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dantrolene and Coronary Disease

dantrolene has been researched along with Coronary Disease in 5 studies

Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.

Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.

Research Excerpts

ExcerptRelevanceReference
"The effects of dantrolene sodium on occlusion and reperfusion ventricular arrhythmias (VA) were studied in a canine model."7.67Effects of dantrolene sodium on occlusion and reperfusion arrhythmias in the canine heart. ( Belhassen, B; Chagnac, A; Laniado, S; Pelleg, A; Roth, A; Shargordsky, B, 1985)
"The effects of dantrolene sodium on occlusion and reperfusion ventricular arrhythmias (VA) were studied in a canine model."3.67Effects of dantrolene sodium on occlusion and reperfusion arrhythmias in the canine heart. ( Belhassen, B; Chagnac, A; Laniado, S; Pelleg, A; Roth, A; Shargordsky, B, 1985)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Freysz, M1
Timour, Q1
Bernaud, C1
Bertrix, L1
Faucon, G1
Adnet, P1
Krivosic-Horber, R1
Davidenko, J1
Delmar, M1
Oates, R1
Jalife, J1
Rubin, AS1
Zablocki, AD1
Pelleg, A1
Roth, A1
Shargordsky, B1
Belhassen, B1
Chagnac, A1
Laniado, S1

Reviews

1 review available for dantrolene and Coronary Disease

ArticleYear
[Calcium inhibitors and anesthesia].
    Annales francaises d'anesthesie et de reanimation, 1988, Volume: 7, Issue:6

    Topics: Analgesics; Anesthesia, General; Anesthetics; Arrhythmias, Cardiac; Brain Ischemia; Calcium Channel

1988

Other Studies

4 other studies available for dantrolene and Coronary Disease

ArticleYear
Cardiac implications of amlodipine-dantrolene combinations.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:1

    Topics: Amlodipine; Animals; Calcium Channel Blockers; Coronary Disease; Dantrolene; Drug Interactions; Drug

1996
Electrophysiological actions of dantrolene sodium in isolated sinoatrial and atrioventricular nodes and in a model of ischemia.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:1

    Topics: Action Potentials; Animals; Atrioventricular Node; Coronary Disease; Dantrolene; Electric Conductivi

1986
Hyperkalemia, verapamil, and dantrolene.
    Anesthesiology, 1987, Volume: 66, Issue:2

    Topics: Colectomy; Colonic Neoplasms; Coronary Disease; Dantrolene; Drug Interactions; Humans; Hyperkalemia;

1987
Effects of dantrolene sodium on occlusion and reperfusion arrhythmias in the canine heart.
    Methods and findings in experimental and clinical pharmacology, 1985, Volume: 7, Issue:5

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Coronary Disease; Dantrolene;

1985