of the body.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present the case of a 42-year-old male with a history of schizophrenia who developed signs and symptoms consistent with Neuroleptic Malignant Syndrome (NMS) after 3 weeks of treatment with Olanzapine." | 7.70 | Neuroleptic malignant syndrome associated with olanzapine therapy: a case report. ( Privette, T; Stanfield, SC, 2000) |
| "Dantrolene sodium is a valuable tool in the management of spasticity due to hemiplegia." | 5.25 | Effect of dantrolene sodium on spasticity associated with hemiplegia. ( Ferguson, KL; Steinberg, FU, 1975) |
| "We present the case of a 42-year-old male with a history of schizophrenia who developed signs and symptoms consistent with Neuroleptic Malignant Syndrome (NMS) after 3 weeks of treatment with Olanzapine." | 3.70 | Neuroleptic malignant syndrome associated with olanzapine therapy: a case report. ( Privette, T; Stanfield, SC, 2000) |
| "Dantrolene sodium was effective in controlling spasticity and improving function in 11 of 13 patients taking part in a 14-week double-blind crossover study." | 1.25 | Efficacy of dantrolene sodium in the treatment of spasticity. ( Chipman, M; Kaul, S; Lambie, M, 1974) |
| "Dantrolene sodium is a valuable tool in the management of spasticity due to hemiplegia." | 1.25 | Effect of dantrolene sodium on spasticity associated with hemiplegia. ( Ferguson, KL; Steinberg, FU, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (88.89) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chipman, M | 1 |
| Kaul, S | 1 |
| Lambie, M | 1 |
| Chantraine, A | 1 |
| van Ouwenaller, C | 1 |
| Stanfield, SC | 1 |
| Privette, T | 1 |
| Pinder, RM | 1 |
| Brogden, RN | 1 |
| Speight, TM | 1 |
| Avery, GS | 1 |
| Jonsson, B | 1 |
| Ladd, H | 1 |
| Afzelius-Frisk, I | 1 |
| Lindberg-Broman, AM | 1 |
| Steinberg, FU | 1 |
| Ferguson, KL | 1 |
| Freedman, W | 2 |
| Herman, R | 2 |
| Nakamura, R | 1 |
| Tsuji, I | 1 |
| Mayer, N | 1 |
1 review available for dantrolene and Hemiplegia
| Article | Year |
|---|---|
Dantrolene sodium: a review of its pharmacological properties and therapeutic efficacy in spasticity.
Topics: Adult; Animals; Cats; Cerebral Palsy; Chemical and Drug Induced Liver Injury; Child; Clinical Trials | 1977 |
1 trial available for dantrolene and Hemiplegia
| Article | Year |
|---|---|
Dantrolene sodium: a review of its pharmacological properties and therapeutic efficacy in spasticity.
Topics: Adult; Animals; Cats; Cerebral Palsy; Chemical and Drug Induced Liver Injury; Child; Clinical Trials | 1977 |
8 other studies available for dantrolene and Hemiplegia
| Article | Year |
|---|---|
Efficacy of dantrolene sodium in the treatment of spasticity.
Topics: Activities of Daily Living; Adult; Cross-Over Studies; Dantrolene; Dose-Response Relationship, Drug; | 1974 |
[Treatment of spasticity in neurological disease by dantrolen-sodium (author's transl)].
Topics: Adolescent; Adult; Aged; Dantrolene; Female; Hemiplegia; Humans; Male; Middle Aged; Multiple Scleros | 1980 |
Neuroleptic malignant syndrome associated with olanzapine therapy: a case report.
Topics: Adult; Anti-Bacterial Agents; Antipsychotic Agents; Benzodiazepines; Bromocriptine; Combined Modalit | 2000 |
The effect of dantrium on spasticity of hemiplegic patients.
Topics: Adolescent; Adult; Aged; Dantrolene; Drug Evaluation; Hemiplegia; Humans; Hydantoins; Middle Aged; M | 1975 |
Effect of dantrolene sodium on spasticity associated with hemiplegia.
Topics: Adult; Aged; Dantrolene; Fatigue; Follow-Up Studies; Gait; Hemiplegia; Humans; Hydantoins; Middle Ag | 1975 |
Inhibition of electromyographic activity in human triceps surae muscles during sinusoidal rotation of the foot.
Topics: Adult; Ankle; Dantrolene; Electromyography; Foot; Hemiplegia; Humans; Models, Biological; Motor Neur | 1975 |
Effect of antispastic drugs on rapid force generation of spastic muscle.
Topics: Adult; Aged; Baclofen; Dantrolene; Electromyography; Hemiplegia; Humans; Male; Middle Aged; Muscle C | 1986 |
Neurophysiologic mechanisms of hemiplegic and paraplegic spasticity: implications for therapy.
Topics: Ankle; Dantrolene; Diazepam; Electromyography; Hemiplegia; Humans; Knee; Motor Neurons; Muscle Relax | 1974 |