dantrolene has been researched along with Deficiency, Muscle Phosphorylase in 2 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Five patients with McArdle's disease entered a double-blind, placebo-controlled, cross-over study of dantrolene sodium." | 2.67 | Dantrolene sodium does influence the second-wind phenomenon in McArdle's disease. Electrophysiological evidence during exercise in a double-blind placebo-controlled, cross-over study in 5 patients. ( Braakhekke, JP; Joosten, EM; Poels, PJ; Stegeman, DF, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lane, RJ | 1 |
| Turnbull, DM | 1 |
| Hudgson, P | 1 |
| Walton, J | 1 |
| Poels, PJ | 1 |
| Braakhekke, JP | 1 |
| Joosten, EM | 1 |
| Stegeman, DF | 1 |
2 trials available for dantrolene and Deficiency, Muscle Phosphorylase
| Article | Year |
|---|---|
Trials of verapamil and dantrolene sodium in McArdle disease.
Topics: Calcium; Clinical Trials as Topic; Dantrolene; Glycogen Storage Disease; Glycogen Storage Disease Ty | 1984 |
Dantrolene sodium does influence the second-wind phenomenon in McArdle's disease. Electrophysiological evidence during exercise in a double-blind placebo-controlled, cross-over study in 5 patients.
Topics: Adult; Creatine Kinase; Dantrolene; Double-Blind Method; Electromyography; Exercise Test; Fatigue; F | 1990 |