dantrolene has been researched along with Coagulation Disorders, Blood in 4 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The cases of malignant hyperthermia reported on the most commonly used databases in China from 1985 to 2020 were analyzed." | 1.62 | Malignant hyperthermia when dantrolene is not readily available. ( Gong, X, 2021) |
| "Knock-in mice with the malignant hyperthermia susceptibility RYR1 mutation Y522S (MHS RYR1Y522S) had longer bleeding times than their wild-type littermates." | 1.43 | An RYR1 mutation associated with malignant hyperthermia is also associated with bleeding abnormalities. ( Alamelu, J; Brink, M; Byrne, S; Clement, E; Jungbluth, H; Lopez, RJ; Mohammed, S; Muntoni, F; Radunovic, A; Sekulic-Jablanovic, M; Snoeck, M; Treves, S; Voermans, N; Vukcevic, M; Wraige, E; Xu, L; Zhou, H; Zorzato, F, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gong, X | 1 |
| Lopez, RJ | 1 |
| Byrne, S | 1 |
| Vukcevic, M | 1 |
| Sekulic-Jablanovic, M | 1 |
| Xu, L | 1 |
| Brink, M | 1 |
| Alamelu, J | 1 |
| Voermans, N | 1 |
| Snoeck, M | 1 |
| Clement, E | 1 |
| Muntoni, F | 1 |
| Zhou, H | 1 |
| Radunovic, A | 1 |
| Mohammed, S | 1 |
| Wraige, E | 1 |
| Zorzato, F | 1 |
| Treves, S | 1 |
| Jungbluth, H | 1 |
| Watson, JD | 1 |
| Ferguson, C | 1 |
| Hinds, CJ | 1 |
| Skinner, R | 1 |
| Coakley, JH | 1 |
| Dar, KJ | 1 |
| McBrien, ME | 1 |
2 reviews available for dantrolene and Coagulation Disorders, Blood
| Article | Year |
|---|---|
Exertional heat stroke induced by amphetamine analogues. Does dantrolene have a place?
Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Blood Coagulation Disorders; Dancing; Dantrolene; | 1993 |
MDMA induced hyperthermia: report of a fatality and review of current therapy.
Topics: Acute Kidney Injury; Adolescent; Blood Coagulation Disorders; Dantrolene; Fatal Outcome; Fever; Hall | 1996 |
2 other studies available for dantrolene and Coagulation Disorders, Blood
| Article | Year |
|---|---|
Malignant hyperthermia when dantrolene is not readily available.
Topics: Adolescent; Adult; Aged; Arterial Pressure; Blood Coagulation Disorders; Carbon Dioxide; Child; Chil | 2021 |
An RYR1 mutation associated with malignant hyperthermia is also associated with bleeding abnormalities.
Topics: Amino Acid Substitution; Animals; Blood Coagulation Disorders; Calcium Signaling; Dantrolene; Female | 2016 |