dantrolene has been researched along with Contracture in 5 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
Contracture: Prolonged shortening of the muscle or other soft tissue around a joint, preventing movement of the joint.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The halothane/caffeine contracture test was performed on the biopsied muscle." | 3.69 | Incidence of malignant hyperthermia reactions in 2,214 patients undergoing muscle biopsy. ( Britt, BA; Carr, AS; Cunliffe, M; Lerman, J; McLeod, ME, 1995) |
| "Halothane-induced contractures in isolated muscle fibers from swine susceptible to malignant hyperthermia (MHS) were significantly less when fibers were incubated in KRB plus 6." | 3.65 | Porcine malignant hyperthermia: effect of dantrolene sodium on in-vitro halothane-induced contraction of susceptible muscle. ( Anderson, IL; Jones, EW, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bello, N | 1 |
| Adnet, P | 1 |
| Saulnier, F | 1 |
| Lestavel, P | 1 |
| Adnet-Bonte, C | 1 |
| Reyford, H | 1 |
| Etchrivi, T | 1 |
| Tavernier, B | 1 |
| Krivosic-Horber, R | 1 |
| Carr, AS | 1 |
| Lerman, J | 1 |
| Cunliffe, M | 1 |
| McLeod, ME | 1 |
| Britt, BA | 1 |
| Hainaut, K | 1 |
| Brunko, E | 1 |
| Desmedt, JE | 1 |
| Anderson, IL | 1 |
| Jones, EW | 1 |
| Azouvi, P | 1 |
| Roby-Brami, A | 1 |
| Tougeron, A | 1 |
| Bussel, B | 1 |
5 other studies available for dantrolene and Contracture
| Article | Year |
|---|---|
[Lack of sensitivity to per-anesthetic malignant hyperthermia in 32 patients who developed neuroleptic malignant syndrome].
Topics: Adolescent; Adult; Aged; Anesthesia, General; Caffeine; Contracture; Creatine Kinase; Dantrolene; Di | 1994 |
Incidence of malignant hyperthermia reactions in 2,214 patients undergoing muscle biopsy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, Conduction; Anes | 1995 |
Proceedings: Effect of dantrolene sodium on skeletal muscle contractions.
Topics: Aequorin; Animals; Anura; Biological Transport, Active; Calcium; Calcium Radioisotopes; Contracture; | 1975 |
Porcine malignant hyperthermia: effect of dantrolene sodium on in-vitro halothane-induced contraction of susceptible muscle.
Topics: Animals; Caffeine; Calcium; Contracture; Dantrolene; Halothane; Hydantoins; In Vitro Techniques; Mal | 1976 |
[Antispastic treatment of paraplegic patients].
Topics: Baclofen; Contracture; Dantrolene; Diazepam; Humans; Muscle Spasticity; Nursing Care; Paraplegia | 1988 |