dantrolene has been researched along with Diabetes Mellitus, Type 2 in 2 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, a fatal malignant hyperthermia-like syndrome (MHLS) with rhabdomyolysis associated with new-onset diabetes mellitus and HHNS in adolescents has been described." | 1.33 | Approach to management of malignant hyperthermia-like syndrome in pediatric diabetes mellitus. ( Backeljauw, PF; Crimmins, NA; Kilbane, BJ; Mehta, S; Shanley, TP, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hollander, AS | 1 |
| Olney, RC | 1 |
| Blackett, PR | 1 |
| Marshall, BA | 1 |
| Kilbane, BJ | 1 |
| Mehta, S | 1 |
| Backeljauw, PF | 1 |
| Shanley, TP | 1 |
| Crimmins, NA | 1 |
1 review available for dantrolene and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Fatal malignant hyperthermia-like syndrome with rhabdomyolysis complicating the presentation of diabetes mellitus in adolescent males.
Topics: Adolescent; Dantrolene; Diabetes Mellitus, Type 2; Fatal Outcome; Humans; Hyperglycemic Hyperosmolar | 2003 |
1 other study available for dantrolene and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Approach to management of malignant hyperthermia-like syndrome in pediatric diabetes mellitus.
Topics: Adolescent; Black or African American; Butyryl-CoA Dehydrogenase; Child; Dantrolene; Diabetes Mellit | 2006 |