dantrolene has been researched along with Escherichia coli Infections in 1 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
Escherichia coli Infections: Infections with bacteria of the species ESCHERICHIA COLI.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We conclude that dantrolene decreases survival in bacterial sepsis and has no effect on survival in endotoxemia in rats." | 7.69 | Dantrolene, an inhibitor of intracellular calcium release, fails to increase survival in a rat model of intra-abdominal sepsis. ( Cameron, EM; Fink, MP; Menconi, MJ; Phipps, R; Zhuang, J, 1996) |
| "We conclude that dantrolene decreases survival in bacterial sepsis and has no effect on survival in endotoxemia in rats." | 3.69 | Dantrolene, an inhibitor of intracellular calcium release, fails to increase survival in a rat model of intra-abdominal sepsis. ( Cameron, EM; Fink, MP; Menconi, MJ; Phipps, R; Zhuang, J, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cameron, EM | 1 |
| Zhuang, J | 1 |
| Menconi, MJ | 1 |
| Phipps, R | 1 |
| Fink, MP | 1 |
1 other study available for dantrolene and Escherichia coli Infections
| Article | Year |
|---|---|
Dantrolene, an inhibitor of intracellular calcium release, fails to increase survival in a rat model of intra-abdominal sepsis.
Topics: Animals; Calcium; Dantrolene; Disease Models, Animal; Escherichia coli Infections; Lactates; Male; P | 1996 |