dantrolene and Coma
dantrolene has been researched along with Coma in 3 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
Coma: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "On arrival, the Japan coma scale, pulse, respiratory rate, body temperature, and Sp(O2) were 300, 114 beats x min(-1), 26 breaths x min(-1), 39." | 1.38 | [Comatose patient with neuroleptic malignant syndrome brought by ambulance]. ( Kuroda, Y; Takinami, Y, 2012) |
| "We report a case of severe neuroleptic malignant syndrome developing in a 28-year-old female patient following deliberate self-poisoning with atypical antipsychotic drugs and serotonin reuptake inhibitors." | 1.36 | [Intensive care treatment for neuroleptic malignant syndrome]. ( Binder, C; Böhler, K; Hensel, M; Marnitz, R; von Brevern, M, 2010) |
Research
Studies (3)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Hensel, M | 1 |
| Böhler, K | 1 |
| Marnitz, R | 1 |
| Binder, C | 1 |
| von Brevern, M | 1 |
| Takinami, Y | 1 |
| Kuroda, Y | 1 |
| Knight, ME | 1 |
| Roberts, RJ | 1 |
Reviews
1 review available for dantrolene and Coma
| Article | Year |
|---|---|
Phenothiazine and butyrophenone intoxication in children.
Topics: Absorption; Adolescent; Basal Ganglia Diseases; Benztropine; Butyrophenones; Cardiovascular System; | 1986 |
Other Studies
2 other studies available for dantrolene and Coma
| Article | Year |
|---|---|
[Intensive care treatment for neuroleptic malignant syndrome].
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Coma; Creatin | 2010 |
[Comatose patient with neuroleptic malignant syndrome brought by ambulance].
Topics: Adult; Ambulances; Basal Ganglia Diseases; Chlorpromazine; Coma; Dantrolene; Drug Overdose; Female; | 2012 |