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dantrolene and Coagulation Disorders, Blood

dantrolene has been researched along with Coagulation Disorders, Blood in 4 studies

Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.

Research Excerpts

ExcerptRelevanceReference
"The cases of malignant hyperthermia reported on the most commonly used databases in China from 1985 to 2020 were analyzed."1.62Malignant hyperthermia when dantrolene is not readily available. ( Gong, X, 2021)
"Knock-in mice with the malignant hyperthermia susceptibility RYR1 mutation Y522S (MHS RYR1Y522S) had longer bleeding times than their wild-type littermates."1.43An RYR1 mutation associated with malignant hyperthermia is also associated with bleeding abnormalities. ( Alamelu, J; Brink, M; Byrne, S; Clement, E; Jungbluth, H; Lopez, RJ; Mohammed, S; Muntoni, F; Radunovic, A; Sekulic-Jablanovic, M; Snoeck, M; Treves, S; Voermans, N; Vukcevic, M; Wraige, E; Xu, L; Zhou, H; Zorzato, F, 2016)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Gong, X1
Lopez, RJ1
Byrne, S1
Vukcevic, M1
Sekulic-Jablanovic, M1
Xu, L1
Brink, M1
Alamelu, J1
Voermans, N1
Snoeck, M1
Clement, E1
Muntoni, F1
Zhou, H1
Radunovic, A1
Mohammed, S1
Wraige, E1
Zorzato, F1
Treves, S1
Jungbluth, H1
Watson, JD1
Ferguson, C1
Hinds, CJ1
Skinner, R1
Coakley, JH1
Dar, KJ1
McBrien, ME1

Reviews

2 reviews available for dantrolene and Coagulation Disorders, Blood

ArticleYear
Exertional heat stroke induced by amphetamine analogues. Does dantrolene have a place?
    Anaesthesia, 1993, Volume: 48, Issue:12

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Blood Coagulation Disorders; Dancing; Dantrolene;

1993
MDMA induced hyperthermia: report of a fatality and review of current therapy.
    Intensive care medicine, 1996, Volume: 22, Issue:9

    Topics: Acute Kidney Injury; Adolescent; Blood Coagulation Disorders; Dantrolene; Fatal Outcome; Fever; Hall

1996

Other Studies

2 other studies available for dantrolene and Coagulation Disorders, Blood

ArticleYear
Malignant hyperthermia when dantrolene is not readily available.
    BMC anesthesiology, 2021, 04-16, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Aged; Arterial Pressure; Blood Coagulation Disorders; Carbon Dioxide; Child; Chil

2021
An RYR1 mutation associated with malignant hyperthermia is also associated with bleeding abnormalities.
    Science signaling, 2016, 07-05, Volume: 9, Issue:435

    Topics: Amino Acid Substitution; Animals; Blood Coagulation Disorders; Calcium Signaling; Dantrolene; Female

2016